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In the world of musculoskeletal oncology, a specialized orthopedic surgeon acts as both an architect and a demolition expert. When a patient is diagnosed with osteosarcoma, an aggressive form of bone cancer, the mission is to remove the tumor entirely. Leaving behind even a microscopic cluster of malignant cells can be the difference between remission and cancer recurrence.

Yale researchers were able to quickly initiate a clinical trial for treating adolescent brain tumors after discovering gene mutations that could be targeted with existing drugs.

The American Society for Clinical Investigation is one of the nation’s oldest medical honor societies.

In the first of a three-part Q&A series with autism expert James McPartland, PhD, he offers historical context on autism and discusses treatment approaches and prevalence trends. He also touches on what is known about causes, some of the limitations in autism diagnosis, and the promise of biomarker research, which foreshadows part two of this Q&A series. McPartland serves as director of the Developmental Disabilities Clinic and Harris Professor at Yale Child Study Center.

Dr. Eric Winer, the director of the Yale Cancer Center, explained that one way blood cancer tests, or so-called liquid biopsies, are used is to monitor cancer patients. “Somebody has had treatment for cancer, and we’re trying to predict their risk of having a recurrence of cancer,” Winer said.

Despite major advances in our understanding of the biology of mental health disorders,  there’s no blood test or brain scan that will confirm if you have depression, anxiety, PTSD, or any other psychiatric illness. John H. Krystal, MD, chair of the Yale Department of Psychiatry, helps to explain why in an interview with WNYC.

Gabriel P.A. Costa, MD, left, and Joao P. De Aquino, MD, right, are first and senior authors, respectively, of a systematic review and meta-analysis in Molecular Psychiatry of 63 preclinical and human studies evaluating endocannabinoid system modulators for alcohol use disorder.

John H. Krystal, MD, chair of the Yale Department of Psychiatry, recalls the "thrill" of presenting cartoonist and Doonesbury comic strip creator Garry Trudeau with the department's Mental Health Advocacy Award in 2008. "For far too long, PTSD among combat veterans was essentially invisible in America," Krystal recently told the Yale Alumni Magazine. "We in the Yale Department of Psychiatry were thrilled to honor Garry Trudeau for his healing cartoons and his advocacy for those afflicted with combat-related PTSD.”

In 1896, Yale physicist Arthur Wright produced one of America’s first X-ray images, helping launch modern medical imaging in the United States.