2023
Defining the Age of Young Ischemic Stroke Using Data-Driven Approaches
Abedi V, Lambert C, Chaudhary D, Rieder E, Avula V, Hwang W, Li J, Zand R. Defining the Age of Young Ischemic Stroke Using Data-Driven Approaches. Journal Of Clinical Medicine 2023, 12: 2600. PMID: 37048683, PMCID: PMC10095415, DOI: 10.3390/jcm12072600.Peer-Reviewed Original ResearchElectronic health recordsIschemic strokeMale patientsYoung strokeOptimal ageYoung ischemic strokePatterns of comorbidityDifferent comorbidity patternsClinical profileFemale patientsSecond approachStroke cohortIS cohortPatient pairsComorbidity patternsPatientsAge groupsFirst approachFuture validation studiesDifferent agesHealth recordsStrokeAgeComorbiditiesSex groups
2021
“Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review
Lambert C, Olulana O, Bailey-Davis L, Abedi V, Zand R. “Lessons Learned” Preventing Recurrent Ischemic Strokes through Secondary Prevention Programs: A Systematic Review. Journal Of Clinical Medicine 2021, 10: 4209. PMID: 34575320, PMCID: PMC8471819, DOI: 10.3390/jcm10184209.Peer-Reviewed Original ResearchRecurrent ischemic strokeSecondary prevention programsIschemic strokePrevention programsControl blood pressureSupervised exercise programVascular risk factorsSignificant healthcare burdenTransitions of careShort-term effectivenessGoogle Scholar databasesLow-resource settingsLong-term effectivenessCurrent prevention programsLiterature search strategyRecurrent strokeDosage titrationBlood pressureExercise programHealthcare burdenRisk factorsFull-text analysisCare plansSystematic reviewScholar databasesSecond-Generation Antipsychotic Use in Pediatric Emergency Medicine.
Lambert C, Panagiotopoulos C, Davidson J, Goldman RD. Second-Generation Antipsychotic Use in Pediatric Emergency Medicine. Pediatric Emergency Care 2021, 37: 161-164. PMID: 33651760, DOI: 10.1097/pec.0000000000002387.Peer-Reviewed Original ResearchConceptsEmergency departmentSecond-generation antipsychotic prescriptionsPediatric emergency department providersPediatric emergency departmentEmergency department providersNumber of patientsType 2 diabetesGeneration antipsychotic useMental health complaintsRapid weight gainMental health conditionsPediatric emergency medicineCardiovascular complicationsMetabolic complicationsAntipsychotic prescriptionsGlucose intoleranceMetabolic syndromeCentral adiposityAntipsychotic usePrimary carePsychiatric servicesHealth complaintsWeight gainHealth conditionsSignificant riskTrends in ischemic stroke outcomes in a rural population in the United States
Chaudhary D, Khan A, Shahjouei S, Gupta M, Lambert C, Avula V, Schirmer C, Holland N, Griessenauer C, Azarpazhooh M, Li J, Abedi V, Zand R. Trends in ischemic stroke outcomes in a rural population in the United States. Journal Of The Neurological Sciences 2021, 422: 117339. PMID: 33592506, DOI: 10.1016/j.jns.2021.117339.Peer-Reviewed Original ResearchConceptsPrior ischemic strokeIschemic stroke patientsIschemic stroke recurrenceChronic kidney diseaseCause mortalityStroke recurrenceStroke mortality ratesIschemic strokeStroke patientsMortality rateHeart failureAtrial fibrillationKidney diseaseRisk factorsHazards modelConsecutive ischemic stroke patientsCox proportional hazards modelOne-yearOne-year recurrenceIschemic stroke outcomeRetrospective cohort studyCause mortality ratesCause-specific hazards modelPrevalent risk factorsElectronic health record data
2020
EPID-08. FINDING THE NEEDLE IN THE HAY STACK – POPULATION-BASED STUDY OF PREDIAGNOSTIC SYMPTOMATIC INTERVAL IN CHILDREN WITH CNS TUMORS
Lambert C, Goldman R, Cochrane D, Dahiya A, Mah H, Buttar A, Cheng S. EPID-08. FINDING THE NEEDLE IN THE HAY STACK – POPULATION-BASED STUDY OF PREDIAGNOSTIC SYMPTOMATIC INTERVAL IN CHILDREN WITH CNS TUMORS. Neuro-Oncology 2020, 22: iii320-iii320. PMCID: PMC7715968, DOI: 10.1093/neuonc/noaa222.194.Peer-Reviewed Original ResearchPosterior fossa tumorsCNS tumorsFossa tumorsCentral nervous system tumorsHealthcare provider visitsPrediagnostic symptomatic intervalRetrospective chart reviewFirst symptom onsetPresence of metastasesSymptoms of ataxiaPopulation-based studyComplete medical recordsLarge pediatric hospitalNervous system tumorsHealth care providersMedian total timePost-treatment relapseSymptomatic intervalProvider visitsChart reviewCNS tumorSymptom onsetSupratentorial tumorsMedian timePediatric hospitalAlexithymia in People With Recurrent Suicide Attempts
Bergmans Y, Guimond T, Lambert C, McInerney S, O'Brien K. Alexithymia in People With Recurrent Suicide Attempts. Crisis 2020, 42: 425-433. PMID: 33241742, DOI: 10.1027/0227-5910/a000738.Peer-Reviewed Original ResearchFinding the Needle in the Hay Stack: Population-based Study of Prediagnostic Symptomatic Interval in Children With CNS Tumors
Goldman RD, Cochrane DD, Dahiya A, Mah H, Buttar A, Lambert C, Cheng S. Finding the Needle in the Hay Stack: Population-based Study of Prediagnostic Symptomatic Interval in Children With CNS Tumors. Journal Of Pediatric Hematology/Oncology 2020, 43: e1093-e1098. PMID: 33235150, DOI: 10.1097/mph.0000000000002012.Peer-Reviewed Original ResearchConceptsPopulation-based studyCNS tumorsHealth care provider visitsCentral nervous system tumorsPrediagnostic symptomatic intervalRetrospective chart reviewSymptoms of ataxiaNervous system tumorsHealth care providersYears of ageSymptomatic intervalProvider visitsChart reviewPediatric centersMedian timeEducation of familiesDiagnostic challengeMedical recordsSystem tumorsChildren 0Devastating diagnosisPosterior fossaCare providersFirst symptomsAverage ageSex disparity in long-term stroke recurrence and mortality in a rural population in the United States
Lambert C, Chaudhary D, Olulana O, Shahjouei S, Avula V, Li J, Abedi V, Zand R. Sex disparity in long-term stroke recurrence and mortality in a rural population in the United States. Therapeutic Advances In Neurological Disorders 2020, 13: 1756286420971895. PMID: 33414844, PMCID: PMC7750897, DOI: 10.1177/1756286420971895.Peer-Reviewed Original ResearchRecurrent ischemic strokeIschemic stroke patientsIschemic stroke recurrenceCause mortalityIschemic strokeStroke recurrenceComposite outcomeStroke patientsRisk factorsAdult ischemic stroke patientsConsecutive ischemic stroke patientsKaplan-Meier estimator curvesLong-term stroke recurrenceCox proportional hazard ratiosTraditional vascular risk factorsChronic kidney diseaseIndependent risk factorPeripheral vascular diseasePoor stroke outcomesProportional hazard ratiosVascular risk factorsChronic lung diseaseRural populationHazard ratioStroke outcome
2018
Pain management for children needing laceration repair.
Lambert C, Goldman RD. Pain management for children needing laceration repair. Canadian Family Physician 2018, 64: 900-902. PMID: 30541804, PMCID: PMC6371869.Peer-Reviewed Original ResearchContrôle de la douleur lors de la réparation d’une lacération chez l’enfant.
Lambert C, Goldman R. Contrôle de la douleur lors de la réparation d’une lacération chez l’enfant. Canadian Family Physician 2018, 64: e526-e528. PMID: 30541817, PMCID: PMC6371881.Peer-Reviewed Original ResearchSecond-generation antipsychotics in children: Risks and monitoring needs.
Lambert C, Panagiotopoulos C, Davidson J, Goldman RD. Second-generation antipsychotics in children: Risks and monitoring needs. Canadian Family Physician 2018, 64: 660-662. PMID: 30209096, PMCID: PMC6135131.Peer-Reviewed Original ResearchConceptsSide effectsSecond-generation antipsychotic treatmentSafety of antipsychoticsMetabolic side effectsSecond-generation antipsychoticsUse of SGAsEfficacy of treatmentPotential side effectsQuality of lifeAdjunctive metforminPediatric patientsMale patientsAntipsychotic treatmentFamily physiciansPhysical activityPatient's motherTherapeutic effortsHealthy eatingPatientsWeight gainSGAFamily practiceChildren guidelinesCanadian AlliancePotential roleAntipsychotiques de deuxième génération chez l’enfant: Risques et exigences en matière de surveillance.
Lambert C, Panagiotopoulos C, Davidson J, Goldman R. Antipsychotiques de deuxième génération chez l’enfant: Risques et exigences en matière de surveillance. Canadian Family Physician 2018, 64: 663-666. PMID: 30209097, PMCID: PMC6135139.Peer-Reviewed Original ResearchAnhedonia in depression and schizophrenia: A transdiagnostic challenge
Lambert C, Da Silva S, Ceniti AK, Rizvi SJ, Foussias G, Kennedy SH. Anhedonia in depression and schizophrenia: A transdiagnostic challenge. CNS Neuroscience & Therapeutics 2018, 24: 615-623. PMID: 29687627, PMCID: PMC6489811, DOI: 10.1111/cns.12854.Peer-Reviewed Original ResearchPresentation and Neurobiology of Anhedonia in Mood Disorders: Commonalities and Distinctions.
Rizvi SJ, Lambert C, Kennedy S. Presentation and Neurobiology of Anhedonia in Mood Disorders: Commonalities and Distinctions. Current Psychiatry Reports 2018, 20: 13. PMID: 29520717, DOI: 10.1007/s11920-018-0877-z.Peer-Reviewed Original Research
2005
Understanding central venous catheter use among ESRD patients: a network 1 study.
Troidle L, Ginsberg J, Hill C, Kitsen J, Lambert C, Walworth C. Understanding central venous catheter use among ESRD patients: a network 1 study. Nephrology News & Issues 2005, 19: 72, 74-5. PMID: 16270741.Peer-Reviewed Original Research
2002
Prevalence of protein malnutrition in children maintained on peritoneal dialysis
Brem A, Lambert C, Hill C, Kitsen J, Shemin D. Prevalence of protein malnutrition in children maintained on peritoneal dialysis. Pediatric Nephrology 2002, 17: 527-530. PMID: 12172768, DOI: 10.1007/s00467-002-0886-2.Peer-Reviewed Original ResearchConceptsLow serum albuminProtein catabolic rateEnd-stage renal diseasePeritoneal dialysisProtein malnutritionEvidence-based treatment guidelinesMorbidity/mortalityAdult HD patientsDietary protein intakeESRD patientsRenal diseaseSerum albuminTreatment guidelinesHD patientsMean ageSurrogate markerOutcome measuresHemodialysisProtein intakeCatabolic rateNutritional statusGreater riskPatientsPrevalenceData collection period
2001
Clinical morbidity in pediatric dialysis patients: data from the Network 1 Clinical Indicators Project
Brem A, Lambert C, Hill C, Kitsen J, Shemin D. Clinical morbidity in pediatric dialysis patients: data from the Network 1 Clinical Indicators Project. Pediatric Nephrology 2001, 16: 854-857. PMID: 11685588, DOI: 10.1007/s004670100706.Peer-Reviewed Original ResearchConceptsNumber of hospitalizationsDialysis adequacy indicesHealth Care Financing AdministrationPeritoneal dialysisAntihypertensive medicationsDialysis patientsEnd-stage renal disease patientsStage renal disease patientsRenal disease patientsPediatric dialysis patientsType of dialysisDegree of anemiaKt/VLeast part timeClinical morbidityHD patientsSerum ferritinPD patientsEPO dosagePatient morbidityDisease patientsDialysis adequacySerum ironMorbidity dataClinical data
2000
First hemodialysis access selection varies with patient acuity.
Friedman A, Walworth C, Meehan C, Wander H, Shemin D, DeSoi W, Kitsen J, Hill C, Lambert C, Mesler D. First hemodialysis access selection varies with patient acuity. Advances In Kidney Disease And Health 2000, 7: s4-10. PMID: 11053581.Peer-Reviewed Original ResearchMeSH KeywordsAcute Kidney InjuryAgedArteriovenous Shunt, SurgicalBlood Vessel ProsthesisCatheters, IndwellingCenters for Medicare and Medicaid Services, U.S.FemaleHumansKidney Failure, ChronicMaleMiddle AgedPatient SelectionRenal DialysisSeverity of Illness IndexTotal Quality ManagementUnited StatesConceptsEnd-stage renal diseaseQuality improvement projectInitial hemodialysis accessNew ESRD patientsIncident dialysis patientsPermanent vascular accessMonths of dialysisVascular access selectionQuality improvement guidelinesIncident patientsDialysis requirementESRD patientsRenal insufficiencyDialysis patientsRenal diseasePatient's courseHemodialysis accessPatient groupVascular accessUnknown patientsPatient acuityPatientsClinical groupsFistulaCare qualityOutcome data on pediatric dialysis patients from the end-stage renal disease Clinical Indicators Project
Brem A, Lambert C, Hill C, Kitsen J, Shemin D. Outcome data on pediatric dialysis patients from the end-stage renal disease Clinical Indicators Project. American Journal Of Kidney Diseases 2000, 36: 310-317. PMID: 10922309, DOI: 10.1053/ajkd.2000.8975.Peer-Reviewed Original ResearchConceptsKt/VWeekly erythropoietin doseHD patientsPD patientsAlbumin levelsPeritoneal dialysisErythropoietin doseDialysis adequacySerum albumin levelPediatric dialysis patientsDegree of anemiaErythropoietin dosingChronic dialysisErythropoietin dosageAnemia managementDialysis patientsPatient ageOutcome dataPatientsHematocrit valuesAlbumin lossPatient sizeSmall childrenIndicators ProjectStrong inverse relationshipResidual Renal Function in a Large Cohort of Peritoneal Dialysis Patients: Change over Time, Impact on Mortality and Nutrition
Shemin D, Bostom A, Lambert C, Hill C, Kitsen J, Kliger A. Residual Renal Function in a Large Cohort of Peritoneal Dialysis Patients: Change over Time, Impact on Mortality and Nutrition. Advances In Peritoneal Dialysis 2000, 20: 439-444. PMID: 11007376, DOI: 10.1177/089686080002000411.Peer-Reviewed Original ResearchConceptsWeekly renal Kt/VRenal Kt/VResidual renal functionSerum albumin levelRenal creatinine clearanceKt/VKt/V ureaPeritoneal dialysis patientsCreatinine clearanceRenal functionPD patientsAlbumin levelsSolute clearanceDialysis patientsRenal clearanceTotal Kt/V ureaNutritional statusMean serum albumin levelTotal creatinine clearanceGood nutritional statusDiabetic statusCCR groupDialysis unitsLarge cohortPatients