MRS Group Publications

2024

Transmembrane pH gradient imaging in rodent glioma models.Mishra SK, Santana JG, Mihailovic J, Hyder F, Coman D. NMR Biomed. 2024 May; 2024 Jan 23. PMID: 38263680.
VEGF-C prophylaxis favors lymphatic drainage and modulates neuroinflammation in a stroke model.Boisserand LSB, Geraldo LH, Bouchart J, El Kamouh MR, Lee S, Sanganahalli BG, Spajer M, Zhang S, Lee S, Parent M, Xue Y, Skarica M, Yin X, Guegan J, Boyé K, Saceanu Leser F, Jacob L, Poulet M, Li M, Liu X, Velazquez SE, Singhabahu R, Robinson ME, Askenase MH, Osherov A, Sestan N, Zhou J, Alitalo K, Song E, Eichmann A, Sansing LH, Benveniste H, Hyder F, Thomas JL. J Exp Med. 2024 Apr 1; 2024 Mar 5. PMID: 38442272.
Macro- and microvascular contributions to cerebral structural alterations in patients with asymptomatic carotid artery stenosis.Schmitzer L, Kaczmarz S, Göttler J, Hoffmann G, Kallmayer M, Eckstein HH, Hedderich DM, Kufer J, Zimmer C, Preibisch C, Hyder F, Sollmann N. J Cereb Blood Flow Metab. 2024 Mar 20; 2024 Mar 20. PMID: 38506325.
High-resolution extracellular pH imaging of liver cancer with multiparametric MR using Deep Image Prior.Dong S, Shewarega A, Chapiro J, Cai Z, Hyder F, Coman D, Duncan JS. NMR Biomed. 2024 Mar 15; 2024 Mar 15. PMID: 38488205.
Magnetic Resonance Spectroscopy Spectral Registration Using Deep Learning.Ma DJ, Yang Y, Harguindeguy N, Tian Y, Small SA, Liu F, Rothman DL, Guo J. J Magn Reson Imaging. 2024 Mar; 2023 Jul 4. PMID: 37401726.
Carbon Dots based Tissue Equivalent Dosimeter as an Ionizing Radiation Sensor.Dos Santos de Almeida W, Gomes Abegão LM, Vinicius Silva Alves A, de Oliveira Souza Silva J, Oliveira de Souza S, d'Errico F, Midori Sussuchi E. Chemistry. 2024 Feb 26; 2024 Jan 10. PMID: 38118132.
Transient Impairment in Microglial Function Causes Sex-Specific Deficits in Synaptic and Hippocampal Function in Mice Exposed to Early Adversity.Ahmed S, Polis B, Jamwal S, Sanganahalli BG, Kaswan ZM, Islam R, Kim D, Bowers C, Giuliano L, Biederer T, Hyder F, Kaffman A. bioRxiv. 2024 Feb 15; 2024 Feb 15. PMID: 38405887.
Effect of Incomplete Cryoablation and Matrix Metalloproteinase Inhibition on Intratumoral CD8(+) T-Cell Infiltration in Murine Hepatocellular Carcinoma.Shewarega A, Santana JG, Nam D, Berz A, Tefera J, Kahl V, Mishra SK, Coman D, Duncan J, Roberts SJ, Wetter A, Madoff DC, Chapiro J. Radiology. 2024 Feb. PMID: 38349244.
Cross-hemicord spinal fiber reorganization associates with cortical sensory and motor network expansion in the rat model of hemicontusion cervical spinal cord injury.Mihailovic JM, Sanganahalli BG, Hyder F, Chitturi J, Elkabes S, Heary RF, Kannurpatti SS. Neurosci Lett. 2024 Jan 18; 2023 Dec 21. PMID: 38141752.
Brain energy metabolism: A roadmap for future research.Rae CD, Baur JA, Borges K, Dienel G, Díaz-García CM, Douglass SR, Drew K, Duarte JMN, Duran J, Kann O, Kristian T, Lee-Liu D, Lindquist BE, McNay EC, Robinson MB, Rothman DL, Rowlands BD, Ryan TA, Scafidi J, Scafidi S, Shuttleworth CW, Swanson RA, Uruk G, Vardjan N, Zorec R, McKenna MC. J Neurochem. 2024 Jan 6; 2024 Jan 6. PMID: 38183680.
Multimodal measures of spontaneous brain activity reveal both common and divergent patterns of cortical functional organization.Vafaii H, Mandino F, Desrosiers-Grégoire G, O'Connor D, Markicevic M, Shen X, Ge X, Herman P, Hyder F, Papademetris X, Chakravarty M, Crair MC, Constable RT, Lake EMR, Pessoa L. Nat Commun. 2024 Jan 3; 2024 Jan 3. PMID: 38172111.

2023

Fluorescent liposomal nanocarriers for targeted drug delivery in ischemic stroke therapy.Arul MR, Alahmadi I, Turro DG, Ruikar A, Abdulmalik S, Williams JT, Sanganahalli BG, Liang BT, Verma R, Kumbar SG. Biomater Sci. 2023 Dec 5; 2023 Dec 5. PMID: 37902365.
Cortical GABA Levels Are Reduced in Post-Acute COVID-19 Syndrome.Marinkovic K, White DR, Alderson Myers A, Parker KS, Arienzo D, Mason GF. Brain Sci. 2023 Dec 1; 2023 Dec 1. PMID: 38137114.
Intrathecal delivery of nanoparticle PARP inhibitor to the cerebrospinal fluid for the treatment of metastatic medulloblastoma.Khang M, Lee JH, Lee T, Suh HW, Lee S, Cavaliere A, Rushing A, Geraldo LH, Belitzky E, Rossano S, de Feyter HM, Shin K, Huttner A, Roussel MF, Thomas JL, Carson RE, Marquez-Nostra B, Bindra RS, Saltzman WM. Sci Transl Med. 2023 Nov; 2023 Nov 1. PMID: 37910601.
Spatiotemporal features of neurovascular (un)coupling with stimulus-induced activity and hypercapnia challenge in cerebral cortex and olfactory bulb.James S, Sanggaard S, Akif A, Mishra SK, Sanganahalli BG, Blumenfeld H, Verhagen JV, Hyder F, Herman P. J Cereb Blood Flow Metab. 2023 Nov; 2023 Jun 21. PMID: 37340791.
Parallel detection of multi-contrast MRI and Deuterium Metabolic Imaging (DMI) for time-efficient characterization of neurological diseases.Liu Y, De Feyter HM, Corbin ZA, Fulbright RK, McIntyre S, Nixon TW, de Graaf RA. medRxiv. 2023 Oct 3; 2023 Oct 3. PMID: 37873422.
A multi-laboratory preclinical trial in rodents to assess treatment candidates for acute ischemic stroke.Lyden PD, Diniz MA, Bosetti F, Lamb J, Nagarkatti KA, Rogatko A, Kim S, Cabeen RP, Koenig JI, Akhter K, Arbab AS, Avery BD, Beatty HE, Bibic A, Cao S, Simoes Braga Boisserand L, Chamorro A, Chauhan A, Diaz-Perez S, Dhandapani K, Dhanesha N, Goh A, Herman AL, Hyder F, Imai T, Johnson CW, Khan MB, Kamat P, Karuppagounder SS, Kumskova M, Mihailovic JM, Mandeville JB, Morais A, Patel RB, Sanganahalli BG, Smith C, Shi Y, Sutariya B, Thedens D, Qin T, Velazquez SE, Aronowski J, Ayata C, Chauhan AK, Leira EC, Hess DC, Koehler RC, McCullough LD, Sansing LH. Sci Transl Med. 2023 Sep 20; 2023 Sep 20. PMID: 37729432.
Improvement of neutron sensitivity for lithium formate EPR dosemeters: a Monte Carlo analysis.D'Oca MC, Collura G, Gagliardo C, Bartolotta A, Romeo M, d'Errico F, Marrale M. Radiat Prot Dosimetry. 2023 Sep 18. PMID: 37721086.
Design and realization of a multi-coil array for B(0) field control in a compact 1.5T head-only MRI scanner.Theilenberg S, Shang Y, Ghazouani J, Kumaragamage C, Nixon TW, McIntyre S, Vaughan JT, Parkinson B, Garwood M, de Graaf RA, Juchem C. Magn Reson Med. 2023 Sep; 2023 May 5. PMID: 37145035.
[WITHDRAWN] Activation of transsulfuration pathway to maintain cysteine is a thermogenic checkpoint for the conservation of energy.Lee AH, Sugiura Y, Youm YH, Dlugos T, Maeda R, Coman D, Spadaro O, Sidorov S, Shchukina I, Andhey S, Smith SR, Ravussin E, Hyder F, Artyomov MN, Dixit VD. Res Sq. 2023 Jun 30; 2023 Jun 30. PMID: 37461682.
The impact of metabolism on the adaptation of organisms to environmental change.Rothman DL, Moore PB, Shulman RG. Front Cell Dev Biol. 2023; 2023 Jun 12. PMID: 37377740.
Author Correction: A consensus protocol for functional connectivity analysis in the rat brain.Grandjean J, Desrosiers-Gregoire G, Anckaerts C, Angeles-Valdez D, Ayad F, Barrière DA, Blockx I, Bortel A, Broadwater M, Cardoso BM, Célestine M, Chavez-Negrete JE, Choi S, Christiaen E, Clavijo P, Colon-Perez L, Cramer S, Daniele T, Dempsey E, Diao Y, Doelemeyer A, Dopfel D, Dvořáková L, Falfán-Melgoza C, Fernandes FF, Fowler CF, Fuentes-Ibañez A, Garin CM, Gelderman E, Golden CEM, Guo CCG, Henckens MJAG, Hennessy LA, Herman P, Hofwijks N, Horien C, Ionescu TM, Jones J, Kaesser J, Kim E, Lambers H, Lazari A, Lee SH, Lillywhite A, Liu Y, Liu YY, López-Castro A, López-Gil X, Ma Z, MacNicol E, Madularu D, Mandino F, Marciano S, McAuslan MJ, McCunn P, McIntosh A, Meng X, Meyer-Baese L, Missault S, Moro F, Naessens DMP, Nava-Gomez LJ, Nonaka H, Ortiz JJ, Paasonen J, Peeters LM, Pereira M, Perez PD, Pompilus M, Prior M, Rakhmatullin R, Reimann HM, Reinwald J, Del Rio RT, Rivera-Olvera A, Ruiz-Pérez D, Russo G, Rutten TJ, Ryoke R, Sack M, Salvan P, Sanganahalli BG, Schroeter A, Seewoo BJ, Selingue E, Seuwen A, Shi B, Sirmpilatze N, Smith JAB, Smith C, Sobczak F, Stenroos PJ, Straathof M, Strobelt S, Sumiyoshi A, Takahashi K, Torres-García ME, Tudela R, van den Berg M, van der Marel K, van Hout ATB, Vertullo R, Vidal B, Vrooman RM, Wang VX, Wank I, Watson DJG, Yin T, Zhang Y, Zurbruegg S, Achard S, Alcauter S, Auer DP, Barbier EL, Baudewig J, Beckmann CF, Beckmann N, Becq GJPC, Blezer ELA, Bolbos R, Boretius S, Bouvard S, Budinger E, Buxbaum JD, Cash D, Chapman V, Chuang KH, Ciobanu L, Coolen BF, Dalley JW, Dhenain M, Dijkhuizen RM, Esteban O, Faber C, Febo M, Feindel KW, Forloni G, Fouquet J, Garza-Villarreal EA, Gass N, Glennon JC, Gozzi A, Gröhn O, Harkin A, Heerschap A, Helluy X, Herfert K, Heuser A, Homberg JR, Houwing DJ, Hyder F, Ielacqua GD, Jelescu IO, Johansen-Berg H, Kaneko G, Kawashima R, Keilholz SD, Keliris GA, Kelly C, Kerskens C, Khokhar JY, Kind PC, Langlois JB, Lerch JP, López-Hidalgo MA, Manahan-Vaughan D, Marchand F, Mars RB, Marsella G, Micotti E, Muñoz-Moreno E, Near J, Niendorf T, Otte WM, Pais-Roldán P, Pan WJ, Prado-Alcalá RA, Quirarte GL, Rodger J, Rosenow T, Sampaio-Baptista C, Sartorius A, Sawiak SJ, Scheenen TWJ, Shemesh N, Shih YI, Shmuel A, Soria G, Stoop R, Thompson GJ, Till SM, Todd N, Van Der Linden A, van der Toorn A, van Tilborg GAF, Vanhove C, Veltien A, Verhoye M, Wachsmuth L, Weber-Fahr W, Wenk P, Yu X, Zerbi V, Zhang N, Zhang BB, Zimmer L, Devenyi GA, Chakravarty MM, Hess A. Nat Neurosci. 2023 Jun. PMID: 37072562.
Preclinical evaluation of a brain penetrant PARP PET imaging probe in rat glioblastoma and nonhuman primates.Chen B, Ojha DP, Toyonaga T, Tong J, Pracitto R, Thomas MA, Liu M, Kapinos M, Zhang L, Zheng MQ, Holden D, Fowles K, Ropchan J, Nabulsi N, De Feyter H, Carson RE, Huang Y, Cai Z. Eur J Nucl Med Mol Imaging. 2023 Jun; 2023 Feb 28. PMID: 36849748.
Hippocampal neurochemicals are associated with exercise group and intensity, psychological health, and general cognition in older adults.Reitlo LS, Mihailovic JM, Stensvold D, Wisløff U, Hyder F, Håberg AK. Geroscience. 2023 Jun; 2023 Jan 10. PMID: 36626020.
Neurovascular coupling is optimized to compensate for the increase in proton production from nonoxidative glycolysis and glycogenolysis during brain activation and maintain homeostasis of pH, pCO(2) (,) and pO(2).DiNuzzo M, Dienel GA, Behar KL, Petroff OA, Benveniste H, Hyder F, Giove F, Michaeli S, Mangia S, Herculano-Houzel S, Rothman DL. J Neurochem. 2023 May 7; 2023 May 7. PMID: 37150946.
In vivo imaging of cerebral glucose metabolism informs on subacute to chronic post-stroke tissue status - A pilot study combining PET and deuterium metabolic imaging.Meerwaldt AE, Straathof M, Oosterveld W, van Heijningen CL, van Leent MM, Toner YC, Munitz J, Teunissen AJ, Daemen CC, van der Toorn A, van Vliet G, van Tilborg GA, De Feyter HM, de Graaf RA, Hol EM, Mulder WJ, Dijkhuizen RM. J Cereb Blood Flow Metab. 2023 May; 2023 Jan 6. PMID: 36606595.
Mapping of exogenous choline uptake and metabolism in rat glioblastoma using deuterium metabolic imaging (DMI).Ip KL, Thomas MA, Behar KL, de Graaf RA, De Feyter HM. Front Cell Neurosci. 2023; 2023 Apr 28. PMID: 37187610.
Multimodal measures of spontaneous brain activity reveal both common and divergent patterns of cortical functional organization.Vafaii H, Mandino F, Desrosiers-Grégoire G, O'Connor D, Shen X, Ge X, Herman P, Hyder F, Papademetris X, Chakravarty M, Crair MC, Constable RT, Lake EM, Pessoa L. Res Sq. 2023 Apr 26; 2023 Apr 26. PMID: 37162818.
Measurement of neuro-energetics and neurotransmission in the rat olfactory bulb using (1) H and (1) H-[(13) C] NMR spectroscopy.Chowdhury GMI, Behar KL, Mason GF, Rothman DL, de Graaf RA. NMR Biomed. 2023 Apr 23; 2023 Apr 23. PMID: 37088548.
A consensus protocol for functional connectivity analysis in the rat brain.Grandjean J, Desrosiers-Gregoire G, Anckaerts C, Angeles-Valdez D, Ayad F, Barrière DA, Blockx I, Bortel A, Broadwater M, Cardoso BM, Célestine M, Chavez-Negrete JE, Choi S, Christiaen E, Clavijo P, Colon-Perez L, Cramer S, Daniele T, Dempsey E, Diao Y, Doelemeyer A, Dopfel D, Dvořáková L, Falfán-Melgoza C, Fernandes FF, Fowler CF, Fuentes-Ibañez A, Garin CM, Gelderman E, Golden CEM, Guo CCG, Henckens MJAG, Hennessy LA, Herman P, Hofwijks N, Horien C, Ionescu TM, Jones J, Kaesser J, Kim E, Lambers H, Lazari A, Lee SH, Lillywhite A, Liu Y, Liu YY, López-Castro A, López-Gil X, Ma Z, MacNicol E, Madularu D, Mandino F, Marciano S, McAuslan MJ, McCunn P, McIntosh A, Meng X, Meyer-Baese L, Missault S, Moro F, Naessens DMP, Nava-Gomez LJ, Nonaka H, Ortiz JJ, Paasonen J, Peeters LM, Pereira M, Perez PD, Pompilus M, Prior M, Rakhmatullin R, Reimann HM, Reinwald J, Del Rio RT, Rivera-Olvera A, Ruiz-Pérez D, Russo G, Rutten TJ, Ryoke R, Sack M, Salvan P, Sanganahalli BG, Schroeter A, Seewoo BJ, Selingue E, Seuwen A, Shi B, Sirmpilatze N, Smith JAB, Smith C, Sobczak F, Stenroos PJ, Straathof M, Strobelt S, Sumiyoshi A, Takahashi K, Torres-García ME, Tudela R, van den Berg M, van der Marel K, van Hout ATB, Vertullo R, Vidal B, Vrooman RM, Wang VX, Wank I, Watson DJG, Yin T, Zhang Y, Zurbruegg S, Achard S, Alcauter S, Auer DP, Barbier EL, Baudewig J, Beckmann CF, Beckmann N, Becq GJPC, Blezer ELA, Bolbos R, Boretius S, Bouvard S, Budinger E, Buxbaum JD, Cash D, Chapman V, Chuang KH, Ciobanu L, Coolen BF, Dalley JW, Dhenain M, Dijkhuizen RM, Esteban O, Faber C, Febo M, Feindel KW, Forloni G, Fouquet J, Garza-Villarreal EA, Gass N, Glennon JC, Gozzi A, Gröhn O, Harkin A, Heerschap A, Helluy X, Herfert K, Heuser A, Homberg JR, Houwing DJ, Hyder F, Ielacqua GD, Jelescu IO, Johansen-Berg H, Kaneko G, Kawashima R, Keilholz SD, Keliris GA, Kelly C, Kerskens C, Khokhar JY, Kind PC, Langlois JB, Lerch JP, López-Hidalgo MA, Manahan-Vaughan D, Marchand F, Mars RB, Marsella G, Micotti E, Muñoz-Moreno E, Near J, Niendorf T, Otte WM, Pais-Roldán P, Pan WJ, Prado-Alcalá RA, Quirarte GL, Rodger J, Rosenow T, Sampaio-Baptista C, Sartorius A, Sawiak SJ, Scheenen TWJ, Shemesh N, Shih YI, Shmuel A, Soria G, Stoop R, Thompson GJ, Till SM, Todd N, Van Der Linden A, van der Toorn A, van Tilborg GAF, Vanhove C, Veltien A, Verhoye M, Wachsmuth L, Weber-Fahr W, Wenk P, Yu X, Zerbi V, Zhang N, Zhang BB, Zimmer L, Devenyi GA, Chakravarty MM, Hess A. Nat Neurosci. 2023 Apr; 2023 Mar 27. PMID: 36973511.
Cytogenetic effects of β-particles in Allium cepa cells used as a biological indicator for radiation damages.Xavier MN, Torres Novaes JA, Cavalcante Silva AC, Silva Alves AV, Bryanne Araujo Santos MJ, de Moraes Pantaleão S, Scher R, d'Errico F, Oliveira de Souza S. J Environ Radioact. 2023 Apr; 2023 Jan 16. PMID: 36652762.
The early days of ex vivo (1) H, (13) C, and (31) P nuclear magnetic resonance in the laboratory of Dr. Robert G. Shulman from 1975 to 1995.Rothman DL, Behar KL, Petroff OAC, Shulman RG. NMR Biomed. 2023 Apr; 2023 Feb 6. PMID: 36424353.
A 3D atlas of functional human brain energetic connectome based on neuropil distribution.Yu Y, Akif A, Herman P, Cao M, Rothman DL, Carson RE, Agarwal D, Evans AC, Hyder F. Cereb Cortex. 2023 Mar 21. PMID: 36104858.
A tribute to Leif Hertz: The historical context of his pioneering studies of the roles of astrocytes in brain energy metabolism, neurotransmission, cognitive functions, and pharmacology identifies important, unresolved topics for future studies.Dienel GA, Schousboe A, McKenna MC, Rothman DL. J Neurochem. 2023 Mar 16; 2023 Mar 16. PMID: 36928655.
Why Hippocampal Glutamate Levels Are Elevated in Schizophrenia.Guo J, Rothman DL, Small SA. JAMA Psychiatry. 2023 Mar 1. PMID: 36696108.
MR Imaging-Based In Vivo Macrophage Imaging to Monitor Immune Response after Radiofrequency Ablation of the Liver.Santana JG, Petukhova-Greenstein A, Gross M, Hyder F, Pekurovsky V, Gottwald LA, Boustani A, Walsh JJ, Kucukkaya AS, Malpani R, Madoff DC, Goldberg SN, Ahmed M, Joshi N, Coman D, Chapiro J. J Vasc Interv Radiol. 2023 Mar; 2022 Nov 21. PMID: 36423815.
In vivo calibration of genetically encoded metabolite biosensors must account for metabolite metabolism during calibration and cellular volume.Dienel GA, Rothman DL. J Neurochem. 2023 Feb 1; 2023 Feb 1. PMID: 36726217.
Concerted roles of LRRTM1 and SynCAM 1 in organizing prefrontal cortex synapses and cognitive functions.de Arce KP, Ribic A, Chowdhury D, Watters K, Thompson GJ, Sanganahalli BG, Lippard ETC, Rohlmann A, Strittmatter SM, Missler M, Hyder F, Biederer T. Nat Commun. 2023 Jan 28; 2023 Jan 28. PMID: 36709330.
Decreased but diverse activity of cortical and thalamic neurons in consciousness-impairing rodent absence seizures.McCafferty C, Gruenbaum BF, Tung R, Li JJ, Zheng X, Salvino P, Vincent P, Kratochvil Z, Ryu JH, Khalaf A, Swift K, Akbari R, Islam W, Antwi P, Johnson EA, Vitkovskiy P, Sampognaro J, Freedman IG, Kundishora A, Depaulis A, David F, Crunelli V, Sanganahalli BG, Herman P, Hyder F, Blumenfeld H. Nat Commun. 2023 Jan 10; 2023 Jan 10. PMID: 36627270.
Q-Flux: A method to assess hepatic mitochondrial succinate dehydrogenase, methylmalonyl-CoA mutase, and glutaminase fluxes in vivo.Hubbard BT, LaMoia TE, Goedeke L, Gaspar RC, Galsgaard KD, Kahn M, Mason GF, Shulman GI. Cell Metab. 2023 Jan 3; 2022 Dec 13. PMID: 36516861.
In vivo cortical glutathione response to oral fumarate therapy in relapsing-remitting multiple sclerosis: A single-arm open-label phase IV trial using 7-Tesla (1)H MRS.Juchem C, Swanberg KM, Prinsen H, Pelletier D. Neuroimage Clin. 2023; 2023 Aug 15. PMID: 37651844.
Biological embedding of early trauma: the role of higher prefrontal synaptic strength.Tamman AJF, Jiang L, Averill CL, Mason GF, Averill LA, Abdallah CG. Eur J Psychotraumatol. 2023. PMID: 37642398.
Overexpression of UCP3 decreases mitochondrial efficiency in mouse skeletal muscle in vivo.Codella R, Alves TC, Befroy DE, Choi CS, Luzi L, Rothman DL, Kibbey RG, Shulman GI. FEBS Lett. 2023 Jan; 2022 Sep 27. PMID: 36114012.
Deuterium metabolic imaging of the human brain in vivo at 7 T.Serés Roig E, De Feyter HM, Nixon TW, Ruhm L, Nikulin AV, Scheffler K, Avdievich NI, Henning A, de Graaf RA. Magn Reson Med. 2023 Jan; 2022 Sep 5. PMID: 36063499.

2022

Fluorescently-tagged magnetic protein nanoparticles for high-resolution optical and ultra-high field magnetic resonance dual-modal cerebral angiography.Mishra SK, Herman P, Crair M, Constable RT, Walsh JJ, Akif A, Verhagen JV, Hyder F. Nanoscale. 2022 Dec 8; 2022 Dec 8. PMID: 36437785.
White matter abnormalities in the Hdc knockout mouse, a model of tic and OCD pathophysiology.Jindachomthong K, Yang C, Huang Y, Coman D, Rapanelli M, Hyder F, Dougherty J, Frick L, Pittenger C. Front Mol Neurosci. 2022; 2022 Nov 24. PMID: 36504678.
Proton Magnetic Resonance Spectroscopy in Post-Traumatic Stress Disorder-Updated Systematic Review and Meta-Analysis.Swanberg KM, Campos L, Abdallah CG, Juchem C. Chronic Stress (Thousand Oaks). 2022 Jan-Dec; 2022 Oct 9. PMID: 36237981.
Lateralized Supraspinal Functional Connectivity Correlate with Pain and Motor Dysfunction in Rat Hemicontusion Cervical Spinal Cord Injury.Sanganahalli BG, Pavuluri S, Chitturi J, Herman P, Elkabes S, Heary R, Hyder F, Kannurpatti SS. Neurotrauma Rep. 2022; 2022 Oct 3. PMID: 36337081.
Brain-targeting, acid-responsive antioxidant nanoparticles for stroke treatment and drug delivery.Zhang S, Peng B, Chen Z, Yu J, Deng G, Bao Y, Ma C, Du F, Sheu WC, Kimberly WT, Simard JM, Coman D, Chen Q, Hyder F, Zhou J, Sheth KN. Bioact Mater. 2022 Oct; 2022 Mar 7. PMID: 35386312.
EFFECT OF DIFFERENT SOLVENTS ON THE OPTICALLY STIMULATED LUMINESCENCE SIGNAL FROM MGB4O7:CE,LI-LOADED POLYMER FILMS.Santos CC, Valença JVB, d'Errico F, Machado R, Caldas LVE, Souza SO. Radiat Prot Dosimetry. 2022 Sep 22. PMID: 35863068.
Mechanistic stoichiometric relationship between the rates of neurotransmission and neuronal glucose oxidation: Reevaluation of and alternatives to the pseudo-malate-aspartate shuttle model.Rothman DL, Behar KL, Dienel GA. J Neurochem. 2022 Sep 11; 2022 Sep 11. PMID: 36089566.
Multiple sclerosis diagnosis and phenotype identification by multivariate classification of in vivo frontal cortex metabolite profiles.Swanberg KM, Kurada AV, Prinsen H, Juchem C. Sci Rep. 2022 Aug 16; 2022 Aug 16. PMID: 35974117.
Short symmetric and highly selective asymmetric first and second order gradient modulated offset independent adiabaticity (GOIA) pulses for applications in clinical MRS and MRSI.Kumaragamage C, Coppoli A, Brown PB, McIntyre S, Nixon TW, De Feyter HM, Mason GF, de Graaf RA. J Magn Reson. 2022 Aug; 2022 Jun 3. PMID: 35691241.
Rates of pyruvate carboxylase, glutamate and GABA neurotransmitter cycling, and glucose oxidation in multiple brain regions of the awake rat using a combination of [2-(13)C]/[1-(13)C]glucose infusion and (1)H-[(13)C]NMR ex vivo.McNair LM, Mason GF, Chowdhury GM, Jiang L, Ma X, Rothman DL, Waagepetersen HS, Behar KL. J Cereb Blood Flow Metab. 2022 Aug; 2022 Jan 20. PMID: 35048735.
Mapping oxidative metabolism in the human brain with calibrated fMRI in health and disease.Chen JJ, Uthayakumar B, Hyder F. J Cereb Blood Flow Metab. 2022 Jul; 2022 Mar 16. PMID: 35296177.
Interleaved fluid-attenuated inversion recovery (FLAIR) MRI and deuterium metabolic imaging (DMI) on human brain in vivo.Liu Y, De Feyter HM, Fulbright RK, McIntyre S, Nixon TW, de Graaf RA. Magn Reson Med. 2022 Jul; 2022 Feb 28. PMID: 35225375.
Human brain functional MRS reveals interplay of metabolites implicated in neurotransmission and neuroenergetics.Koush Y, Rothman DL, Behar KL, de Graaf RA, Hyder F. J Cereb Blood Flow Metab. 2022 Jun; 2022 Jan 26. PMID: 35078383.
Methylated tetra-amide derivatives of paramagnetic complexes for magnetic resonance biosensing with both BIRDS and CEST.Zakaria ABM, Huang Y, Coman D, Mishra SK, Mihailovic JM, Maritim S, Rojas-Quijano FA, Jurek P, Kiefer GE, Hyder F. NMR Biomed. 2022 Jun; 2022 Jan 27. PMID: 34970801.
A Novel Biomarker of Neuronal Glutamate Metabolism in Nonhuman Primates Using Localized (1)H-Magnetic Resonance Spectroscopy: Development and Effects of BNC375, an α7 Nicotinic Acetylcholine Receptor Positive Allosteric Modulator.Miller CO, Gantert LT, Previs SF, Chen Y, Anderson KD, Thomas JM, Sanacora G, Uslaner JM, Rothman DL, Mason GF. Biol Psychiatry Cogn Neurosci Neuroimaging. 2022 Jun; 2020 Sep 29. PMID: 33309567.
Thalamic activations in rat brain by fMRI during tactile (forepaw, whisker) and non-tactile (visual, olfactory) sensory stimulations.Sanganahalli BG, Thompson GJ, Parent M, Verhagen JV, Blumenfeld H, Herman P, Hyder F. PLoS One. 2022; 2022 May 6. PMID: 35522646.
Aerobic glycolysis imaging of epileptic foci during the inter-ictal period.Zhang M, Qin Q, Zhang S, Liu W, Meng H, Xu M, Huang X, Lin X, Lin M, Herman P, Hyder F, Stevens RC, Wang Z, Li B, Thompson GJ. EBioMedicine. 2022 May; 2022 Apr 15. PMID: 35436726.
The Stroke Preclinical Assessment Network: Rationale, Design, Feasibility, and Stage 1 Results.Lyden PD, Bosetti F, Diniz MA, Rogatko A, Koenig JI, Lamb J, Nagarkatti KA, Cabeen RP, Hess DC, Kamat PK, Khan MB, Wood K, Dhandapani K, Arbab AS, Leira EC, Chauhan AK, Dhanesha N, Patel RB, Kumskova M, Thedens D, Morais A, Imai T, Qin T, Ayata C, Boisserand LSB, Herman AL, Beatty HE, Velazquez SE, Diaz-Perez S, Sanganahalli BG, Mihailovic JM, Hyder F, Sansing LH, Koehler RC, Lannon S, Shi Y, Karuppagounder SS, Bibic A, Akhter K, Aronowski J, McCullough LD, Chauhan A, Goh A. Stroke. 2022 May; 2022 Mar 31. PMID: 35354299.
Reversibility of brain glucose kinetics in type 2 diabetes mellitus.Sanchez-Rangel E, Gunawan F, Jiang L, Savoye M, Dai F, Coppoli A, Rothman DL, Mason GF, Hwang JJ. Diabetologia. 2022 May; 2022 Mar 5. PMID: 35247067.
Glucose sparing by glycogenolysis (GSG) determines the relationship between brain metabolism and neurotransmission.Rothman DL, Dienel GA, Behar KL, Hyder F, DiNuzzo M, Giove F, Mangia S. J Cereb Blood Flow Metab. 2022 May; 2022 Jan 7. PMID: 34994222.
High-resolution relaxometry-based calibrated fMRI in murine brain: Metabolic differences between awake and anesthetized states.Xu M, Bo B, Pei M, Chen Y, Shu CY, Qin Q, Hirschler L, Warnking JM, Barbier EL, Wei Z, Lu H, Herman P, Hyder F, Liu ZJ, Liang Z, Thompson GJ. J Cereb Blood Flow Metab. 2022 May; 2021 Dec 15. PMID: 34910894.
High-resolution pH imaging using ratiometric chemical exchange saturation transfer combined with biosensor imaging of redundant deviation in shifts featuring paramagnetic DOTA-tetraglycinate agents.Mihailovic JM, Huang Y, Walsh JJ, Khan MH, Mishra SK, Samuels S, Hyder F, Coman D. NMR Biomed. 2022 May; 2021 Nov 27. PMID: 34837412.
Prefrontal Glutamate Neurotransmission in PTSD: A Novel Approach to Estimate Synaptic Strength in Vivo in Humans.Averill LA, Jiang L, Purohit P, Coppoli A, Averill CL, Roscoe J, Kelmendi B, De Feyter HM, de Graaf RA, Gueorguieva R, Sanacora G, Krystal JH, Rothman DL, Mason GF, Abdallah CG. Chronic Stress (Thousand Oaks). 2022 Jan-Dec; 2022 Apr 11. PMID: 35434443.
Ethnic and sex differences in hepatic lipid content and related cardiometabolic parameters in lean individuals.Petersen KF, Dufour S, Li F, Rothman DL, Shulman GI. JCI Insight. 2022 Apr 8; 2022 Apr 8. PMID: 35167495.
From a Demand-Based to a Supply-Limited Framework of Brain Metabolism.Herculano-Houzel S, Rothman DL. Front Integr Neurosci. 2022; 2022 Apr 1. PMID: 35431822.
MR spectroscopy frequency and phase correction using convolutional neural networks.Ma DJ, Le HA, Ye Y, Laine AF, Lieberman JA, Rothman DL, Small SA, Guo J. Magn Reson Med. 2022 Apr; 2021 Dec 21. PMID: 34931715.
Comparison of metabolic and immunologic responses to transarterial chemoembolization with different chemoembolic regimens in a rabbit VX2 liver tumor model.Doemel LA, Santana JG, Savic LJ, Gaupp FML, Borde T, Petukhova-Greenstein A, Kucukkaya AS, Schobert IT, Hamm CA, Gebauer B, Walsh JJ, Rexha I, Hyder F, Lin M, Madoff DC, Schlachter T, Chapiro J, Coman D. Eur Radiol. 2022 Apr; 2021 Oct 31. PMID: 34718844.
Correction to: Reevaluation of Astrocyte‑Neuron Energy Metabolism with Astrocyte Volume Fraction Correction: Impact on Cellular Glucose Oxidation Rates, Glutamate-Glutamine Cycle Energetics, Glycogen Levels and Utilization Rates vs. Exercising Muscle, and Na(+)/K(+) Pumping Rates.Dienel GA, Rothman DL. Neurochem Res. 2022 Mar. PMID: 35044619.
Comparison of Lanthanide Macrocyclic Complexes as (23)Na NMR Sensors.Khan MH, Mishra SK, Zakaria ABM, Mihailović JM, Coman D, Hyder F. Anal Chem. 2022 Feb 8; 2022 Jan 24. PMID: 35073049.
Dysregulated proton and sodium gradients highlight cancer invasion and proliferation.Hyder F, Khan MH. Transl Oncol. 2022 Feb; 2021 Dec 9. PMID: 34896853.
Imaging effective oxygen diffusivity in the human brain with multiparametric magnetic resonance imaging.Kufer J, Preibisch C, Epp S, Göttler J, Schmitzer L, Zimmer C, Hyder F, Kaczmarz S. J Cereb Blood Flow Metab. 2022 Feb; 2021 Sep 30. PMID: 34590895.
A High-Performance Gamma Spectrometer for Unmanned Systems Based on Off-the-Shelf Components.Chierici A, Malizia A, Di Giovanni D, Ciolini R, d'Errico F. Sensors (Basel). 2022 Jan 29; 2022 Jan 29. PMID: 35161824.
Cortical GABA levels are reduced in young adult binge drinkers: Association with recent alcohol consumption and sex.Marinkovic K, Alderson Myers AB, Arienzo D, Sereno MI, Mason GF. Neuroimage Clin. 2022; 2022 Jun 20. PMID: 35753236.
Extracellular pH Mapping as Therapeutic Readout of Drug Delivery in Glioblastoma.Walsh JJ, Hyder F. Methods Mol Biol. 2022. PMID: 35094344.
Effectiveness of a UVC air disinfection system for the HVAC of an ICU.de Souza SO, Cardoso AA Jr, Sarmento ASC, d'Errico F. Eur Phys J Plus. 2022; 2021 Dec 18. PMID: 34956809.
Novel approaches to estimate prefrontal synaptic strength in vivo in humans: of relevance to depression, schizophrenia, and ketamine.Abdallah CG, Mason GF. Neuropsychopharmacology. 2022 Jan. PMID: 34341492.

2021

Supraspinal Sensorimotor and Pain-Related Reorganization after a Hemicontusion Rat Cervical Spinal Cord Injury.Sanganahalli BG, Chitturi J, Herman P, Elkabes S, Heary R, Hyder F, Kannurpatti SS. J Neurotrauma. 2021 Dec. PMID: 34714150.
Deuterium metabolic imaging in the human brain at 9.4 Tesla with high spatial and temporal resolution.Ruhm L, Avdievich N, Ziegs T, Nagel AM, De Feyter HM, de Graaf RA, Henning A. Neuroimage. 2021 Dec 1; 2021 Oct 9. PMID: 34637905.
Renal plasticity revealed through reversal of polycystic kidney disease in mice.Dong K, Zhang C, Tian X, Coman D, Hyder F, Ma M, Somlo S. Nat Genet. 2021 Dec; 2021 Oct 11. PMID: 34635846.
Variations of Brain Functional Connectivity in Alcohol-Preferring and Non-Preferring Rats with Consecutive Alcohol Training or Acute Alcohol Administration.Liu Y, Nie B, Liu T, Zheng N, Liu Z, Shan B, Jiang L, Manyande A, Li X, Xu F, Wang J. Brain Sci. 2021 Nov 7; 2021 Nov 7. PMID: 34827473.
Small loci of astroglial glutamine synthetase deficiency in the postnatal brain cause epileptic seizures and impaired functional connectivity.Farina MG, Sandhu MRS, Parent M, Sanganahalli BG, Derbin M, Dhaher R, Wang H, Zaveri HP, Zhou Y, Danbolt NC, Hyder F, Eid T. Epilepsia. 2021 Nov; 2021 Sep 18. PMID: 34536233.
In vivo evidence of differential frontal cortex metabolic abnormalities in progressive and relapsing-remitting multiple sclerosis.Swanberg KM, Prinsen H, DeStefano K, Bailey M, Kurada AV, Pitt D, Fulbright RK, Juchem C. NMR Biomed. 2021 Nov; 2021 Jul 28. PMID: 34318959.
Preimplantation factor modulates oligodendrocytes by H19-induced demethylation of NCOR2.Spinelli M, Boucard C, Ornaghi S, Schoeberlein A, Irene K, Coman D, Hyder F, Zhang L, Haesler V, Bordey A, Barnea E, Paidas M, Surbek D, Mueller M. JCI Insight. 2021 Oct 22; 2021 Oct 22. PMID: 34676826.
Deuterium Metabolic Imaging of the Healthy and Diseased Brain.Straathof M, Meerwaldt AE, De Feyter HM, de Graaf RA, Dijkhuizen RM. Neuroscience. 2021 Oct 15; 2021 Jan 22. PMID: 33493618.
Two transition states of the glycogen shunt and two steady states of gene expression support metabolic flexibility and the Warburg effect in cancer.Rothman DL, Shulman RG. Neoplasia. 2021 Sep; 2021 Jul 21. PMID: 34303218.
Cell-type specific modulation of NMDA receptors triggers antidepressant actions.Pothula S, Kato T, Liu RJ, Wu M, Gerhard D, Shinohara R, Sliby AN, Chowdhury GMI, Behar KL, Sanacora G, Banerjee P, Duman RS. Mol Psychiatry. 2021 Sep; 2020 Jun 2. PMID: 32488125.
(1)H Magnetic Resonance Spectroscopy to Understand the Biological Basis of ALS, Diagnose Patients Earlier, and Monitor Disease Progression.Caldwell S, Rothman DL. Front Neurol. 2021; 2021 Aug 27. PMID: 34512519.
Imaging Hallmarks of the Tumor Microenvironment in Glioblastoma Progression.Walsh JJ, Parent M, Akif A, Adam LC, Maritim S, Mishra SK, Khan MH, Coman D, Hyder F. Front Oncol. 2021; 2021 Aug 26. PMID: 34513675.
Analysis of the time course of COVID-19 cases and deaths from countries with extensive testing allows accurate early estimates of the age specific symptomatic CFR values.Rothman JE, Eidelberg D, Rothman SL, Holford TR, Rothman DL. PLoS One. 2021; 2021 Aug 18. PMID: 34407073.
Simultaneous Recording of the Uptake and Conversion of Glucose and Choline in Tumors by Deuterium Metabolic Imaging.Veltien A, van Asten J, Ravichandran N, de Graaf RA, De Feyter HM, Oosterwijk E, Heerschap A. Cancers (Basel). 2021 Aug 10; 2021 Aug 10. PMID: 34439188.
Author Correction: Simultaneous cortex-wide fluorescence Ca(2+) imaging and whole-brain fMRI.Lake EMR, Ge X, Shen X, Herman P, Hyder F, Cardin JA, Higley MJ, Scheinost D, Papademetris X, Crair MC, Constable RT. Nat Methods. 2021 Jul. PMID: 34163088.
NMR visibility of deuterium-labeled liver glycogen in vivo.De Feyter HM, Thomas MA, Behar KL, de Graaf RA. Magn Reson Med. 2021 Jul; 2021 Feb 15. PMID: 33590529.
Diffusion weighted imaging as a biomarker of retinoic acid induced myelomeningocele.Maassel N, Farrelly J, Coman D, Freedman-Weiss M, Ahle S, Ullrich S, Yung N, Hyder F, Stitelman D. PLoS One. 2021; 2021 Jun 30. PMID: 34191842.
Medulloblastoma uses GABA transaminase to survive in the cerebrospinal fluid microenvironment and promote leptomeningeal dissemination.Martirosian V, Deshpande K, Zhou H, Shen K, Smith K, Northcott P, Lin M, Stepanosyan V, Das D, Remsik J, Isakov D, Boire A, De Feyter H, Hurth K, Li S, Wiemels J, Nakamura B, Shao L, Danilov C, Chen T, Neman J. Cell Rep. 2021 Jun 29. PMID: 34192534.
Hydrogels for Three-Dimensional Ionizing-Radiation Dosimetry.Marrale M, d'Errico F. Gels. 2021 Jun 21; 2021 Jun 21. PMID: 34205640.
Publisher Correction: Imaging the transmembrane and transendothelial sodium gradients in gliomas.Khan MH, Walsh JJ, Mihailović JM, Mishra SK, Coman D, Hyder F. Sci Rep. 2021 Jun 8; 2021 Jun 8. PMID: 34103626.