2024
Patterns of sub‐optimal change following CBT for childhood anxiety
Bertie L, Arendt K, Coleman J, Cooper P, Creswell C, Eley T, Hartman C, Heiervang E, In‐Albon T, Krause K, Lester K, Marin C, Nauta M, Rapee R, Schneider S, Schniering C, Silverman W, Thastum M, Thirlwall K, Waite P, Wergeland G, Hudson J. Patterns of sub‐optimal change following CBT for childhood anxiety. Journal Of Child Psychology And Psychiatry 2024, 65: 1612-1623. PMID: 38817012, PMCID: PMC11563922, DOI: 10.1111/jcpp.14009.Peer-Reviewed Original ResearchCognitive behavioral therapyAnxiety disordersAnxiety diagnosesGrowth curve modelsMinimal respondersGroup cognitive behavioral therapyPatterns of symptom changeCurve modelClinically anxious youthSocial anxiety disorderAssociated with significantly less improvementResponse patternsAssess patterns of changeAnxious youthDisorder remissionChildhood anxietyMaternal psychopathologyBehavioral therapyDisorder severityDiagnostic statusSymptom changePre-and post-treatmentDelayed respondersAnxietyParental factors
2022
Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood?
Saavedra LM, Morgan-López AA, West SG, Alegría M, Silverman WK. Mitigating Multiple Sources of Bias in a Quasi-Experimental Integrative Data Analysis: Does Treating Childhood Anxiety Prevent Substance Use Disorders in Late Adolescence/Young Adulthood? Prevention Science 2022, 24: 1622-1635. PMID: 36057023, DOI: 10.1007/s11121-022-01422-z.Peer-Reviewed Original ResearchConceptsStudy-related treatmentYoung adulthoodPropensity scoreLong-term followDrug use disordersAdolescence/young adulthoodQuasi-experimental designLate adolescence/young adulthoodClinical trialsSubstance use disorder severityLong-term effectsChild anxiety disordersEpidemiological studiesIntegrative data analysisAnxiety disorder treatmentUse disordersDisorder treatmentAnxiety disordersControl participantsEpidemiological sampleClinical samplesDisorder severityTrialsLong-term assessmentDisorders
2016
Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders
Lester KJ, Coleman JR, Roberts S, Keers R, Breen G, Bögels S, Creswell C, Hudson JL, McKinnon A, Nauta M, Rapee RM, Schneider S, Silverman WK, Thastum M, Waite P, Wergeland GJ, Eley TC. Genetic variation in the endocannabinoid system and response to Cognitive Behavior Therapy for child anxiety disorders. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2016, 174: 144-155. PMID: 27346075, PMCID: PMC5324578, DOI: 10.1002/ajmg.b.32467.Peer-Reviewed Original ResearchConceptsAnxiety disorder diagnosisIndividual differencesPrimary anxiety disorder diagnosisSuccessful psychological treatmentDisorder diagnosisCognitive behavior therapyAnxiety disorder severityExtinction learningFear extinctionPsychological treatmentBehavior therapyDisorder severityPoor treatment responseSymptom severityEffect sizeFull sampleEndocannabinoid systemFearTreatment responseCBTAnxietyPotential clinical utilityLimited evidenceLearningChildren