2004
Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slices
Huang H, Barakat L, Wang D, Bordey A. Bergmann glial GlyT1 mediates glycine uptake and release in mouse cerebellar slices. The Journal Of Physiology 2004, 560: 721-736. PMID: 15331688, PMCID: PMC1665288, DOI: 10.1113/jphysiol.2004.067801.Peer-Reviewed Original ResearchConceptsWhole-cell patch-clamp recordingsGlycine receptor blockerMouse cerebellar slicesNMDA receptor activationVoltage-dependent inward currentsExtracellular glycine levelsPatch-clamp recordingsDependent glycine transportersReceptor blockersInhibitory neurotransmitterNMDA receptorsGlycine levelsBergmann gliaCerebellar slicesInward currentsReceptor activationGlycine transporterGliaGlycine transportGlyT1Glycine uptakeBlockersAgonistsIntact systemNeurones
2003
Modulation of Glutamatergic Transmission by Bergmann Glial Cells in Rat Cerebellum In Situ
Bordey A, Sontheimer H. Modulation of Glutamatergic Transmission by Bergmann Glial Cells in Rat Cerebellum In Situ. Journal Of Neurophysiology 2003, 89: 979-988. PMID: 12574474, DOI: 10.1152/jn.00904.2002.Peer-Reviewed Original ResearchMeSH Keywords6-Cyano-7-nitroquinoxaline-2,3-dioneAmino Acid Transport System X-AGAnimalsAspartic AcidCell CommunicationElectric StimulationExcitatory Amino Acid AgonistsExcitatory Amino Acid AntagonistsExcitatory Postsynaptic PotentialsGlutamic AcidMembrane PotentialsN-MethylaspartateNerve FibersNeurogliaPatch-Clamp TechniquesPurkinje CellsRatsRats, Sprague-DawleyReceptors, GlutamateSodiumSynaptic TransmissionConceptsExcitatory postsynaptic currentsBergmann glial cellsGlial cellsPurkinje cell synapseInward currentsCell synapseGlu transportPurkinje cellsSpontaneous excitatory postsynaptic currentsAbsence of TTXPresynaptic glutamate releaseCerebellar brain slicesSpontaneous EPSC frequencyPatch-clamp recordingsSingle glial cellsIonotropic Glu receptorsParallel fibersEPSC frequencyPresynaptic effectsExcitatory transmissionGlutamate releaseGlutamatergic transmissionPostsynaptic currentsGlu receptorsBrain slices
2002
GAT-1 and Reversible GABA Transport in Bergmann Glia in Slices
Barakat L, Bordey A. GAT-1 and Reversible GABA Transport in Bergmann Glia in Slices. Journal Of Neurophysiology 2002, 88: 1407-1419. PMID: 12205162, DOI: 10.1152/jn.2002.88.3.1407.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBiological TransportCarrier ProteinsCerebellumElectrophysiologyGABA Plasma Membrane Transport ProteinsGamma-Aminobutyric AcidIn Vitro TechniquesMembrane ProteinsMembrane Transport ProteinsNeurogliaOrganic Anion TransportersPatch-Clamp TechniquesRatsRats, Sprague-DawleyReceptors, GABA-AConceptsGAT-1Bergmann gliaInward currentsGABA transporterWhole-cell patch-clamp recordingsCell patch-clamp recordingsGlial GABA uptakePatch-clamp recordingsRat cerebellar slicesGABA perfusionReceptor blockersAmbient GABANNC-711Extracellular GABAGABA effluxGABA uptakeGABA receptorsCerebellar slicesGAT subtypesNipecotic acidReceptor activationGABABlockersGliaOutward currentsCarrier‐mediated uptake and release of taurine from Bergmann glia in rat cerebellar slices
Barakat L, Wang D, Bordey A. Carrier‐mediated uptake and release of taurine from Bergmann glia in rat cerebellar slices. The Journal Of Physiology 2002, 541: 753-767. PMID: 12068038, PMCID: PMC2290349, DOI: 10.1113/jphysiol.2001.015834.Peer-Reviewed Original ResearchConceptsRat cerebellar slicesBergmann gliaGuanidinoethyl sulphonateCerebellar slicesTaurine transporterInward currentsWhole-cell patch-clamp recordingsTaurine uptakeGABA receptor blockersTaurine transporter inhibitorRelease of taurinePatch-clamp recordingsDependent taurine transporterOrder of potencyTaurine perfusionReceptor blockersIntracellular taurineIschemic conditionsCarrier-mediated uptakeTaurine effluxOutward currentsTransporter currentsTransporter inhibitorsIntracellular perfusionGlia