The School of Public Health at Yale University (YSPH) provides leadership to protect and improve the health of the public. Through innovative research, policy analysis and education that draws upon multidisciplinary scholarship from across the graduate and professional programs, the school serves local, national and international communities with its knowledge and expertise.
YSPH works actively on many of today’s most pressing health issues. Research includes HIV/AIDS, air pollution and respiratory health, insect-borne diseases, health disparities, cancer epidemiology, global health systems, chronic diseases and genomics, among many others. Advances in these areas help to improve the lives of people locally, nationally and worldwide.
Commitment to global health is integral to both YSPH and the greater university. Following is a list of various research initiatives by School of Public Health faculty serving global health and other international needs.
Belarus, Georgia and Moldova
Using a combination of mathematical modeling techniques and traditional research methods for epidemiological analysis in order to control drug resistant tuberculosis.
Using mathematical modeling to understand the impact of vaccination on the incidence and distribution of genotypes causing rotavirus gastroenteritis.
Analyzing historical disease data from a nationwide bacterial surveillance system to understand interactions of respiratory viruses with different bacterial strains.
Estonia and Russia
Working with local partners on HIV risk reduction, especially among sex workers and people with addictions to drugs and alcohol.
Collaborating with the Ministry of Health and the health surveillance branch of the French government to promulgate the country’s first-ever national guidelines for routine HIV testing.
The role of aldehyde dehydrogenases, cytochrome P-450s and glutathione in metabolism and disease (specifically, alcohol-induced tissue injury, diabetes, gout and cancer).
The seasonal epidemic patterns of influenza over the past 90 years and the impacts of Iceland’s increasing global connections on the timing of the annual epidemics.
Study of association between obesity with increased prevalence of asthma in Norwegian adolescents.
A genomewide association study of patients admitted to the hospital with sepsis of bacteremia along with a set of controls drawn from the same source population to identify genetic variants.
Studying the persistence or loss of acquired antimicrobial-drug resistance in bacterial populations previously exposed to drug-selective pressure; reviewing mechanisms that promote or prevent the loss of resistance.
The Netherlands, Navajo/White Mountain Apache Tribes
Using surveillance tools to monitor the relationship between seasonal variations and pneumococcal disease among people in the Netherlands and the Navajo and White Mountain Apache populations.
The investigation of crystal structures of various aldehyde dehydrogenases, a group of enzymes that catalyze the oxidation of aldehydes, and using the results for drug discovery.
The Global Health Leadership Institute at Yale and the South Essex Partnership Foundation Trust created the Health and Social Care Leadership Program to help health care managers succeed in new financial and operational frameworks.
GHLI - Bradley, Nembhard, Cooper, Desai, Khoshnood
Methodological issues in the design, conduct, and analysis of clinical and large-population/epidemiologic studies. Design and sample size considerations for Phase IV studies are another active research area.
Central America, the Caribbean Islands, South America
Barbados, Puerto Rico, the U.S. Virgin Islands, Tobago and Trinidad
The Global Health Leadership Institute collaborates with The Eastern Caribbean Health Outcomes Research Network to study the risk factors and prevalence of non-communicable disease in the Eastern Caribbean.
GHLI - Bradley
Childhood violence and global health. As part of the Yale Global Health Leadership Institute Forums for Change program, colleagues at the Yale Child Study Center and in Brazil address the effect of violence on children.
Research and training in collaboration with Fiocruz, Brazil’s health ministry, to address infectious diseases in the favelas, including leptospirosis, dengue, bacterial meningitis and vaccine preventable diseases.
Collaborating with local scientists to better understand the interactions of pathogens that affect the residents of the Pau da Lima favela in Salvador, Brazil.
Brazil and Mexico
Leads the Latin America and Caribbean household food security measurement and serves as senior advisor to both the Brazilian and Mexican governments on the project.
Research and training to identify strategies and devise ways to interrupt the cycle of transmission and pathogenesis of leishmaniasis as well as to eventually develop a vaccine to stop the insect-borne disease.
Helped the island in its initial response to the spread of chikungunya, an infectious disease carried by the Asian tiger mosquito. Researchers are collecting and modeling data on the disease’s prevalence and trajectory.
Life-course exposures and diet and their effects on epigenetics, maturation and metabolic syndrome in collaboration with colleagues at the Mexico City Children’s Center.
Using a combination of mathematical modeling techniques and traditional methods for epidemiological analysis to better control drug resistant tuberculosis in the capital of Lima.
Bangladesh, Ghana and Malawi
Developing and using mathematical modeling to better understand the transmission and distribution dynamics of the pathogen that causes rotavirus.
Working with colleagues to improve Neisseria meningitidis vaccine strategy. The pathogen causes meningococcal meningitis, a potentially severe illness that can result in disabilities or death.
Burkina Faso and Uganda
Working on translational research in the development of an antimalarial therapy and malaria epidemiology with colleagues in Africa; also studying ways to reduce the incidence of strokes.
Côte d’Ivoire and South Africa
With colleagues in Africa, researches the cost-effectiveness of alternative HIV prevention and patient care interventions to improve health outcomes.
Democratic Republic of the Congo
Predicting the treatment that is necessary for eradication of Yaws, a tropical infection of the skin, bones and joints caused by a spirochete bacterium, Treponema pallidum pertenue.
The Master of Hospital and Healthcare Administration Programs at Jimma University and Addis Ababa University are a collaborative effort between Yale School of Public Health and two of Ethiopia's leading universities.
Ethiopia, Ghana, Rwanda, South Africa and Uganda
Through the Health Extension Program, GHLI addresses primary care issues across Ethiopia that enable health care workers to bring public health to communities and improve maternal and child health outcomes.
Collaborating on interdisciplinary mathematical modeling approaches to better understand the dynamics of hookworm transmission among animals raised in rural and domestic settings.
India, Malawi, Nepal and Vietnam
Use of mathematical models to better understand epidemiological patterns in the incidence of typhoid fever, predict the potential impact of vaccination and identify key questions for future field and laboratory studies.
Kenya and Uganda
Sequenced the genome of a tsetse fly species that is responsible for transmitting Human African Trypanosomiasis, also known as African sleeping sickness. The finding may improve insecticides, traps and repellants.
Kenya and Uganda
Working with the Trypanosomiasis Research Center to strengthen the biomedical capacity of research scientists in Kenya and other countries in the region to fight the transmission of African sleeping sickness.
Applying interdisciplinary mathematical modeling approaches to address public health challenges for a wide range of infectious diseases, including HIV, TB, influenza, rabies and dengue.
Using spatial analysis to study the transmission dynamics of tuberculosis and also the rise of drug-resistant tuberculosis, a growing public health threat in many parts of the world.
Collaborating with colleagues in Arica and elsewhere to better understanding the prevalence of complex tuberculosis infections and well as its health effects.
Researching the biology and genomics of trypanosomes, the causative agent of African sleeping sickness. The disease continues to afflict people and livestock in the sub-Saharan region.
Using dynamic mathematical modeling approaches to evaluate the efficacy of treatment for human hookworm infection. The condition is pronounced in areas with poor sanitation.
Nine Southern African Countries
Modeling targeted tuberculosis interventions. It is estimated that there are millions of new TB cases each year and more than one million deaths are associated with the disease.
Building capacity for teaching and research in public health with the Bhutan Royal Institute of Health Sciences. This partnership has resulted in exchanges of scientists and students.
Public Health Training Program for Chinese officials at the China State Food and Drug Administration. The program provides guidance in the creation and implementation of future initiatives.
Public Health Training Program for Chinese officials at the China State Food and Drug Administration (sFDA). The program, which began in 2008, provides guidance in the creation and implementation of future directions and initiatives of the sFDA.
Studying the efficacy of the hepatitis B booster vaccine and the seroprevalence of surface antigens among young adults living in Qidong.
Creation of a joint biostatistics venture with Shanghai Jiao Tong University that will foster training and collaboration on cutting-edge biostatistical and translational medicine research.
Collaborative cancer epidemiology and pollution research projects, including a birth cohort study to understand early life environmental exposers and human health.
The Yale-Tsinghua Certificate Program in International Healthcare Management is working to strengthen the management and leadership skills of women in the health care sector.
GHLI - Bradley
Leading a case-control study of pancreatic cancer in Shanghai. The NIH-funded population-based case-control study seeks to better understands the origins of the disease.
Developing new approaches to measuring poverty and vulnerability, poverty and public investment and the impact of social networks on health among China’s rural and urban populations.
The Yale GHLI-Fudan University Mental Health Program teaches Chinese psychiatrists current best practices in psychiatric care and treatment, clinical research methodologies and leadership and management skills.
GHLI - Bradley
A multidisciplinary HIV and tuberculosis implementation sciences Fogarty Training Program to strengthen the capacity of the Chinese Center for Disease Control.
A randomized clinical trial of elective embryo cryopreservation followed by a programmed cycle of endometrial preparation and frozen embryo transfer compared to fresh embryo transfer in women with PCOS undergoing in vitro fertilization.
China, India, Russian Federation, and South Africa
Conducting HIV prevention research among various and vulnerable populations through the Fogarty AIDS International Training and Research Program.
China and Taiwan
Providing an updated and comprehensive description of health insurance coverage and utilization and their impacts on health and economic outcomes, with special attention to less-advantaged groups.
India, Nepal, Vietnam and Malawi
Use of mathematical models to better understand epidemiological patterns in the incidence of typhoid fever, predict the potential impact of vaccination and identify key questions for future studies.
Investigation of a causal connection between birth spacing and broad dimensions of child and maternal health status and dynamics using four waves of data from the Indonesia Family Life Survey.
Collaborating with colleagues at Tel Aviv University to study the cross-modal interactions in speeded classification of dynamic stimuli.
Working with pediatric infectious disease doctors to understand pneumococcal disease among both Jewish and Bedouin children living in southern Israel.
Israel and Europe
Participating in GLIOGENE, an international consortium of glioma researchers seeking to identify susceptibility genes in high-risk familial brain tumor pedigrees by screening glioma patients.
Japan and Germany
In collaboration with other researchers, studying the role of genes in encoding alcohol-metabolizing enzymes and the development of human colon cancer.
Two studies are underway that explore changing methods of responding to injection drug use in Hanoi and the impact that these responses have.