We are seeking a post-graduate associate with a Bachelor or Master degree or a postdoctoral associate with a Doctoral degree in biologically related sciences.
Our lab undertakes a reverse-genetic approach to dissect molecular functions of the HtrA gene family, as well as complement factors whose mutations and/or polymorphisms have been linked to human diseases, including Parkinson’s and macular degeneration, among others. In doing so we have generated several lines of Cre-Lox knockout and knock-in “humanized” mice. Successful candidates are expected to thoroughly study these mice.
The best-suited candidates should have strong communication skills and solid training in the use of a wide range of basic cellular and molecular biology techniques. Basic techniques may include PCR-based genotyping, mRNA isolation and quantification, in situ hybridization, western blot, and other forms of protein quantification, tissue embedding and sectioning, antibody-based staining of tissues, and microscopy techniques with various resolutions. Since our goal is to use a murine model to understand the mechanisms of human diseases, candidates having knowledge in both mouse and human genetics are preferred. A background in neuroscience or immunology with qualitative and quantitative analytical skills is highly desirable, although not necessary. In addition, candidates should have had training in handling live mice in line with IACUC guidelines.
Please submit a cover letter along with CV, and contact information for 3 professional references and apply online at:
For any additional information, please visit http://publichealth.yale.edu and contact:
Dr. Josephine Hoh
Associate Professor with Tenure
Department of Environmental Health Sciences
Yale School of Public Health
Yale University is an Affirmative Action/Equal Opportunity Employer and welcomes applications from women, members of minority groups, persons with disabilities and protected veterans.