2024
Transmembrane pH gradient imaging in rodent glioma models
Mishra S, Santana J, Mihailovic J, Hyder F, Coman D. Transmembrane pH gradient imaging in rodent glioma models. NMR In Biomedicine 2024, 37: e5102. PMID: 38263680, PMCID: PMC10987279, DOI: 10.1002/nbm.5102.Peer-Reviewed Original ResearchNormal tissuesRodent glioma modelsGL261 gliomasU87 gliomasTumor microenvironmentPotential therapeutic targetGlioma modelTumor survivalExtracellular acidosisTumorMetabolic reprogrammingRegulate drug deliveryIntracellular pHRat brainExtracellular pHTherapeutic targetGliomaMouse brainDrug deliveryIntracellular milieuTransmembrane pH gradientBrainSubmillimeter resolutionTissueCells
2000
Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI
Xu F, Kida I, Hyder F, Shulman R. Assessment and discrimination of odor stimuli in rat olfactory bulb by dynamic functional MRI. Proceedings Of The National Academy Of Sciences Of The United States Of America 2000, 97: 10601-10606. PMID: 10973488, PMCID: PMC27071, DOI: 10.1073/pnas.180321397.Peer-Reviewed Original ResearchConceptsRat olfactory bulbOlfactory bulbFunctional MRIBlood oxygenation level-dependent (BOLD) functional MRILevel-dependent functional MRIReceptor cellsExternal plexiform layerOlfactory nerve layerEntire olfactory bulbSpatial activity patternsFunctional MRI resultsNerve layerPlexiform layerGlomerular layerMRI resultsOdor stimuliIAA exposureMRIActivity patternsExposureLonger exposureDifferent concentrationsDifferent subsetsBulbCells