Featured Publications
Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption
Bond CW, Trinko R, Foscue E, Furman K, Groman SM, Taylor JR, DiLeone RJ. Medial Nucleus Accumbens Projections to the Ventral Tegmental Area Control Food Consumption. Journal Of Neuroscience 2020, 40: 4727-4738. PMID: 32354856, PMCID: PMC7294796, DOI: 10.1523/jneurosci.3054-18.2020.Peer-Reviewed Original ResearchConceptsControl food intakeNAc projectionsFood intakeAccumbens projectionsLateral hypothalamusMesolimbic circuitsFood consumptionNucleus accumbens projectionsFood-seeking behaviorNAC controlVTA pathwayInhibitory projectionsMale miceNAc shellOptogenetic activationFiber photometryOptogenetic inhibitionPermissive rolePharmacological studiesDrug rewardVTAConsummatory behaviorIntakeAdaptive inhibitionNeural activity
2014
Optogenetic inhibition of neurons by internal light production
Land BB, Brayton CE, Furman KE, LaPalombara Z, DiLeone RJ. Optogenetic inhibition of neurons by internal light production. Frontiers In Behavioral Neuroscience 2014, 8: 108. PMID: 24744708, PMCID: PMC3978322, DOI: 10.3389/fnbeh.2014.00108.Peer-Reviewed Original ResearchOptogenetic inhibitionAmphetamine-induced locomotor activityNeural activityLuciferase-expressing virusesSuppress neural activitySpecific molecular pathwaysAdeno-associated virusLuciferase miceNeuronal activityLocomotor activityNeural circuitsActivation/inhibitionAdministrationMolecular pathwaysFos activityDelivery of lightVivo optogeneticsInhibitionMiceAnimalsVirusLuciferaseOptogeneticsOptical fiberStriatum