Peter James Krause, MD

Senior Research Scientist in Epidemiology (Microbial Diseases), in Medicine (Infectious Diseases) and in Pediatrics (Infectious Disease) and Lecturer in Epidemiology (Microbial Diseases)

Research Interests

Babesiosis; Blood Transfusion; Epidemiology; Lyme Disease; Relapsing Fever; Borrelia burgdorferi; Infectious Disease Medicine; Organisms; Diseases

Research Organizations

School of Public Health: Epidemiology of Microbial Diseases: Vector-borne

Faculty Research

Infectious Diseases

Research Summary

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.

Specialized Terms: Vector borne diseases

Extensive Research Description

Dr. Krause’s research interests are in vector borne diseases including babesiosis, Lyme disease and Borrelia miyamotoi, a relapsing fever spirochete. Current projects include babesiosis and Lyme disease persistence, co-infection, and geographic expansion; the host immunologic response to Babesia microti; prevention of transmission of babesiosis through blood transfusion; and human infection with Borrelia miyamotoi.

Selected Publications

  • Transfusion transmitted babesiosis. Is it time to screen the blood supply? Levin A, Krause PJ. Transfusion transmitted babesiosis. Is it time to screen the blood supply? Curr Opin Hematol, in press
  • Coinfection by Ixodes tick-borne pathogens: Ecological, epidemiological, and clinical consequences. Diuk-Wasser M, Vannier E, Krause PJ. Coinfection by Ixodes tick-borne pathogens: Ecological, epidemiological, and clinical consequences. Trends in Parasitol. 2016;32:30-42.
  • Borrelia miyamotoi infection in nature and in humans. Krause PJ, Fish D, Narasimhan S, Barbour AG. Borrelia miyamotoi infection in nature and in humans. Clin Microbiol Infect. 2015;21:631-639.
  • Blood transfusion transmission of the tick-borne relapsing fever spirochete Borrelia miyamotoi in mice Krause PJ, Hendrickson J, Steeves T, Fish D. Transfusion 2015;55:593-7.
  • Babesiosis in China, an emerging threat.

    Vannier E and Krause PJ. Babesiosis in China, an emerging threat. Lancet Infect Dis 2015;15:137-9.

  • Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States.

    Krause PJ, Narasimhan S, Wormser GP, Barbour AG, Platonov AE, Brancato J, Lepore T, Dardick K, Mamula M, Rollend L, Steeves TK, Diuk-Wasser M, Usmani-Brown S, Williamson P, Sarksyan DS, Fikrig E, Fish D. Tick Borne Diseases Group. Borrelia miyamotoi sensu lato seroreactivity and seroprevalence in the northeastern United States. Emerging Infectious Diseases 2014;20:1183-90

  • Human babesiosis.

    Vannier E and Krause PJ. Human Babesiosis. New England Journal of Medicine 2012;366:2397-407

  • Preventing transfusion transmitted babesiosis: Preliminary experience of the first laboratory-based blood donor screening program.

    Young C, Chawla A, Berardi V, Padbury J, Skowron G, Krause PJ. Preventing transfusion transmitted babesiosis: Preliminary experience of the first laboratory-based blood donor screening program. Transfusion 2012;52:1523-29.

  • Human Infection with the relapsing fever spirochete Borrelia miyamotoi.

    Platonov AE, Karan LS, Kolyasnikova NM, Makhneva NA, Toporkova MG, Maleev VV, Fish D, Krause PJ. Human Infection with the relapsing fever spirochete Borrelia miyamotoi. Emerg Inf Dis, 2011,17:1816-1823.

  • Increasing health burden of human babesiosis in endemic sites.

    Krause PJ, McKay K, Gadbaw J, et al: Increasing health burden of human babesiosis in endemic sites. American Journal of Tropical Medicine and Hygiene 2003;68:431-6.

  • Atovaquone and azithromycin for the treatment of human babesiosis.

    Krause PJ, Lepore T, Sikand VK, et al. Atovaquone and azithromycin for the treatment of human babesiosis. New England Journal of Medicine 343:1454-1458, 2000

  • Persistent parasitemia following acute babesiosis.

    Krause PJ, Spielman A, Telford S, et al. Persistent parasitemia following acute babesiosis. New England Journal of Medicine, 339: 160-165, 1998

Edit this profile

Contact Info

Peter James Krause, MD
Office Location
Laboratory of Epidemiology and Public Health
60 College Street, Ste 604

New Haven, CT 06510
View on map...
Mailing Address
Yale School of Public HealthPO Box 208034
60 College Street

New Haven, CT 06520-8034

Curriculum Vitae