Ketu Mishra-Gorur, MSc, MS, PhD
Associate Professor TermCards
About
Research
Publications
2025
Subgroup of meningiomas involving FOS and FOSB gene fusions
Yalcin K, Alanya H, Gultekin B, Samper Figuera D, Barak T, Miyagishima D, Youngblood M, Hjerthen M, Brooks A, Samuel Lopez N, O’Brien J, Chavez M, Dincer A, Wu H, Omay S, Yasuno K, Bilguvar K, Ercan-Sencicek A, Mishra-Gorur K, McGuone D, Moliterno J, Gunel M, Erson-Omay E. Subgroup of meningiomas involving FOS and FOSB gene fusions. Nature Communications 2025, 16: 10532. PMID: 41298363, PMCID: PMC12657970, DOI: 10.1038/s41467-025-65549-7.Peer-Reviewed Original ResearchCase Report: Genomic characterization of a rare skull-base plasmacytoma
Alanya H, Kasturi S, Yalcin K, Gultekin B, Kumar D, Samuel N, Figuera D, Mishra-Gorur K, Gunel M, Erson-Omay E, Omay S. Case Report: Genomic characterization of a rare skull-base plasmacytoma. Frontiers In Oncology 2025, 15: 1645502. PMID: 41378284, PMCID: PMC12685666, DOI: 10.3389/fonc.2025.1645502.Peer-Reviewed Original ResearchDysregulation of Protein Kinase CaMKI Leads to Autism-Related Phenotypes in Synaptic Connectivity, Sleep, Sociality, and Aging-Dependent Degeneration in Drosophila
Gualtieri C, Smith Z, Cruz A, Khan Z, Jenkins C, Mishra-Gorur K, Vonhoff F. Dysregulation of Protein Kinase CaMKI Leads to Autism-Related Phenotypes in Synaptic Connectivity, Sleep, Sociality, and Aging-Dependent Degeneration in Drosophila. Biology 2025, 14: 1228. PMID: 41007373, PMCID: PMC12467204, DOI: 10.3390/biology14091228.Peer-Reviewed Original ResearchSomatic SMARCB1 mutation in spinal meningioma represents branched evolution in a patient with multiple sporadic meningiomas
Gupta M, Samiappan S, Alanya H, Yalcin K, Gultekin B, Sharaf R, Elsamadicy A, Figuera D, Samuel N, Mishra-Gorur K, Kolb L, McGuone D, Gunel M, Erson-Omay E, Moliterno J, Mendel E. Somatic SMARCB1 mutation in spinal meningioma represents branched evolution in a patient with multiple sporadic meningiomas. Neuro-Oncology Advances 2025, 7: vdaf067. PMID: 40386121, PMCID: PMC12081948, DOI: 10.1093/noajnl/vdaf067.Peer-Reviewed Original ResearchDysregulation of mTOR signalling is a converging mechanism in lissencephaly
Zhang C, Liang D, Ercan-Sencicek A, Bulut A, Cortes J, Cheng I, Henegariu O, Nishimura S, Wang X, Peksen A, Takeo Y, Caglar C, Lam T, Koroglu M, Narayanan A, Lopez-Giraldez F, Miyagishima D, Mishra-Gorur K, Barak T, Yasuno K, Erson-Omay E, Yalcinkaya C, Wang G, Mane S, Kaymakcalan H, Guzel A, Caglayan A, Tuysuz B, Sestan N, Gunel M, Louvi A, Bilguvar K. Dysregulation of mTOR signalling is a converging mechanism in lissencephaly. Nature 2025, 638: 172-181. PMID: 39743596, PMCID: PMC11798849, DOI: 10.1038/s41586-024-08341-9.Peer-Reviewed Original Research
2024
CC2D1A causes ciliopathy, intellectual disability, heterotaxy, renal dysplasia, and abnormal CSF flow
Kim A, Sakin I, Viviano S, Tuncel G, Aguilera S, Goles G, Jeffries L, Ji W, Lakhani S, Kose C, Silan F, Oner S, Kaplan O, Group M, Ergoren M, Mishra-Gorur K, Gunel M, Sag S, Temel S, Deniz E. CC2D1A causes ciliopathy, intellectual disability, heterotaxy, renal dysplasia, and abnormal CSF flow. Life Science Alliance 2024, 7: e202402708. PMID: 39168639, PMCID: PMC11339347, DOI: 10.26508/lsa.202402708.Peer-Reviewed Original ResearchVariations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group.
Tabor J, Dincer A, O'Brien J, Lei H, Vetsa S, Vasandani S, Jalal M, Yalcin K, Morales-Valero S, Marianayagam N, Alanya H, Elsamadicy A, Millares Chavez M, Aguilera S, Mishra-Gorur K, McGuone D, Fulbright R, Jin L, Erson-Omay E, Günel M, Moliterno J. Variations in the genomic profiles and clinical behavior of meningioma by racial and ethnic group. Journal Of Neurosurgery 2024, 141: 664-672. PMID: 38518289, DOI: 10.3171/2024.1.jns231633.Peer-Reviewed Original ResearchReply to Pisan et al.: Pathogenicity of inherited TRAF7 mutations in congenital heart disease
Mishra-Gorur K, Barak T, Kaulen L, Henegariu O, Jin S, Aguilera S, Yalbir E, Goles G, Nishimura S, Miyagishima D, Djenoune L, Altinok S, K. D, Viviano S, Prendergast A, Zerillo C, Ozcan K, Baran B, Sencar L, Goc N, Yarman Y, Ercan-encicek A, Bilguvar K, Lifton R, Moliterno J, Louvi A, Yuan S, Deniz E, Brueckner M, Gunel M. Reply to Pisan et al.: Pathogenicity of inherited TRAF7 mutations in congenital heart disease. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2319578121. PMID: 38466853, PMCID: PMC10963000, DOI: 10.1073/pnas.2319578121.Commentaries, Editorials and Letters
2023
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas
Youngblood M, Erson-Omay Z, Li C, Najem H, Coșkun S, Tyrtova E, Montejo J, Miyagishima D, Barak T, Nishimura S, Harmancı A, Clark V, Duran D, Huttner A, Avşar T, Bayri Y, Schramm J, Boetto J, Peyre M, Riche M, Goldbrunner R, Amankulor N, Louvi A, Bilgüvar K, Pamir M, Özduman K, Kilic T, Knight J, Simon M, Horbinski C, Kalamarides M, Timmer M, Heimberger A, Mishra-Gorur K, Moliterno J, Yasuno K, Günel M. Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas. Nature Communications 2023, 14: 6279. PMID: 37805627, PMCID: PMC10560290, DOI: 10.1038/s41467-023-41926-y.Peer-Reviewed Original ResearchClinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas.
Tabor J, O'Brien J, Vasandani S, Vetsa S, Lei H, Jalal M, Marianayagam N, Jin L, Millares Chavez M, Haynes J, Dincer A, Yalcin K, Aguilera S, Omay S, Mishra-Gorur K, McGuone D, Morales-Valero S, Fulbright R, Gunel M, Erson-Omay E, Moliterno J. Clinical and genomic differences in supratentorial versus infratentorial NF2 mutant meningiomas. Journal Of Neurosurgery 2023, 139: 1648-1656. PMID: 37243548, DOI: 10.3171/2023.4.jns222929.Peer-Reviewed Original Research
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Neurosurgery
Dept. of Neurosurgery, PO Box 208082
New Haven, CT 06520-8082
United States