2005
BZR1 Is a Transcriptional Repressor with Dual Roles in Brassinosteroid Homeostasis and Growth Responses
He JX, Gendron JM, Sun Y, Gampala SS, Gendron N, Sun CQ, Wang ZY. BZR1 Is a Transcriptional Repressor with Dual Roles in Brassinosteroid Homeostasis and Growth Responses. Science 2005, 307: 1634-1638. PMID: 15681342, PMCID: PMC2925132, DOI: 10.1126/science.1107580.Peer-Reviewed Original ResearchMeSH KeywordsArabidopsisArabidopsis ProteinsBase SequenceBinding SitesChromatin ImmunoprecipitationDNA-Binding ProteinsFeedback, PhysiologicalGene Expression Regulation, PlantGenes, PlantGenes, ReporterHomeostasisLightMutationNuclear ProteinsOligonucleotide Array Sequence AnalysisPhenotypePlant Growth RegulatorsPlants, Genetically ModifiedPromoter Regions, GeneticRecombinant Fusion ProteinsRepressor ProteinsSignal TransductionSteroidsTranscription, GeneticConceptsBrassinosteroid homeostasisTranscriptional repressorCell surface receptor kinaseBR biosynthetic genesDevelopment of plantsGrowth responseBR homeostasisBR biosynthesisBiosynthetic genesBZR1Dual roleReceptor kinaseAdditional potential targetsGene expressionMicroarray analysisUnknown DNARepressorNormal growthHomeostasisPotential targetPhysiological studiesDephosphorylationBiosynthesisKinaseGenes
2002
The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis
He JX, Gendron JM, Yang Y, Li J, Wang ZY. The GSK3-like kinase BIN2 phosphorylates and destabilizes BZR1, a positive regulator of the brassinosteroid signaling pathway in Arabidopsis. Proceedings Of The National Academy Of Sciences Of The United States Of America 2002, 99: 10185-10190. PMID: 12114546, PMCID: PMC126645, DOI: 10.1073/pnas.152342599.Peer-Reviewed Original ResearchMeSH KeywordsArabidopsisArabidopsis ProteinsCalcium-Calmodulin-Dependent Protein KinasesDNA-Binding ProteinsGene Expression Regulation, PlantGlycogen Synthase Kinase 3Glycogen Synthase KinasesGreen Fluorescent ProteinsLuminescent ProteinsNuclear ProteinsPhosphorylationPhytosterolsPlants, Genetically ModifiedProtein KinasesSignal TransductionConceptsPositive regulatorBZR2/BES1Two-hybrid assayBZR1 proteinReceptor BRI1BZR1Proteasome machineryBrassinosteroidsBIN2 activityNegative regulatorBIN2Protein accumulationRegulatorNormal growthDephosphorylationProteasome inhibitorsAccumulationBES1BRI1ArabidopsisPhosphorylatesSteroid hormonesMG132YeastPhosphorylation