Can Meng, MS, MPH
BiostatisticianAbout
Research
Publications
2025
Predicting Agitation Events in the Emergency Department Through Artificial Intelligence
Wong A, Sapre A, Wang K, Nath B, Shah D, Kumar A, Faustino I, Desai R, Hu Y, Robinson L, Meng C, Tong G, Bernstein S, Yonkers K, Melnick E, Dziura J, Taylor R. Predicting Agitation Events in the Emergency Department Through Artificial Intelligence. JAMA Network Open 2025, 8: e258927. PMID: 40332935, PMCID: PMC12059975, DOI: 10.1001/jamanetworkopen.2025.8927.Peer-Reviewed Original ResearchConceptsED visitsEmergency departmentAgitation eventsElectronic health record dataArea under the receiver operating characteristic curvePatient-centered careHealth service utilizationPrimary outcomeHealth record dataUrban health systemED visit dataMode of arrivalPrevention of agitationOutcome of agitationDiverse patient populationsRestraint ordersCross-sectional cohortService utilizationVital signsED sitesHealth systemMain OutcomesRestraint eventsRange of predicted probabilitiesVisit data
2024
A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials
Tong G, Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Macedo J, Meng C, Wang X, Caille A, Li F, Taljaard M. A review of current practice in the design and analysis of extremely small stepped-wedge cluster randomized trials. Clinical Trials 2024, 22: 45-56. PMID: 39377196, PMCID: PMC11810615, DOI: 10.1177/17407745241276137.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSmall-sample correctionsStepped-wedge cluster randomized trialCluster randomized trialSample size calculation methodGeneralized linear mixed modelsLongitudinal correlation structureSize calculation methodLinear mixed modelsPermutation testSample sizeBayesian approachRandomized trialsCorrelation structureMixed modelsBayesian analysisGeneralized Estimating EquationsPermutationMedian sample sizeIntervention conditionRandomization methodEquationsPredictors of Health-Related Quality of Life Among Women Participating in an Appointment-Based Cardiac Rehabilitation Program
Wright C, Fournier S, Deng Y, Meng C, Tucker K, Spatz E, Lichtman J, Zhu C, Dreyer R, Oen-Hsiao J. Predictors of Health-Related Quality of Life Among Women Participating in an Appointment-Based Cardiac Rehabilitation Program. The Journal Of Cardiovascular Nursing 2024, 40: 64-73. PMID: 38595128, DOI: 10.1097/jcn.0000000000001096.Peer-Reviewed Original ResearchHealth-related quality of lifeCR programSF-36 scoresSF-36Quality of lifeCardiac rehabilitationPredictors of health-related quality of lifeYale New Haven HealthShort-Form General Health SurveyCardiac rehabilitation programGeneral health surveyHealth-related qualityCardiovascular diseaseMultivariate linear regression modelChronic obstructive pulmonary diseaseMeasure HRQoL.CR adherenceCR entryPredictors of improvementRehabilitation programHealth outcomesHealth SurveyEvaluate sex differencesObstructive pulmonary diseaseSocioeconomic statusThe dementia care study (D‐CARE): Recruitment strategies and demographic characteristics of participants in a pragmatic randomized trial of dementia care
Yang M, Samper‐Ternent R, Volpi E, Green A, Lichtenstein M, Araujo K, Borek P, Charpentier P, Dziura J, Gill T, Galloway R, Greene E, Lenoir K, Peduzzi P, Meng C, Reese J, Shelton A, Skokos E, Summapund J, Unger E, Reuben D, Williamson J, Stevens A. The dementia care study (D‐CARE): Recruitment strategies and demographic characteristics of participants in a pragmatic randomized trial of dementia care. Alzheimer's & Dementia 2024, 20: 2575-2588. PMID: 38358084, PMCID: PMC11032530, DOI: 10.1002/alz.13698.Peer-Reviewed Original ResearchElectronic health recordsPragmatic clinical trialsRecruitment strategiesDementia careApproaches to dementia careDementia care studiesCommunity-dwelling dyadsDyads of personsDiagnosis of dementiaHealth system patientsDemographic characteristics of participantsPragmatic Randomized TrialCharacteristics of participantsPragmatic research studiesFamily caregiversHealth recordsHealth systemCare studiesPLWDSystem patientsDemographic characteristicsD-CAREDementiaCaregiversClinical trial sites
2023
Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022
Nevins P, Ryan M, Davis-Plourde K, Ouyang Y, Macedo J, Meng C, Tong G, Wang X, Ortiz-Reyes L, Caille A, Li F, Taljaard M. Adherence to key recommendations for design and analysis of stepped-wedge cluster randomized trials: A review of trials published 2016–2022. Clinical Trials 2023, 21: 199-210. PMID: 37990575, PMCID: PMC11003836, DOI: 10.1177/17407745231208397.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Simulating time-to-event data subject to competing risks and clustering: A review and synthesis
Meng C, Esserman D, Li F, Zhao Y, Blaha O, Lu W, Wang Y, Peduzzi P, Greene E. Simulating time-to-event data subject to competing risks and clustering: A review and synthesis. Statistical Methods In Medical Research 2022, 32: 305-333. PMID: 36412111, PMCID: PMC11654122, DOI: 10.1177/09622802221136067.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsLongitudinal Causal Inference of Cognitive Function and Depressive Symptoms in Elderly People
Yao P, Meng C. Longitudinal Causal Inference of Cognitive Function and Depressive Symptoms in Elderly People. Epidemiology Biostatistics And Public Health 2022, 12 DOI: 10.2427/11262.Peer-Reviewed Original ResearchDepressive symptomsMexican AmericansCognitive functionNoninstitutionalized Mexican AmericansIntervention of depressive symptomsHispanic Established PopulationsPrevention of cognitive impairmentYears of follow-upHealth outcomesHealth interventionsEstablished PopulationsCESDMedical conditionsSymptom historyElderly peopleEpidemiological studiesCognitive impairmentLongitudinal dataEldersHealthFollow-upSymptomsIndependent variablesMMSEAmericanImplementation of an Appointment‐Based Cardiac Rehabilitation Approach: A Single‐Center Experience
Wright CX, Fournier S, Deng Y, Meng C, Hiller S, Oen‐Hsiao J, Dreyer RP. Implementation of an Appointment‐Based Cardiac Rehabilitation Approach: A Single‐Center Experience. Journal Of The American Heart Association 2022, 11: e024066. PMID: 35499969, PMCID: PMC9238587, DOI: 10.1161/jaha.121.024066.Peer-Reviewed Original ResearchConceptsLogistic regression modelsHealth outcomesCR programSex/age subgroupMultivariable logistic regression modelCardiovascular disease populationsDose-response benefitsSingle-center experienceDietary fat intakeBenign prostatic hyperplasiaFinal logistic regression modelLack of exerciseYale New Haven HealthPredictors of completionRegression modelsBlack patientsFat intakeMean ageProstatic hyperplasiaBlack raceCR completionRisk factorsCardiovascular diseaseDisease populationAge subgroupsFrailty and outcomes following revascularization of lower-extremity peripheral artery disease: Insights from the Vascular Quality Initiative (VQI)
Al-Damluji MS, Smolderen KG, Meng C, Dai F, Nanna MG, Sumpio B, Henke P, Mena-Hurtado C. Frailty and outcomes following revascularization of lower-extremity peripheral artery disease: Insights from the Vascular Quality Initiative (VQI). Vascular Medicine 2022, 27: 251-257. PMID: 35485400, DOI: 10.1177/1358863x221083701.Peer-Reviewed Original ResearchConceptsRisk Analysis IndexVascular Quality InitiativeLower extremity revascularizationFrailty screening toolsMFI-5Lower extremity peripheral artery diseaseScreening toolFrailty detectionAddition of frailtyPAD risk factorsPeripheral artery diseasePAD populationRevascularization typeVascular cohortMajor amputationPerioperative outcomesArtery diseaseFrailty indexFrailty toolsAdjusted analysisUnplanned amputationRisk factorsHigher oddsPredictive valuePatientsDesign and analysis of partially randomized preference trials with propensity score stratification
Wang Y, Li F, Blaha O, Meng C, Esserman D. Design and analysis of partially randomized preference trials with propensity score stratification. Statistical Methods In Medical Research 2022, 31: 1515-1537. PMID: 35469503, PMCID: PMC10530658, DOI: 10.1177/09622802221095673.Peer-Reviewed Original Research
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