Genetics Clinical Grand Rounds: Molecular Genetics of Polycystic Kidney and Liver Diseases

Program Objective(s):

1 To understand the molecular genetic bases of human autosomal dominant polycystic diseases affecting the kidney and liver.

2. To understand the role of the polycystin proteins and primary cilia in the pathogenesis of polycystic kidney and liver diseases based on preclinical models.

3. To understand the potential for therapy in polycystic kidney and liver diseases based on studies in preclinical models.