Christopher Van Dyck, MD

Professor of Psychiatry, Neurology, and Neuroscience; Director, Alzheimer's Disease Research Unit; Director, Yale Alzheimer's Disease Research Center; Director, Division of Aging and Geriatric Psychiatry

Departments & Organizations

Psychiatry: Alzheimer's Disease Research Unit | Division of Aging & Geriatric Psychiatry | Neuroscience Research Training Program (NRTP)

Alzheimer's Disease Research Center (ADRC)

Dorothy Adler Geriatric Assessment Center

Interdepartmental Neuroscience Program

Yale Combined Program in the Biological and Biomedical Sciences (BBS): Neuroscience: Neural Disorders

Yale Medicine

Office of Cooperative Research


Christopher H. van Dyck, MD, is Professor of Psychiatry, Neurology, and Neuroscience, Director, Division of Aging and Geriatric Psychiatry; Director of the Alzheimer's Disease Research Unit; Director, Yale Alzheimer's Disease Research Center

His research interests include therapeutic, neuroimaging and genetic studies of Alzheimer's disease (AD) and healthy cognitive aging. Dr. van Dyck is very active in AD therapeutic research. Since 1992 he has participated in 80+ multicenter clinical trials for AD and MCI and has authored several of the trial publications. He serves on the Steering Committees of the NIA Alzheimer's Disease Cooperative Study (ADCS) and Alzheimer's Disease Neuroimaging Initiative (ADNI). Dr. van Dyck’s other significant scholarly contributions include dopamine transporter imaging in healthy aging and the apolipoprotein E e4 Phenotype of AD. In 2005 he received the "Compassion and Cure" Award from the Alzheimer's Association.

Education & Training

MD Northwestern University (1984)
BA Yale University (1978)
Resident Yale-New Haven Hospital
Fellow Yale University School of Medicine
Board Certification AB of Psychiatry & Neurology, Psychiatry (1991)

Honors & Recognition

  • Best Doctors in New York (Top 2%), as Featured in New York MagazineCastle Connolly (2005, 2014)

  • “Compassion and Cure” AwardAlzheimer’s Association (2005)

  • Junior Investigator AwardAmerican Association for Geriatric Psychiatry (1996)

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Contact Info

Christopher Van Dyck, MD
Patient Care Locations
Yale Alzheimer's Disease Research Unit1 Church Street, Ste Suite 600
New Haven, CT 06510
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Adler Geriatric Assessment Center874 Howard Avenue
New Haven, CT 06519
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Mailing Address
PsychiatryYale University School of Medicine
One Church Street

New Haven, CT 06510

Alzheimer's Disease Research Unit

Research Image 1

Frequency of psychosis by ApoE e4 carrier status and dementia severity. Mini Mental State Examination (MMSE) score was used to classify AD patients as mild (MMSE>19, n=103), moderate (MMSE=12-19, n=121), or severe (MMSE<12, n=42). Separate multiple logistic regression analyses were performed for each severity category, with presence of psychosis as dependent variable and the following independent variables (in addition to e4 carrier status): age, sex, educational attainment, and MMSE. *Only at the severe stage was the presence of e4 significantly associated with psychosis (odds ratio [OR]=16.61, 95% CI=2.11-130.51, P=.008). (From Zdanys KF , et al. 2007.)