Biostatistics and Bioinformatics Core

The Biostatistics and Bioinformatics Core collaborates and supports the Yale SPORE in Lung Cancer projects on the statistical design and bioinformatics analysis of the individual projects and addresses the analytic questions arising from these projects. The Core plays an important role across the Yale Lung SPORE program because they have the responsibility to monitor the conduct of projects from a statistical perspective, including: the conduct of regular interim analyses, dynamic updates of power calculations, development of new biostatistical and bioinformatics methodology as needed. The Core will oversee data management services and ensure that data collected is of high quality and evaluated with statistical rigor. The Core is also responsible for bioinformatics including next generation sequencing data analysis, analyzing publically available genomic data, and the employment of appropriate methods to address the very high dimensional data generated from this SPORE.