2003
Recombinant Factor VIIa Improves Coagulopathy Caused by Liver Failure
Brown J, Emerick K, Brown D, Whitington P, Alonso E. Recombinant Factor VIIa Improves Coagulopathy Caused by Liver Failure. Journal Of Pediatric Gastroenterology And Nutrition 2003, 37: 268-272. DOI: 10.1002/j.1536-4801.2003.tb11993.x.Peer-Reviewed Original ResearchLiver failureFresh frozen plasmaProthrombin timeRFVIIa therapyFrozen plasmaFluid balanceImproved fluid balanceChronic liver failureRecombinant factor VIIaOutcome of treatmentMean prothrombin timeRFVIIa useRFVIIa treatmentClinical bleedingConsecutive patientsRetrospective reviewThrombotic eventsTraditional therapiesSustained improvementCoagulopathyPatientsImportant causeTherapyRFVIIaFactor VIIa
2002
Azathioprine Metabolite Measurements in the Treatment of Autoimmune Hepatitis in Pediatric Patients: A Preliminary Report
Rumbo C, Emerick K, Emre S, Shneider B. Azathioprine Metabolite Measurements in the Treatment of Autoimmune Hepatitis in Pediatric Patients: A Preliminary Report. Journal Of Pediatric Gastroenterology And Nutrition 2002, 35: 391-398. DOI: 10.1002/j.1536-4801.2002.tb07844.x.Peer-Reviewed Original ResearchPediatric patientsAZA metabolite levelsAzathioprine metabolite measurementsMedication-induced toxicityNormal TPMT levelsInflammatory bowel diseaseCohort of childrenThiopurine methyltransferase enzyme activityRoutine biochemical studiesPotential adverse effectsAutoimmune hepatitisAZA doseMedication toxicityTPMT levelsALT levelsSteroid requirementsBowel diseaseDose escalationStandard dosesMetabolite testingMean doseTherapeutic effectBlood samplesAzathioprinePatients