Charles H Cha MD, FACS

Associate Professor of Surgery (Oncology and Gastrointestinal)

Departments & Organizations

Yale Medical Group

Office of Student ResearchCancer Center, Yale: Gastrointestinal Cancer Program; Developmental Therapeutics; Sarcoma Oncology ProgramSurgery: Oncology/General SurgeryDevelopmental Therapeutics

Research Interests

Development of robotic and laparoscopic approaches for benign and malignant conditions of the liver, pancreas and stomach; Effects of angiogenesis on gastrointestinal malignancy; Gene silencing techniques to knockdown proliferation of hepatocellular carcinoma in vitro and in vivo; Diagnostic and therapeutic utility of angiogenic inhibitors for treatment of solid tumors; Clinical outcomes in surgery for sarcoma, hepatobiliary, gastric and esophageal malignancy more...


  • B.S., Northwestern University, 1990
  • M.D., Northwestern University Medical School, 1995

Selected Publications

  • Cha C, Surgical therapy for hepatocellular carcinoma: formulating a rational approach. J Clin Gastroenterol. 2013 Jul;47:S30-6. PMID: 23751801
  • Nicholson, A., Guo, X., Sullivan, C., Cha, C. Automated Quantitative Analysis of Tissue Microarray of 443 Patients with Colorectal Adenocarcinoma: Low Expression of Bcl-2 Predicts Poor Survival. Journal of the American College of Surgeons, 2014. Epub ahead of print. PMID: 25127509
  • Fonseca AL, Cha CH. Hepatocellular carcinoma: A comprehensive overview of surgical therapy. J Surg Oncol. 2014. Epub ahead of print. PMID: 24894746



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