Tissue Imaging Mass Spectrometry Symposium

Thursday, October 19, 2017

Cancer Cell

Winslow Auditorium, Room 109, LEPH, 60 College St, New Haven, CT 06510
10 AM - 5 PM

Tissue imaging mass spectrometry permits high-resolution spatial localization of metabolites, proteins and drugs within tissue sections in situ, allowing assessment of metabolic changes at the cellular level. When mass spectrometry images are overlaid onto conventional histology images it is possible to determine the molecules that correlate with tissue pathology, cell type, drug distribution and toxicity. This technique is particularly applicable to cancer research where molecules can be characterized with tumor cells and their microenvironment, allowing direct therapeutic effects to be assessed. Please join the Yale School of Public Health for this symposium, that will explore advances and challenges in tissue imaging mass spectrometry.

Agenda

10:00 AM: Vasilis Vasiliou, Professor & Chair, Dept. Environmental Health Sciences, Yale School of Public Health, Yale Cancer Center
Introduction

10:05 AM Keynote Speaker: Richard Caprioli, Professor of Biochemistry, Director of the Mass Spectrometry Research Center, Vanderbilt University School of Medicine
Imaging Mass Spectrometry: Molecular Microscopy for Biological/Clinical Research,  Abstract

10:50 AM Richard Goodwin, Principal Scientist - Mass Spectrometry Imaging, AstraZeneca
The Role of Mass Spectrometry Imaging in Oncology Drug Discovery

11:20 AM Stephen Castellino, Senior GSK Fellow and Head of US Ex Vivo Imaging, GlaxoSmithKline
Imaging MS: Visualizing Drug Disposition and Pharmacology in Tissue,  Abstract

11:50 AM Kirill A. Veselkov, Department of Surgery and Cancer, Imperial College London
Translational Data analytics for large-scale MSI data

12:20 - Lunch

1:20 Kevin L. Schey, Professor of Biochemistry and Ophthalmology & Visual Sciences, Deputy Director of Research, Imaging Mass Spectrometry Center, Vanderbilt University School of Medicine
Imaging Mass Spectrometry of Ocular Tissues: Molecular Signatures of Aging and Disease,  Abstract

1:50 PM Per E. Andrén, Professor of Mass Spectrometry Imaging, Director of National Resource for Mass Spectrometry Imaging, Dept. of Pharmaceutical Biosciences, Uppsala University, Uppsala, Sweden
Mapping the Brain Neurotransmitter Network with Mass Spectrometry Imaging Directly in Tissue Sections,  Abstract

2:20 PM Michael Angelo, Assistant Professor, Department of Pathology, Stanford University School of Medicine
High Dimensional IHC in Clinical Tissue Biopsies Using Multiplexed Ion Beam Imaging

2:50 PM Sheerin K. Shahidi-Latham, Head of Metabolomics & Imaging MS, Drug Metabolism & Pharmacokinetics Department, Genentech, Member of the Roche Group
High-Resolution Imaging MALDI Mass Spectrometry to Support Drug Discovery and Development

3:20 Q&A Session chaired by Mark Duncan and Caroline Johnson

4:00 PM - Wine and Cheese

Admission is free.

Sponsored by:

Waters logo.jpg  Yale Cancer Center 

Distilled Spirits Council Genentech