Research and Global Health

The faculty and students in EMD carry out interdisciplinary research ranging from field and laboratory based studies in vector borne diseases, to emerging infections, to host defense and pathogenesis. Students have unique opportunities to use the Department's special laboratory facilities for bio-containment of infectious agents and for rearing and studying arthropod disease vectors. Faculty members also have extensive international collaborations underway in Africa, Asia, Central and South America, and Russia, which the students participate in.

Lymph Node

Autoimmunity & Lymphoid Organs

Dr. Ruddle’s laboratory focuses on understanding mechanisms of cell trafficking in inflammation and lymphoid organ development, particularly through high endothelial venules and lymphatic vessels.

Ixodes Scapularis Larva

Eco-epidemiology of Vector-borne and Zoonotic Diseases

The Department of Epidemiology of Microbial Diseases brings together expertise in entomology, eco-epidemiology and human pathology to study zoonotic diseases. Researchers are currently studying tick-borne pathogens that cause Lyme disease, babesia, and human ehrlichiosis; mosquito-borne pathogens causing West Nile...

Villagers

South Africa HIV/AIDS & TB

KwaZulu Natal province in South Africa has one of the highest rates of HIV infection in the world. Closely linked to this HIV epidemic is one of the world’s most severe TB epidemics. Yale first began work directed at the integration of TB and HIV treatment and care in KwaZuluNatal in 2000.

Malaria Ward

Genetics and Infectious Disease: Richard Bucala

Rick Bucala, MD, PhD, is Professor of Medicine, Pathology, and Epidemiology and Public Health. His research focuses on the role of immunity in the host-pathogen interaction and the clinical expression of different infectious diseases. 

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Global Health and Ethics

In addition to Dr. Khoshnood’s research in the U.S, China and Middle East which has focused on violence and HIV prevention, he is an influential leader in global health education at Yale.

HIV virus

HIV, TB, Hepatitis

HIV, viral hepatitis, TB, and other infectious diseases in the context of drug abuse and injection constitute a syndemic, i.e., the concentration of diseases or health conditions in which the interaction magnifies the negative health effects of the individual diseases or conditions.

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Infectious Disease Modeling

This research focuses on integrating epidemiology and evolutionary ecology or economics in order to generate predictions that could not be made by these disciplines alone. This interdisciplinary approach has widespread potential for answering evolutionary questions, explaining empirical observations and informing...

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Leishmaniasis

Leishmaniasis is caused by several species of flagellated protozoan parasites found particularly in Africa, Latin America, Asia, the Mediterranean basin and the Middle East. 

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Nutrition and Infectious Disease

Malnutrition affects over a billion people worldwide, ranging from the extremes of stunting and obesity, to the less visible micronutrient deficiencies, such as vitamin A, iron and zinc. 

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Sexually Transmitted Infections

Sexually transmitted infections are a major public health problem because of their high prevalence, associated poor health outcomes, and the disproportionate impact on vulnerable populations such as adolescents and minorities who are marginalized.

Sunil in Africa

Translational Research in Malaria

Professor Parikh's research interests focus on translational studies of malaria in sub-Saharan Africa. Dr. Parikh focuses upon several aspects of malaria: early host immune responses to infection, human genetics, and treatment.

Typhoid conditions

Transmission Dynamics of Enteric Diseases

Professor Pitzer’s research focuses on mathematical modeling of the transmission dynamics of enteric and imperfectly immunizing infections. She studies how interventions such as vaccination, improved treatment of cases, and improvements in sanitation affect disease transmission at the population level.

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Trypanosomiasis/Tsetse Research

The Aksoy lab studies multiple aspects of tsetse flies, the vectors of African trypanosomes. Trypanosomes are the causative agents of the devastating Sleeping Sickness disease in Sub-Saharan Africa. 

Brazil group

Urban Slum Health & Brazil

In collaboration with Brazilian Ministry of Health and the Oswaldo Cruz Foundation (Fiocruz) Yale researchers are actively engaged with community leaders and residents to implement field research and identify effective public health interventions for urban slum settlements.