Associate Professor of Microbial Pathogenesis and of Immunobiology; Member, Yale Systems Biology Institute; Investigator, Howard Hughes Medical Institute
Structural Analysis of Immune System Receptors and Effectors
There is a growing interest in using structural approaches to understand the function of key molecules of the immune response. For example, a major effort is devoted towards understanding how the Toll-like receptors, despite their similarity in extracellular-ligand recognition regions, are able to specifically recognize such a wide variety of pathogen associated molecular patterns (PAMPS). Another effort is aimed at understanding the mechanism of APOBEC enzymes in controlling viruses such as HIV.
Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute
Arthur H. and Isabel Bunker Professor of Medicine (Hematology) and Professor of Immunobiology; Director, Center of Molecular and Cellular Oncology
Assistant Professor of Immunobiology
Waldemar Von Zedtwitz Professor of Immunobiology and Professor of Molecular Biophysics and Biochemistry; Chair, Immunobiology