Robert J Alpern, MD

Ensign Professor of Medicine (Nephrology); Dean, Yale School of Medicine

Research Interests

Acid-Base Equilibrium; Acidosis, Renal Tubular; Kidney; Nephrology; Renal Circulation; Urination; Membrane Transport Proteins; Physiological Processes; Renal Elimination

Research Organizations

Internal Medicine: Nephrology

Research Summary

Research on the regulation of kidney transport proteins has helped to define the mechanisms by which the kidney transports acid. Subsequently has focused on the mechanisms by which kidney cells sense excess acid and initiate a signaling cascade that alters the expression, cellular location, and function of many proteins in the cell, resulting in enhanced acid transport and urinary excretion.

Specialized Terms: Epithelial physiology; Membrane transport; Acid-base homeostasis

Extensive Research Description

Dr. Alpern’s research has focused on the regulation of kidney transport proteins.

Selected Publications

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