Multiple educational activities are available through the Yale and TFCARES programs on site in Tugela Ferry. For residents, J&J Scholars learn through a combination of hands-on clinical work and organized activities. Most generally work in the antiretroviral (ARV) clinic for the duration of their rotation. Residents work side-by-side with experienced clinicians who are immediately available to answer questions. A doctors meeting is held on Tuesday & Thursday mornings and consists of informal educational exchange in a morning report style conference, where clinical case discussion and/or didactics take place. All doctors attend, so it is the main venue for administrative matters as well. Each Scholar is expected to prepare and present one formal talk during the stay in Tugela Ferry.The primary role of the visiting J&J scholars is clinical care. The bulk of the six week rotation time is filled with patient care and education although it is possible to learn about the research activities to determine future interest in such activities. Educational materials and internet access are available for use and self motivated learning is encouraged.

Research Projects and Programs

tine test

Yale and TFCARES research studies focus on the integration of HIV and TB care and treatment and have demonstrated the benefit of this strategy, as well defining and creating and testing innovative strategies to confront the convergent epidemics of TB, HIV and drug resistant TB. (click to see publications).

We provided the initial description as well as the most comprehensive clinical and epidemiologic characterization of XDR TB to date, including studies of transmission in hospital and community settings and clinical outcomes. We have performed studies of new TB diagnostic tests and strategies among adults and children and developed new community based strategies to treat MDR TB and to identify HIV and drug susceptible and resistant TB earlier in the course of disease through intensive case finding (ICF).

In addition, we work collaboratively with basic and translational scientists at US and South African universities, to determine epidemiologic, mycobacterial and host immunologic factors impacting on disease transmission, incidence, prevalence, course and outcomes.

The research programs and staff are generally separate from staff providing clinical care and services. Students, and post graduate trainees and faculty interested in research activities are welcome and encouraged. Because of the nature of the research process, we expect a long duration of commitment to research projects.

Through rigorous on the ground and collaborative studies, we endeavor to provide new scientific and clinical knowledge and the evidence base for sound clinical and public health policies and practices directed against TB, HIV/AIDS and drug resistant TB. We have made numerous invited and submitted presentations at local, national and international meetings in the US, South Africa and other countries. We have published a large number of original research studies and reviews in the peer reviewed medical literature. The evidence provided by these collaborative efforts has resulted in improved health care programs that have been incorporated into provincial, national and international guidelines and health policies regarding HIV and drug susceptible and resistant TB.