Yale Journal of Biology & Medicine

Epigenetic factors can determine the extent to which DNA is wrapped around histone proteins and the availability of genes in that particular DNA strand to be accessed. Tightly binding DNA around a compact group of histones renders that particular set of genes genes inactive. The less compact the histone grouping, the more genetic code is accessible. Different epigenetic factors or marks can distinguish the development of differing cell types, such as those in an eyeball versus an eyelash. Original cover design by Peter Harris.

The Yale Journal of Biology and Medicine is a PubMed-indexed, open access, quarterly journal edited by Yale medical, graduate, and professional students and peer reviewed by an extensive network of experts in the fields of biology and medicine. The journal aims to showcase outstanding research articles from all areas of biology and medicine, to publish significant case reviews, and to provide both perspectives on personal experiences in medicine and reviews of the current state of biology and medicine.


To all interested authors: Starting in June 2015, YJBM began devoting entire issues to its focus topics. This means that all manuscripts in an issue will be related to the focus topic. As a result, we will not be considering off-topic manuscripts. Please keep an eye out for our future focus topics, and thank you for your understanding.

Upcoming focus topics:

March 2017: Drug Development

June 2017: Infectious Diseases

September 2017: Comparative Medicine

December 2017: Gene Editing

March 2018: Sensory Biology and Pain

Editor's Picks from the Current Issue

Volume 89, Issue 4
Deputy editors: Carol Gianessi and Michael Lacy

CBX Chromodomain Inhibition Enhances Chemotherapy Response in Glioblastoma Multiforme

Katelyn E. Connelly, Emily C. Martin, Emily C. Dykhuizen


Editing the Neuronal Genome: a CRISPR View of Chromatin Regulation in Neuronal Development, Function, and Plasticity

Marty G. Yang and Anne E. West


What Drives Positive Selection in the Drosophila piRNA Machinery? The Genomic Autoimmunity Hypothesis

Justin P. Blumenstiel, Alexandra A. Erwin, and Lucas W. Hemmer


Emerging Functions of Circular RNAs

Mariela Cortés-López and Pedro Miura

YJBM Colloquium Series

Yale Journal of Biology & Medicine Presents:

“Through the FDA looking glass, and what can be found there”

Joseph S. Ross, MD, MHS Associate Professor of Medicine and Public Health, Yale School of Medicine

Tuesday March 7th, 2017
12:00 p.m. - 1:00 p.m.
BCMM 206/208, 295 Congress Ave, Second Floor, New Haven, CT

Download the PDF for more information