Current Dean's Workshops

Welcome to the Dean's Workshops website

The Dean's Workshops series brings together physicians and scientists from across the School of Medicine, the Yale medical center, and Yale University to address topics of critical importance in advancing biomedical research and patient care.

The workshops serve as a forum for new ideas and collaborations across disciplines.

Krios and Cryo-Electron Microscopy at Yale

Thursday, October 26, 2017, 1:00–5:00 p.m.
The Anlyan Center Auditorium, N143
300 Cedar St., New Haven

Three scientists were awarded the Nobel Prize in Chemistry this month for their development of this revolutionary new technology, that has helped further elucidate biological structures in atomic detail. Yale recently purchased a Titan Krios cryo-electron microscope, which greatly enhances our ability to examine the characteristics of biological specimens. This device also brings cryo-electron tomography (cryo-ET)—an advance that builds upon cryo-EM—to our campus. This workshop will describe the cryo-EM resources available to scientists at Yale, and highlight some of the exciting new scientific advances made by Yale investigators using cryo-EM and cryo-ET. 

Please feel free to attend any and all sessions as your schedule permits.

1:00 p.m.  Introduction
Michael C. Crair, PhD, Deputy Dean for Scientific Affairs (Basic Science Departments); William Ziegler III Professor; Departments of Neuroscience and Ophthalmology & Visual Science, Yale School of Medicine
1:10 p.m. Overview of Cryo-EM at Yale
Xinran Liu, MD, PhD, Research Scientist; Director of Electron Microscopy Core Facility, Yale School of Medicine Yong Xiong, PhD, Associate Professor; Department of Molecular Biophysics and Biochemistry; Director of Science Hill Cryo-EM Facility, Yale University
1:35 p.m. Introduction to Titan Krios
Shenping Wu, PhD, Research Scientist; Director of Titan Krios Core Facility, Yale University
2:20 p.m. Computational magic behind single-particle Cryo-EM
Fredrick J. Sigworth, PhD, Professor; Departments of Cellular and Molecular Physiology, Biomedical Engineering, and of Molecular Physics and Biochemistry, Yale School of Medicine
3:10 p.m. From X-Ray crystallography to Cryo-EM: Single-particle applications
Yong Xiong, PhD, Associate Professor; Department of Molecular Biophysics and Biochemistry, Yale University
4:00 p.m. The future of cryo-electron tomography: Cell biology at high resolution
Jun Liu, PhD, Associate Professor; Department of Microbial Pathogenesis, Microbial Sciences Institute, Yale School of Medicine