Yale Journal of Biology & Medicine

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This issue's focus topic is Translational Medicine. On the cover: Personal genomics aims to sequence a patient’s DNA to diagnose disease and identify effective treatment options. Image by Justin Fendos.

The Yale Journal of Biology and Medicine is a quarterly journal reviewed and edited by Yale biomedical faculty and students. The journal aims to showcase outstanding research articles from all areas of biology and medicine, to publish significant case reviews, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.


Editor's Picks from the Current Issue

Volume 85, Issue 1

Role of Microparticles in Dengue Virus Infection and its Impact on Medical Intervention Strategies

Kristina Bargeron Clark, Hui-Mien Hsiao, Sansanee Noisakran, Jih-Jin Tsai, and Guey Chuen Perng

Researchers have long sought to find classic dengue viral particles in human plasma but have had little success. This article discusses a potential alternate dengue viral morphology in patients and the implications for designing effective treatments.


Getting a Head Start: The Importance of Personal Genetics Education in High Schools

Johnny T. Kung and Marnie E. Gelbart

Kung and Gelbart highlight the growing necessity of educating students in genetics and discuss their efforts in developing the Personal Genetics Education Project at Harvard Medical School.


Guanfacine for the Treatment of Cognitive Disorders: A Century of Discoveries at Yale

Amy F.T. Arnsten and Lu E. Jin

Scientists at Yale have made significant progress understanding the cognitive roles of the prefrontal cortex and underlying neural circuits. Arnsten and Jin provide a historical review of these discoveries and how they have shaped therapies for cognitive disorders.


Mass Spectrometry-Based Proteomics for Translational Research: A Technical Overview

Joao A. Paulo, Vivek Kadiyala, Peter A. Banks, Hanno Steen, and Darwin L. Conwell

Paulo and colleagues present a comprehensive overview of using quantitative mass spectrometry-based proteomics for biomarker discovery in human disease.


Editorial: The Case Report in Context

Heather A. Carleton and Matthew L. Webb

Carleton and Webb review the key components of a well-written case report, in which the potential contributions to the medical literature of a timely and well-researched case report are illustrated by contemporary examples.