Laboratory Research

Our initial Pilot Project Program, The Ethel F. Donaghue Women's Health Investigator Program at Yale, has been made possible through the generous support of The Patrick and Catherine Weldon Donaghue Medical Research Foundation. Our pilot program is funded in part by the Maximilian E. & Marion O. Hoffman Foundation Inc. 

Click on the name of a study to see the findings

ADDICTIVE BEHAVIORS (SMOKING, ALCOHOL, DRUGS)

Jaakko Lappalainen, M.D., Ph.D.Assistant Professor of Psychiatry
Determining genetic factors that contribute to alcoholism in women
Marina R. Picciotto, Ph.D., Professor of Psychiatry, Pharmacology and Neurobiology
Studying the molecular basis for sex differences in depression and nicotine addiction

AUTOIMMUNE DISORDERS (LUPUS)

Mark Mamula, Ph.D., Professor of Internal Medicine (Rheumatology)
Understanding the causes of lupus
Mark Mamula, Ph.D., Professor of Internal Medicine (Rheumatology)
Collaborator: Bailin Liang, PhD
Finding the proteins that stimulate lupus

BONE HEALTH (OSTEOPOROSIS)

Angela Bruzzaniti, Ph.D.Associate Research Scientist in Orthopaedics & Rehabilitation
Finding the mechanisms in postmenopausal women that maintain bone

CANCER (BREAST, LUNG, AND OVARIAN)

Carlo Bifulco, M.D.Assistant Professor of Pathology
Using inflammation as a target for breast cancer therapies
Priscilla S. Dannies, Ph.D.Professor of Pharmacology
Improving chemotherapy for ovarian cancer
Michael P. DiGiovanna, M.D., Ph.D.Associate Professor of Medicine (Oncology) and Pharmacology
Targeting the mechanisms for treating lung cancer
Bruce Haffty, M.D.Professor, Department of Therapeutic Radiology
Developing a molecular analysis for early onset breast cancer
Barry M. Kacinski, M.D., Ph.D.Professor of Therapeutic Radiology
Sara Rockwell, Ph.D.Professor of Therapeutic Radiology and Pharmacology
Finding out whether alternative therapies affect breast cancer treatments
Alessandro Santin, M.D., Professor of Obstetrics, Gynecology and Reproductive Sciences
Developing the use of nanoparticles as a novel mechanism for advancing chemotherapy of ovarian cancer
Joann Sweasy, Ph.D., Professor of Therapeutic Radiology
Using human immune responses to create a new model for breast cancer therapies

ENDOCRINE

Julie Ann Sosa, M.D., Associate Professor of Surgery (Oncology)
Development of stem cells for therapy in hypoparathyroidism

GENETICS

Setsuko K. Chambers, M.D.Professor of Obstetrics and Gynecology
Developing gene therapy techniques for ovarian cancer
Stewart Frankel, Ph.D.Associate Research Scientist in Pediatrics and Developmental Biology
Understanding gender-specific regulation of genes
Harriet Kluger, M.D.Associate Professor of Internal Medicine (Oncology)
Identifying markers of invasive breast cancer

HORMONES & MENOPAUSE

Ronald S. Duman, Ph.D.Professor of Psychiatry and Pharmacology
Understanding the brain's response to ovarian hormones
Karyn Frick, Ph.D.Assistant Professor of Psychology
Determining the effects of hormone therapy on memory

INFECTIOUS DISEASE

Akiko Iwasaki, Ph.D., Professor of Immunobiology
Gender differences in infection and immunity to genital herpes

MOOD DISORDERS (DEPRESSION, BIPOLAR DISORDER)

Amy Arnsten, Ph.D.Professor of Neurobiology
Understanding the role of gender in stress-induced disorders
Ronald S. Duman, Ph.D.Professor of Psychiatry and Pharmacology
Deciphering the molecular determinants of post-partum mood disorders

REPRODUCTIVE HEALTH

Joshua Johnson, Ph.D., Assistant Professor of Obstetrics, Gynecology & Reproductive Sciences
Maintaining ovarian function and hormone production after cancer chemotherapy
Harvey Kliman, M.D., Ph.D.Research Scientist in Obstetrics and Gynecology
Understanding a critical step in human reproduction
Donna M. Neale, M.D.Assistant Professor of Obstetrics and Gynecology
Using specialized cells of the placenta as predictors of preeclampsia

TOURETTE'S & OCD

Paul Lombroso, M.D.Professor, Child Study Center
Determining sex differences in Tourette's syndrome and OCD