Rotavirus; Typhoid Fever
Professor Pitzer uses mathematical models for the transmission dynamics of infectious diseases to understand patterns in the distribution of cases over time and space, and to predict the potential impact of interventions. By integrating epidemiological data analysis with concepts from disease ecology, she studies how characteristics of host-pathogen interactions affect the population-level spread of disease. Current projects include understanding the dynamics of rotavirus and the potential impact of vaccination in developing countries; evaluating strategies for controlling typhoid fever in endemic countries; and understanding how climatic factors influence the seasonality and spatiotemporal spread of RSV.
- Pitzer VE, Atkins KE, de Blasio BF, Lopman BA, Van Effelterre T, Edmunds WJ, Viboud C, Grenfell BT, Patel MM, Parashar UD (2012). Direct and indirect effects of rotavirus vaccination: Comparing predictions from transmission dynamic models. PLoS ONE. 7(8
- Lopman BA, Pitzer VE, Sarkar R, Gladstone B, Patel MM, Glasser JW, Gambhir M, Atchison C, Grenfell BT, Edmunds WJ, Kang G, Parashar UD (2012). Understanding reduced rotavirus vaccine efficacy in low socio-economic settings. PLoS ONE. 7(8): e41720.
- Pitzer VE, Basta NE (2012). Linking Data and Models: The Importance of Statistical Analyses to Inform Models for the Transmission Dynamics of Infections. Epidemiology. 23(4): 520-522.
- Pitzer VE, Patel MM, Lopman BA, Viboud C, Parashar UD, Grenfell BT (2011). Modeling rotavirus strain dynamics in developed countries to understand the potential impact of vaccination on genotype distributions. Proc Natl Acad Sci USA. 108(48): 19353-8.
- Pitzer VE, Viboud C, Lopman BA, Patel MM, Parashar UD, Grenfell BT (2011). Influence of Birth Rates and Transmission Rates on the Global Seasonality of Rotavirus Incidence. J Roy Soc Interface. 8(64): 1584-93.
- Shaman J, Pitzer VE, Viboud C, Grenfell BT, Lipsitch M (2010). Absolute Humidity and the Seasonal Onset of Influenza in the Continental US. PLoS Biology. 8(2): e1000316.
- Pitzer VE, Viboud C, Simonsen L, Steiner C, Panozzo CA, Alonso WJ, Miller MA, Glass RI, Glasser JW, Parashar UD, Grenfell BT (2009). Demographic Variability, Vaccination, and the Spatiotemporal Dynamics of Rotavirus. Science. 325(5938): 290-4.