Yale Journal of Biology & Medicine

From initial discovery to final approval and marketing, drug development is a lengthly and strictly regulated process. The long and winding road of development is marked by distinct milestones; beginning with molecular testing and discovery, a promising drug is then tested in animal populations, before moving on to numerous phases of human clinical trials that begin with a small number of participants and gradually expand in scope as the efficacy, dosage, and potential side effects are calculated with increasing accuracy. The rate of failure is high, but drugs that are finally approved by regulatory bodies can offer hope to millions. Original cover design by Peter Harris.

The Yale Journal of Biology and Medicine is a PubMed-indexed, open access, quarterly journal edited by Yale medical, graduate, and professional students and peer reviewed by an extensive network of experts in the fields of biology and medicine. The journal aims to showcase outstanding research articles from all areas of biology and medicine, to publish significant case reviews, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.


To all interested authors: Starting in June 2015, YJBM began devoting entire issues to its focus topics. This means that all manuscripts in an issue will be related to the focus topic. As a result, we will not be considering off-topic manuscripts. Please keep an eye out for our future focus topics, and thank you for your understanding.

Upcoming focus topics:

June 2017: Infectious Diseases

September 2017: Comparative Medicine

December 2017: Gene Editing

March 2018: Sensory Biology and Pain

Editor's Picks from the Current Issue

Volume 90, Issue 1
Deputy editors: Corey Horien and Peijia Yuan

Variable Effects of Autophagy Induction by Trehalose on Herpesviruses Depending on Conditions of Infection

Jeffery L. Meier, Charles Grose


Alzheimer’s Toxic Amyloid Beta Oligomers: Unwelcome Visitors to the Na/K ATPase alpha3 Docking Station

Thomas DiChiara, Nadia DiNunno, Jeffrey Clark, Riana Lo Bu, Erika N. Cline, Madeline G. Rollins, Yuesong Gong, David L. Brody, Stephen G. Sligar, Pauline T. Velasco, Kirsten L. Viola, William L. Klein


Novel Molecular Strategies and Targets for Opioid Drug Discovery for the Treatment of Chronic Pain

Keith M. Olson, Wei Lei, Attila Keresztes, Justin LaVigne, John M. Streicher


Medication Safety in Clinical Trials: Role of the Pharmacist in Optimizing Practice, Collaboration, and Education to Reduce Errors

Jamie N. Brown, Sara R. Britnell, Andrew P. Stivers, Jennifer L. Cruz

YJBM Colloquium Series

Yale Journal of Biology & Medicine Presents:

“Through the FDA looking glass, and what can be found there”

Joseph S. Ross, MD, MHS Associate Professor of Medicine and Public Health, Yale School of Medicine

Tuesday March 7th, 2017
12:00 p.m. - 1:00 p.m.
BCMM 206/208, 295 Congress Ave, Second Floor, New Haven, CT

Download the PDF for more information