Andrew Thomas DeWan PhD, MPH
Assistant Professor of Epidemiology (Chronic Diseases)
Genetic epidemiology; Statistical genetics; Asthma; Preeclampsia; Sepsis
Family-specific genetic variants contributing to asthma susceptibility: 1R01HL116742, NIH/NHLBI, DeWan (PI), 01/15/13-12/31/17
Identification of associations between genetic factors and asthma that are modified by obesity: FA8650-13-2-6371, USAF/AFMC, DeWan (PI), 02/08/13 – 02/07/15
Fetal Genetic Contributions to Preeclampsia: 1R21HD070177, NIH/NICHD, Triche/DeWan (co-PIs), 04/01/12-03/31/14
Genome-wide association studies in patients with bacterial sepsis ‘GWASEPSIS’: Liaison Committee between the Central Norway Regional Health Authority (RHA) and the Norwegian University of Science and Technology (NTNU), Damas (PI), 06/01/12 – 06/01/13
Professor DeWan seeks to understand how variation in the human genome contributes to complex human diseases. Using high-throughput technologies, he conducts genome-wide association studies to map disease susceptibility loci. His work also emphasizes the development of methods that improve the way in which this information is interpreted and utilized by disease researchers. He is also interested in the role that the interaction between genetic and environmental factors plays on disease susceptibility. His past work mapping disease genes has led to the discovery of susceptibility loci for age-related macular degeneration, non-syndromic hearing loss, renal function and myopia. Current projects include a genetic study of childhood asthma in collaboration with the Yale Center for Perinatal, Pediatric and Environmental Epidemiology, a study of genetic factors predisposing women to develop preeclampsia during pregnancy in collaboration with researchers at Brown and Yale Universities, and a study of genetic susceptibility loci for sepsis in collaboration with investigators at the Norwegian University of Science and Technology.