Endogenous contrast blood flow imaging in embryonic hearts using hemoglobin contrast subtraction angiography.
Deniz E, Jonas S, Khokha M, Choma MA. Endogenous contrast blood flow imaging in embryonic hearts using hemoglobin contrast subtraction angiography. Optics Letters 2012, 37: 2979-81. PMID: 22825198, PMCID: PMC3881542, DOI: 10.1364/ol.37.002979.Peer-Reviewed Original ResearchConceptsCongenital heart diseaseBiomechanical phenotypingSmall animal modelsMicroangiography techniqueCardiac dysfunctionEmbryonic heartHeart diseaseCardiac performanceEndogenous hemoglobin contrastContrast angiographyBlood flowCardioactive drugsAnimal modelsSubtraction angiographyVivo assessmentFunctional optical imagingHemoglobin contrastMalformed heartsAngiographyFlow imagingHeartPhysiological responsesImagingDysfunctionPhenotyping