Ya Ha PhD

Associate Professor of Pharmacology

Departments & Organizations

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Molecular Medicine, Pharmacology, and Physiology | Biochemistry, Biophysics and Structural Biology

Office of Student ResearchCancer Center, Yale: Developmental TherapeuticsPharmacology

Research Interests

Membrane protein; X-ray crystallography; Enzyme mechanism more...


  • B.S., Nanjing University, 1992
  • Ph.D., University of Minnesota, 1998

Selected Publications

  • Xue, Y., Chowdhury, S., Liu, X., Akiyama, Y., Ellman, J. & Ha, Y. (2012) Conformational change in rhomboid protease GlpG induced by inhibitor binding to its S’ subsites. Biochemistry 51, 3723-3731.
  • Xue, Y. & Ha, Y. (2012) The catalytic mechanism of rhomboid protease GlpG probed by 3,4-dichloroisocoumarin and diisopropyl fluorophosphonate. J. Biol. Chem. 287, 3099-3107.
  • Hu, J., Xue, Y., Lee, S. & Ha, Y. (2011) The crystal structure of GXGD membrane protease FlaK. Nature 475, 528-531.



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