Contact Info

Satinder Singh, PhD
Office Location
Sterling Hall of Medicine, B-Wing
333 Cedar Street, Ste Room SHM BE11A

New Haven, CT 06510
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Mailing Address
Cellular & Molecular Physiology333 Cedar Street, SHM B147
P.O. Box 208026

New Haven, CT 06520
Research Image 1

Conformational dynamics of LeuT, a neurotransmitter:sodium symporter, embedded in a nanoscale lipid bilayer (nanodisc), as assessed by hydrogen-deuterium exchange (HDX-MS) kinetics. LeuT is a prokaryotic homolog of the human dopamine and serotonin transporters, currently the primary protein targets of the lab. Individual figures from Adhikary et al, (2017) are overlaid onto an image of the synaptic cleft.