Genetics Department Seminar Series: "Copper Conducted Kinase Signal Transduction: Mechanisms and Vulnerabilities"

Our research program is founded in a new paradigm in nutrient sensing and protein regulation, termed metalloallostery, whereby redox-active metals control kinase activity. Our laboratory’s focus lies at the intersection of kinase signaling and copper (Cu) homeostasis with the goal of defining the mechanisms regulating Cu-dependent kinases in order to target them in cancer through drug development or repurposing.