The amyloid plaque indicator fluor, thioflavin T (shown in orange), intercalated between beta sheets of the protein, beta-2-microglobulin. Image from the Miranker lab.
The Biochemistry, Quantitative Biology, Biophysics and Structural Biology (BQBS) Track provides students with experimental, theoretical, and computational research training across a broad range of scales, from molecules to cells to whole organisms. Our approaches encompass a full range of modern disciplines including biochemistry and molecular biology, biophysics, chemistry, cell biology, genomics and proteomics, computational biology, and structural biology.
Recent revolutionary developments in modern biology have greatly advanced the diverse interests of our faculty. Technical advances in X-ray crystallography, cryo-electron microscopy (cryo-EM), live imaging, single molecule studies, next-generation sequencing, and mass spectrometry have led to a wealth of quantitative data for addressing long-standing biology questions. The integration of experimental data with computer modeling has stimulated productive collaborations among the disciplines of biology, chemistry, physics, and engineering. Our students will thus have a broad training in experimental and quantitative skills to perform in-depth mechanistic studies of diverse biological processes.Students in this Track are expected to meet rigorous standards in their course work and research. Our mission is to impart the intellectual and practical skills needed to engage in biological research at the highest level. We believe this requires a combination of deep understanding of biology and chemistry and the application of quantitative methods and modeling. It is our goal to develop our students’ independence, creativity and rigor, while fostering their adventurousness. These are the attributes that will propel our trainees to be future leaders in their field.