Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration
Khosravi P, Zugman A, Amelio P, Winkler A, Pine D. Translating Big Data to Clinical Outcomes in Anxiety: Potential for Multimodal Integration. Current Psychiatry Reports 2022, 24: 841-851. PMID: 36469202, PMCID: PMC9931491, DOI: 10.1007/s11920-022-01385-6.Peer-Reviewed Original ResearchConceptsAnxiety disordersError Related NegativityPediatric anxiety disordersMost anxiety disordersDisorder treatment outcomesAnxious individualsNeural correlatesMultimodal integrationNeural markersGroup differencesResponse/outcomesAnxietyMultimodal dataCorrelatesTreatment responseTreatment outcomesDiverse relationsDisordersReviewThis reviewNegativityRecent FindingsRecent literatureRisk markersAdulthoodSuch workOutcomesStructural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis
Bas-Hoogendam J, Bernstein R, Benson B, Buss K, Gunther K, Pérez-Edgar K, Salum G, Jackowski A, Bressan R, Zugman A, Degnan K, Filippi C, Fox N, Henderson H, Tang A, Zeytinoglu S, Harrewijn A, Hillegers M, White T, van IJzendoorn M, Schwartz C, Felicione J, DeYoung K, Shackman A, Smith J, Tillman R, van den Berg Y, Cillessen A, Roelofs K, Tyborowska A, Hill S, Battaglia M, Tettamanti M, Dougherty L, Jin J, Klein D, Leung H, Avery S, Blackford J, Clauss J, Hayden E, Liu P, Vandermeer M, Goldsmith H, Planalp E, Nichols T, Thompson P, Westenberg P, van der Wee N, Groenewold N, Stein D, Winkler A, Pine D, Group E. Structural Brain Correlates of Childhood Inhibited Temperament: An ENIGMA-Anxiety Mega-analysis. Journal Of The American Academy Of Child & Adolescent Psychiatry 2022, 61: 1182-1188. PMID: 36038199, PMCID: PMC9434711, DOI: 10.1016/j.jaac.2022.04.023.Peer-Reviewed Original ResearchConceptsStructural brain correlatesSelf-report questionnairesTendency of individualsInhibited temperamentBehavioral inhibitionBrain correlatesUnfamiliar peopleDirect behavioral observationsEmotional tendencyTemperamentTemperament classificationEarly childhoodBehavioral observationsUnexpected eventsRetrospective levelsIndividualsUnfamiliarCorrelatesCaregiversTendencyRelateFirst yearChildhoodInfancyLife