2023
CT attenuation correction improves quantitative risk prediction by cardiac SPECT in obese patients
Feher A, Pieszko K, Shanbhag A, Lemley M, Bednarski B, Miller R, Huang C, Miras L, Liu Y, Sinusas A, Slomka P, Miller E. CT attenuation correction improves quantitative risk prediction by cardiac SPECT in obese patients. European Journal Of Nuclear Medicine And Molecular Imaging 2023, 51: 695-706. PMID: 37924340, DOI: 10.1007/s00259-023-06484-x.Peer-Reviewed Original ResearchMajor adverse cardiac eventsMyocardial perfusion imagingSPECT myocardial perfusion imagingMACE-free survivalObese patientsPrognostic valueSignificant incremental prognostic valueYale-New Haven HospitalLate coronary revascularizationStress total perfusion deficitAdverse cardiac eventsIncremental prognostic valueNonfatal myocardial infarctionComposite end pointCT myocardial perfusion imagingSuperior prognostic valueSPECT/CT myocardial perfusion imagingTotal perfusion deficitNew Haven HospitalCT attenuation correctionHighest ROC areaStress TPDCoronary revascularizationCardiac eventsPatient population
2021
Impact of age, sex, and cardiac size on the diagnostic performance of myocardial perfusion single-photon emission computed tomography: insights from the REFINE SPECT registry
Randazzo M, Elias P, Poterucha T, Sharir T, Fish M, Ruddy T, Kaufmann P, Sinusas A, Miller E, Bateman T, Dorbala S, Di Carli M, Berman D, Slomka P, Einstein A. Impact of age, sex, and cardiac size on the diagnostic performance of myocardial perfusion single-photon emission computed tomography: insights from the REFINE SPECT registry. European Heart Journal 2021, 42: ehab724.0254. DOI: 10.1093/eurheartj/ehab724.0254.Peer-Reviewed Original ResearchCoronary artery diseaseElderly patientsImpact of ageSingle photon emissionDiagnostic performanceYounger patientsFemale patientsCardiac sizeSPECT-MPILower EDVCardiac volumesObstructive coronary artery diseasePrediction of CADTomography myocardial perfusion imagingMyocardial perfusion single-photon emissionDiagnostic accuracyPerfusion single-photon emissionCardiac event rateStress total perfusion deficitReceiver-operating characteristic curveInvasive coronary angiographyEnd-diastolic volumeCardiac chamber sizeAlternative diagnostic modalityTotal perfusion deficit