Jonadab Dos Santos Silva, MD, PhD
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Hospital Resident
Biography
Jonadab dos Santos Silva is a physician and researcher with a background in neurology and neuroimaging. He graduated with a degree in medicine from the Fluminense Federal University in Brazil. He also attended UCLA during medical school. He was a postdoctoral research fellow at the Icahn School of Medicine, where he worked on the clinical and cognitive manifestations of multiple sclerosis using ultra-high-field MRI to study the mechanisms of cortical lesion formation and repair, as well as how these processes are related to brain remodeling and disease progression. He has worked with various modalities in clinical studies, such as structural and functional MRI, EEG source localization, and tractography. His primary interests are the interplay between brain lesions and their clinical and cognitive manifestations, and his work aims to translate cutting-edge research into clinical practice, enhancing diagnostic and therapeutic strategies for patients with neurological conditions.
Departments & Organizations
Education & Training
- PhD
- Universidade Federal Fluminense, Neurology (2025)
- Postdoctoral Research Fellow
- Icahn School of Medicine at Mount Sinai (2024)
- MD
- Universidade Federal Fluminense, Medicine (2022)
- MD
- University of California, Los Angeles, Medicine, Exchange Program (2016)
Research
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Overview
Medical Research Interests
ORCID
0000-0002-4216-333X
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Andrew Solomon, PhD
Magnetic Resonance Imaging
Multiple Sclerosis
Diffusion Tensor Imaging
Neuroimaging
Publications
2026
Cannabinoids for Alzheimer's disease: A promising trial, although not yet ready for the prescription pad.
Dos Santos Silva J. Cannabinoids for Alzheimer's disease: A promising trial, although not yet ready for the prescription pad. Journal Of Alzheimer’s Disease 2026, 13872877261452183. PMID: 42216668, DOI: 10.1177/13872877261452183.Peer-Reviewed Original ResearchAltmetricCollaborative Latin American Imaging Network In Neuroimmunology Research (BRAIMS): Rationale, Structure, Challenges, and Future Directions
Carnero Contentti E, Alonso R, Boldrini V, Cárcamo C, Casas M, Ciampi E, Damanesco A, Dos Santos Silva J, Rimkus C, Marrodan M, Navas C, Patrucco L, Pitombeira M, Ramari C, Sato H, Soler B, Treviño Frenk I, Wagner M, Ontaneda D, Becker J. Collaborative Latin American Imaging Network In Neuroimmunology Research (BRAIMS): Rationale, Structure, Challenges, and Future Directions. Multiple Sclerosis And Related Disorders 2026, 110: 107203. PMID: 42000450, DOI: 10.1016/j.msard.2026.107203.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAltmetricNeuroanatomical Correlates of Depressive Symptoms in Early Multiple Sclerosis
Dos Santos Silva J, La Rosa F, Dereskewicz E, Levy S, Graney R, Garcia N, Galasso J, Sumowski J, Beck E. Neuroanatomical Correlates of Depressive Symptoms in Early Multiple Sclerosis. Neurology Open Access 2026, 2 DOI: 10.1212/wn9.0000000000000050.Peer-Reviewed Original ResearchCitationsAltmetricEfficacy of vagus nerve stimulator during transition to adulthood in patients with treatment‐resistant epilepsy
dos Santos Silva J, Boas S, do Prado H, Bezerra D, Meira I. Efficacy of vagus nerve stimulator during transition to adulthood in patients with treatment‐resistant epilepsy. Epileptic Disorders 2026, 28: 142-154. PMID: 41553328, PMCID: PMC12964184, DOI: 10.1002/epd2.70133.Peer-Reviewed Original ResearchNeuroanatomical Correlates of Depressive Symptoms in Early Multiple Sclerosis
Dos Santos Silva, J., La Rosa, F., Dereskewicz, E., Levy, S., Graney, R., Garcia, N., Galasso, J., Sumowski, J. F., & Beck, E. S. (2026). Neuroanatomical correlates of depressive symptoms in early multiple sclerosis. Neurology Open Access, 2(1), e0050. https://doi.org/10.1212/WN9.0000000000000050Peer-Reviewed Original Research
2025
A Novel Convolutional Neural Network for Automated Multiple Sclerosis Brain Lesion Segmentation
Dereskewicz E, La Rosa F, Dos Santos Silva J, Sizer E, Kohli A, Wynen M, Mullins W, Maggi P, Levy S, Onyemeh K, Ayci B, Solomon A, Assländer J, Al‐Louzi O, Reich D, Sumowski J, Beck E. A Novel Convolutional Neural Network for Automated Multiple Sclerosis Brain Lesion Segmentation. Journal Of Neuroimaging 2025, 35: e70085. PMID: 40937688, PMCID: PMC12426979, DOI: 10.1111/jon.70085.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsCitationsAltmetricLesion‐Based Disconnectome Explains Cognitive Outcomes in Multiple Sclerosis
dos Santos Silva J, Vasconcelos C, Spedo C, Azevedo C, Lopes L, La Rosa F, Moura C, Nascimento O, Lopes F. Lesion‐Based Disconnectome Explains Cognitive Outcomes in Multiple Sclerosis. Journal Of Neuroimaging 2025, 35: e70081. PMID: 40898881, PMCID: PMC12405817, DOI: 10.1111/jon.70081.Peer-Reviewed Original ResearchCitationsAltmetricAcademia in the throes of faceless bureaucracy
Pansieri J, Menassa D, Figiel S, Pisa M, Lockhart A, Ricigliano V, Seferoglu M, Borrelli S, Pimentel V, Alpin N, Szejko N, Samadzadeh S, Boldrini V, Zarco L, Correa-Díaz E, Dos Santos Silva J, Gomez Figueroa E, Carnero Contentti E, Koc E, Dalla Costa G, Casallas-Vanegas A, Bakirtzis C, Gluscevic S, Carvajal R, Tunç A, Haider L. Academia in the throes of faceless bureaucracy. Brain 2025, 148: 3039-3042. PMID: 40488444, DOI: 10.1093/brain/awaf217.Commentaries, Editorials and LettersAltmetricExploring the Potential of 7T MRI for Brain Age Prediction
La Rosa F, Dereskewicz E, Silva J, Galasso J, Garcia N, Graney R, Levy S, Greenspan H, Reich D, Sumowski J, Cuadra M, Beck E. Exploring the Potential of 7T MRI for Brain Age Prediction. Proceedings Of The International Society For Magnetic Resonance In Medicine ... Scientific Meeting And Exhibition. 2025 DOI: 10.58530/2025/5100.Peer-Reviewed Original ResearchBrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis
La Rosa F, Dos Santos Silva J, Dereskewicz E, Invernizzi A, Cahan N, Galasso J, Garcia N, Graney R, Levy S, Verma G, Balchandani P, Reich D, Horton M, Greenspan H, Sumowski J, Cuadra M, Beck E. BrainAgeNeXt: Advancing brain age modeling for individuals with multiple sclerosis. Imaging Neuroscience 2025, 3: imag_a_00487. PMID: 40800843, PMCID: PMC12319810, DOI: 10.1162/imag_a_00487.Peer-Reviewed Original ResearchCitationsAltmetric
Academic Achievements & Community Involvement
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Activities
activity European Charcot Foundation
2022 - PresentProfessional OrganizationsFellowactivity Acta Neurologica Scandinavica
2025 - PresentJournal ServiceRevieweractivity Annals of Neuroscience
2025 - PresentJournal ServiceRevieweractivity Brain Imaging and Behavior
2025 - PresentJournal ServiceRevieweractivity Cerebrovascular Diseases
2025 - PresentJournal ServiceReviewer
Honors
honor Best poster, Neuroimaging at the BMEII Symposium
04/21/2023Other AwardBioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount SinaiDetailsUnited Stateshonor ACTRIMS Educational Grant Award
02/12/2023National AwardAmericas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS)DetailsUnited Stateshonor NAIMS Educational Grant Award
02/11/2023National AwardNorth American Imaging in MS CooperativeDetailsUnited Stateshonor CTRIMS-ECF Young Investigator Award & Best oral presentation
06/18/2022International AwardEuropean Charcot FoundationDetailsBrazilhonor Best abstract presentation, 20th Brazilian and International Congress of Neuropsychology
10/09/2021National AwardBrazilian Society of NeuropsychologyDetailsBrazil
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