Clinical Trials Listing

What You Will Learn

  • How to pull information from the clinical trials system 
  • How to use this information to create an organized listing of clinical trials to your page

Quick Steps

  1. Create Clinical Trial Listing component; enter the correct Organization ID and Faculty Directory Link component.
  2. Insert Clinical Trial Listing component onto page as "Clinical Trial Listing" template 
  3. Create another page and insert Clinical Trial Listing component as "Clinical Trial" template
Rather than adding new clinical trials to your site adhoc, using the Clinical Trials component will pull in information from the Clinical Trials System, a function much like the News Listing and PubMed Feed.

I. Identify the Correct Organization in the Faculty Profile System

  1. Go to profile.yale.edu. Click on "Edit a Profile" and enter your log-in information.
  2. Click on Organizations at the top of the page. In the search field, enter the name of your parent and/or child organization. Once you've located the correct organization, click on the organization's page and look at the URL in the address bar of your browser. There will be a six digit organization ID number listed in the URL, record that ID for future use in Tridion. For example, I may be looking at the URL http://profile.yale.edu/organization/organization.asp?orgID=113722. The organization ID I want to record is 113722

II. Creating the Clinical Trials Listing Page in Tridion

Like Faculty Profile and News Listing pages, the Clinical Trials Listing requires you to build multiple components and pages. Follow these instructions closely. 

  1. In your Building Blocks folder, create a Clinical Trials folder. In this new folder, first create a new component and select the "Faculty Directory" schema. 
    • The only two fields that are important are "Name" and "Organization ID." Enter the Organization ID you previously recorded in the field.
    • Save & Close.
  2. In the same folder, create a new component and select "Link" from the schema menu.
    • Name: To help indicate that this is your link component, insert a title like "Clinical Trials Link."
    • Componentlink: Click on the yellow folder with the magnifying glass and select the Faculty Directory component you just created. 
    • Save & Close.
  3. With your Faculty Directory and Link components made, create another component and select the "Clinical Trial Listing" schema.
    • Name: Provide a name that clearly indicates what the component is, e.g. "Active Cancer Trials Listing"
    • Title: This is the title that will display above the Clinical Trial table.
    • Title Filter: Insert keywords to filter trials returned by the system based on words in the clinical trial's title.
    • Investigator Filter: Filters listings based on trial investigator's name.
    • Condition Filter: Filters based on the trial conditions, e.g., Cancer, Diabetes.
    • Category Filter: Filters based on trial categories. Please refer to the table below. 
    • OrgID Filter: Filters based on the Organization's ID from the Faculty Profile System and will return all trials tagged with that organization.
    • Show Child Organizations: Only used when an OrgID filter is used, if set to "yes" it would show all clinical trials belonging to the organization's first level child organizations.
    • Number of items to display in widget: If you opt to add a widget on your page using this very same component, this field specifies the number of trials to show in the widget.
    • trialDisplayLink: Click on the yellow folder with the magnifying glass. Select the Link component you created above.
    • Save & Close once finished. 
  4. With your components created, go into the Root Folder of your publication and create a Clinical Trials Structure Group. Insert a name and directory that would best suit your site's navigation.
  5. Now you will create the first of two new pages. Start with Listing page.
    • General Tab-
    • Name: 000_Clinical Trials
    • File Name: Index
    • Page Template and Metadata Schema: Leave as is.
    • Component Presentations Tab-
    • Insert the Clinical Trials Listing component you just created in step 3 and select "Clinical Trials Listing" from the Component Template menu. 
    • Save & Close.
  6. In the same Structure Group, you are going to create a "Details" page.
    • General Tab-
    • Name: Details (NO NUMBERS)
    • File Name: Trial
    • Page Template and Metadata Schema: Leave as is.
    • Component Presentations Tab-
    • Insert the Link component created in step 2 and select the "Clinical Trial" component template. 
    • Save & Close.
  7. Publish your Details page first, then your Listing page. 

Active Cancer Trials Example

10
19F-MRS (Magnetic Resonance Spectroscopy) Studies of in-vivo 5-Fluorouracil Pharmacokinetics with and without Bevacizumab in Patients with Liver Metastases from Adenocarcinoma of the colon
Disease/Condition: Colon Cancer
Principal Investigator: Howard S Hochster
A Couple-Based Relationship Strengthening HIV Intervention for Young Parents
Disease/Condition: HIV
Principal Investigator: Trace S Kershaw, PhD
A Double-Blind Study to Determine if Intraduodenal Indomethacin Can Decrease the Incidence of Post-ERCP Pancreatitis
Disease/Condition: Pancreatitis
Principal Investigator: Jamidar, Priya Arvind
A Multicenter, Open Label, Phase II Study of Bendamustine and Rituximab followed by 90-yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma (Fol-BRITe)
Disease/Condition: Follicular Lymphoma
Principal Investigator: Dennis L. Cooper
A Multi-Center, Phase 3, Double-Blind, Randomized, and Controlled Trial of KD019 vs Erlotinib in Subjects With Stage IIIB/IV Non-Small Cell Lung Cancer Who Have Progressed After First- or Second-Line Chemotherapy
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Daniel Morgensztern
A Multi-center, Placebo-controlled, randomized pilot study of the effect of Sorafenib on Portal Pressure in Patients with Cirrhosis, Significant Portal Hypertension and Hepatocellular Carcinoma Treated with Ablative Therapy and/or Transarterial Chemoembolization
Disease/Condition: Hepatocellular Carcinoma
Principal Investigator: Guadalupe Garcia-Tsao
A Multicenter, Randomized, Double-Blind, Phase 3 Study of Ramucirumab (IMC-1121B) Drug Product and Best Supportive Care (BSC) Versus Placebo as Second-Line Treatment in Patients With Hepatocellular Carcinoma Following First-Line Therapy With Sorafenib
Disease/Condition: Hepatocellular Carcinoma | Liver Cancer
Principal Investigator: Stacey M Stein
A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of Ascending Doses of AZD4547 in Patients with Advanced Solid Tumor Malignancies
Disease/Condition: Advanced Solid Cancers
Principal Investigator: Howard S Hochster
A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113
Disease/Condition: Advanced Malignancies | Anaplastic Large Cell Lymphoma | Carcinoma, Non-Small-Cell Lung | Diffuse Large Cell Lymphoma | Inflammatory Myofibroblastic Tumors
Principal Investigator: Scott Nicholas Gettinger
A Phase 2 Biomarker Study of Elotuzumab (Humanized anti-CS1 Monoclonal IgG1 Antibody) Monotherapy to Assess the Association Between NK Cell Status and Efficacy in High Risk Smoldering Myeloma
Disease/Condition: Smoldering Myeloma
Principal Investigator: Madhav V. Dhodapkar
A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD.
Disease/Condition: Coronary Artery Disease
Principal Investigator: Albert Sinusas, M.D.
A Phase 3 Open-label Safety Study of Cobicistat-containing Highly Active Antiretroviral Regimens in HIV-1 Infected Patients With Mild to Moderate Renal Impairment
Disease/Condition: HIV
Principal Investigator: Michael J Kozal
A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers
Disease/Condition: Recurrent Ovarian Cancer
Principal Investigator: Thomas Rutherford
A Phase 3, Randomized, Open Label Trial of Lenalidomide/Dexamethasone With or Without Elotuzumab in Subjects with Previously Untreated Multiple Myeloma (CA204006)
Disease/Condition: Multiple Myeloma
Principal Investigator: Dhodapkar, Madhav
A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL)
Disease/Condition: Advanced Stage Diffuse Large B-Cell Lymphoma
Principal Investigator: Daniel O. Persky
A Phase I/IIa, First Time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency
Disease/Condition: Breast Cancer (ER, PR, and HER2 negative) | Colorectal Cancer | Endometrial Cancer | Gastric Adenocarcinoma | Glioblastoma Multiforme | Head/ Neck Squamous Cell Carcinoma | Melanoma | Non-Small Cell Lung Cancer (NSCLC) | Ovarian Cancer | Prostate Cancer
Principal Investigator: Roy Herbst
A Phase II Study of Cixutumumab (IMC-A12; IND# 100947) in Combination with Temsirolimus (IND# 61010) in Pediatric Patients with Recurrent or Refractory Solid Tumors (ADVL1221)
Disease/Condition: Recurrent or Refractory Solid Tumors
Principal Investigator: Nina Kadan-Lottick
A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging
Disease/Condition: Hodgkin Lymphoma
Principal Investigator: Stuart Evan Seropian
A Phase III Randomized Trial of Chemotherapy with or without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer (ECOG E1305)
Disease/Condition: Head and Neck Cancer
Principal Investigator: Hari Anant Deshpande
A Phase III Study to Demonstrate the Antiviral Activity and Safety of Dolutegravir in HIV-1 Infected Adult Subjects With Treatment Failure on an Integrase Inhibitor Containing Regimen.
Disease/Condition: HIV
Principal Investigator: Michael J Kozal
A Pilot Pre-Operative Window Trial of Black Cohosh in Women with Ductal Carcinoma in situ
Disease/Condition: Breast Ductal Carcinoma In Situ (DCIS)
Principal Investigator: Erin Wysong Hofstatter
A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-cell Lymphoma Patients
Disease/Condition: Anaplastic Large Cell Lymphoma (ALCL) | Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) | Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral | other transformed T-cell lymphomas
Principal Investigator: Francine M Foss
A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin
Disease/Condition: Hepatorenal Syndrome Type 1
Principal Investigator: Sukru H Emre, MD, FACS
A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients using ColoPrint
Disease/Condition: Colon Cancer
Principal Investigator: Vikram Reddy
A Randomized Controlled Trial of Routine Shave Margins Versus Standard Partial Mastectomy in Breast Cancer Patients
Disease/Condition: Breast Cancer
Principal Investigator: Anees B. Chagpar
A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Erin Wysong Hofstatter
A RANDOMIZED, MULTICENTER, ADAPTIVE PHASE II/III STUDY TO EVALUATE THE EFFICACY AND SAFETY OF TRASTUZUMAB EMTANSINE (T-DM1) VERSUS TAXANE (DOCETAXEL OR PACLITAXEL) IN PATIENTS WITH PREVIOUSLY TREATED LOCALLY ADVANCED OR METASTATIC HER2-POSITIVE GASTRIC CANCER, INCLUDING ADENOCARCINOMA OF THE GASTROESOPHAGEAL JUNCTION
Disease/Condition: Adenocarcinoma of the Gastroesophageal Junction | Gastric Cancer
Principal Investigator: Howard S Hochster
A Randomized, Phase II, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating The Efficacy And Safety Of Onartuzumab (MetMAb) In Combination With 5-Fluorouracil, Folinic Acid, And Oxaliplatin (mFOLFOX6) In Patients With Metastatic HER2-Negative Gastroesophageal Cancer
Disease/Condition: Gastroesophageal Cancer
Principal Investigator: Jill Lacy
A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Roy Herbst
A Single-arm, Multicenter, Proof-of-Concept Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects with Elevated Serum Calcium Despite Recent Treatment with IV Bisphosphonates
Disease/Condition: Hypercalcemia
Principal Investigator: Karl L. Insogna
A Smoking Cessation Treatment for Adult Women
Disease/Condition: Nicotine Dependence
Principal Investigator: Andrea H. Weinberger, Ph.D.
A Study of CCCTC-binding Factor (CTCF) in Infantile Hemangiomas
Disease/Condition: Hemangioma
Principal Investigator: Deepak Narayan, MD
A Study to Examine the Human Gastrointestinal Tract Using the Confocal Endomicroscope
Disease/Condition: Digestive System Diseases
Principal Investigator: Michael Nathanson, MD, PhD
ACRIN 6690: A Prospective, Multicenter Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation
Disease/Condition: Liver Cancer
Principal Investigator: Jeffrey C. Weinreb
Alcohol Pharmacotherapy for HIV+ Prisoners
Disease/Condition: AIDS | Alcohol Dependence | Hazardous Drinking | Human Immunodeficiency Virus | Problem Drinking
Principal Investigator: Frederick L Altice, MD
Alzheimer's Disease Neuroimaging Initiative 2
Disease/Condition: Alzheimer's Disease | Mild Cognitive Impairment (MCI)
Principal Investigator: Christopher van Dyck, MD
Amyloid imaging in subjects with and at risk for Alzheimer’s disease:- a positron emission tomography (PET) study
Disease/Condition: Alzheimer's Disease
Principal Investigator: Christopher H Van Dyck
An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The “ACT IV” Study)
Disease/Condition: Glioblastoma
Principal Investigator: Kevin Patrick Becker
An Intervention to Improve Outcomes in Patients With Advanced Cancer
Disease/Condition: Cancer
Principal Investigator: Ruth McCorkle, RN, PhD
An Open Label Assessment of Safety and Efficacy of Ruxolitinib (INCB018424) in Subjects with Primary Myelofibrosis, Post Essential Thromboythemia Myelofibrosis and Post Polycythemia Vera Myelofibrosis Who Have Platelet Counts of 50x109 /L to 100 x 109/L
Disease/Condition: Post Essential Thromboythemia Myelofibrosis | Post Polycythemia Vera Myelofibrosis | Primary Myelofibrosis
Principal Investigator: Nikolai Alexandrovich Podoltsev
Anti-TNF Agents for the Treatment of Rheumatoid Arthritis
Disease/Condition: Rheumatoid Arthritis
Principal Investigator: Insoo Kang, MD
Assessment Tool for Older Patients With Cancer
Disease/Condition: Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Unspecified Adult Solid Tumor, Protocol Specific
Principal Investigator: Gross, Cary P
BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Roy Herbst
Biological Clock Dysfunction in Optic Nerve Hypoplasia
Disease/Condition: Biological Clock Dysfunction | Optic Nerve Hypoplasia
Principal Investigator: Rivkees, Scott A
Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma
Disease/Condition: Neuroblastoma
Principal Investigator: Kupfer, Gary
Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma
Disease/Condition: Leukemia | Lymphoma
Principal Investigator: Gary Kupfer
Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia
Disease/Condition: Cognitive/Functional Effects | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment
Principal Investigator: Gary Kupfer
Bronchial Thermoplasty in Severe Persistent Asthma
Disease/Condition: Severe Asthma
Principal Investigator: Geoffrey Chupp, MD
Calcitonin for Treating X-linked Hypophosphatemia
Disease/Condition: Hypophosphatemic Rickets, X Linked Dominant
Principal Investigator: Karl L Insogna, MD
Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia
Disease/Condition: Schizoaffective Disorder | Schizophrenia
Principal Investigator: Ranganathan, Mohini
Cannabinoid Modulation of Pain
Disease/Condition: Pain
Principal Investigator: Richard A Sewell, M.D.
Cannabinoid Receptor Function & Alcoholism
Disease/Condition: Alcoholism
Principal Investigator: D'Souza, Deepak C.
Cannabinoids, Neural Synchrony, and Information Processing
Disease/Condition: Cannabis | Psychotic Disorders
Principal Investigator: D'Souza, Deepak C.
Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer
Disease/Condition: Endometrial Cancer
Principal Investigator: Masoud Azodi
Cardiovascular Risk Assessment in Women with Early Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Jessica Marie Coviello
Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy
Disease/Condition: Fungal Infection | Leukemia | Neutropenia
Principal Investigator: Nina Kadan-Lottick
Cetuximab and Radiation Therapy in Head and Neck Cancer
Disease/Condition: Head and Neck Cancer
Principal Investigator: Roy Decker
Changing Lifestyles for Better Health
Disease/Condition: Type 2 Diabetes Mellitus
Principal Investigator: Tamborlane, William V
Characterization of Tumor Cells in the Arterial and Venous Circulations of Non Small Cell Lung Cancer Patients
Disease/Condition: Non Small Cell Lung Cancer
Principal Investigator: Daniel J. Boffa
Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer
Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer
Disease/Condition: Fallopian Tube Cancer | Ovarian Cancer | Primary Peritoneal Cavity Cancer
Principal Investigator: Thomas J. Rutherford
Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Lung Cancer That Was Removed By Surgery
Disease/Condition: Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer | Stage IIIA Non-small Cell Lung Cancer
Principal Investigator: Scott Nicholas Gettinger
Chronic Alcohol and Brain Stress Circuit Response
Disease/Condition: Alcoholism | Stress
Principal Investigator: Rajita Sinha, PhD
Chronic Pain and Opioid Dependence Assessment and Treatment
Disease/Condition: Chronic Pain | Opioid Dependency
Principal Investigator: Barry, Declan
Clinical Trial of Integrated Treatment for Pain and Opioid Dependence
Disease/Condition: Chronic Pain | Opiate Dependence
Principal Investigator: Schottenfeld, Richard S
Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III
Disease/Condition: Intraventricular Hemorrhage
Principal Investigator: David M Greer
Cognitive Effects of Atomoxetine in Humans: Genetic Moderators
Disease/Condition: Addiction
Principal Investigator: Mehmet Sofuoglu, M.D., Ph.D.
Cognitive Enhancement as a Target for Cocaine Pharmacotherapy
Disease/Condition: Addiction
Principal Investigator: Mehmet Sofuoglu, M.D., Ph.D.
Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment
Disease/Condition: Cognitive Impairment | Substance Abuse | Substance Dependence
Principal Investigator: Morris D Bell, Ph.D.
Cognitive Training to Enhance VA Work Program Outcomes
Disease/Condition: Bipolar Disorder | Depression | Mental Illness | PTSD | Schizophrenia
Principal Investigator: Morris D Bell, PhD
Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder
Disease/Condition: Asperger's Disorder | Autism | Autism Spectrum Disorder (ASD | Pervasive Developmental Disorder (PDD-NOS)
Principal Investigator: Denis Sukhodolsky, Ph.D.
Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma
Disease/Condition: Sarcoma
Principal Investigator: Gary Kupfer
Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma
Disease/Condition: Chordoma | Desmoid Tumor | Sarcoma
Principal Investigator: Gary Kupfer
Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma
Disease/Condition: Rhabdomyosarcoma
Principal Investigator: Gary Kupfer
Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma
Disease/Condition: Brain and Central Nervous System Tumors | Kidney Cancer | Sarcoma
Principal Investigator: Gary Kupfer
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer
Disease/Condition: Liver Cancer
Principal Investigator: Nina Kadan-Lottick
Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma
Disease/Condition: Contiguous Stage II Adult Lymphoblastic Lymphoma | Noncontiguous Stage II Adult Lymphoblastic Lymphoma | Stage II Adult T-cell Leukemia/Lymphoma | Stage II Childhood Lymphoblastic Lymphoma | Stage III Adult Lymphoblastic Lymphoma | Stage III Adult T-cell Leukemia/Lymphoma | Stage III Childhood Lymphoblastic Lymphoma | Stage IV Adult Lymphoblastic Lymphoma | Stage IV Adult T-cell Leukemia/Lymphoma | Stage IV Childhood Lymphoblastic Lymphoma | T-cell Adult Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia
Principal Investigator: Gary Kupfer
Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis
Disease/Condition: Cholangitis, Sclerosing
Principal Investigator: James L Boyer, MD
Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer
Compromised Microcirculation in Women With Polycystic Ovary Syndrome
Disease/Condition: Polycystic Ovary Syndrome
Principal Investigator: Stachenfeld, Nina S
Computer Based Training in Cognitive Behavioral Therapy Web-based
Disease/Condition: Substance Abuse
Principal Investigator: Kathleen Carroll, PhD
Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients
Disease/Condition: Hepatitis | HIV | Opioid Dependence
Principal Investigator: Kathleen M Carroll, PhD
Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma
Disease/Condition: Multiple Myeloma
Principal Investigator: Madhav Dhodapkar, M.D.
Defibrotide for Patients with Hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study (UNDER CFR 312.34)
Disease/Condition: Hepatic Veno-Occlusive Disease
Principal Investigator: Stuart Evan Seropian
Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study
Disease/Condition: Hepatic Veno-Occlusive Disease
Principal Investigator: Stuart Evan Seropian
Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion
Disease/Condition: Ischemic Heart Disease
Principal Investigator: Albert J Sinusas, MD
Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 2: Do Varenicline (Chantix) and Bupropion (Zyban) Change Alcohol Drinking?
Disease/Condition: Alcohol Drinking
Principal Investigator: McKee, Sherry
Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen
Disease/Condition: Hepatitis B Virus
Principal Investigator: Joseph K Lim
Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma
Disease/Condition: Malignant Melanoma
Principal Investigator: Mario Sznol
Duloxetine for the Treatment of Postpartum Depression
Disease/Condition: Major Depressive Disorder | Postpartum Depression
Principal Investigator: Yonkers, Kimberly Ann
Eculizumab Therapy for Chronic Complement-Mediated Injury in Kidney Transplantation
Disease/Condition: Kidney; Complications, Allograft
Principal Investigator: Sanjay Kulkarni, MD
Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes.
Disease/Condition: Hypo-unawareness | Type 1 Diabetes.
Principal Investigator: Robert Sherwin, MD
Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes.
Disease/Condition: Type 1 Diabetes
Principal Investigator: Robert Sherwin, MD
Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia
Disease/Condition: Hypoglycemia
Principal Investigator: Robert Sherwin, MD
Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders
Disease/Condition: Alcohol Reactivity
Principal Investigator: Sherry A McKee, PhD
Effectiveness and Cost Effectiveness of Peer Mentors in Reducing Hospital Use
Disease/Condition: Serious Mental Illness
Principal Investigator: Larry Davidson, PhD
Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women
Disease/Condition: HIV Infections | Pregnancy | Sexually Transmitted Diseases
Principal Investigator: Ickovics, Jeannette R
Effects of Delta-9-THC and Iomazenil in Healthy Humans
Disease/Condition: Mental Disorders | Psychotic Disorders | Schizophrenia
Principal Investigator: Deepak C D'Souza, M.D
Effects of Salvinorin A in Healthy Controls
Disease/Condition: Healthy
Principal Investigator: Ranganathan, Mohini
Efficacy and Tolerability of Riluzole in Treatment Resistant Depression
Disease/Condition: Depression
Principal Investigator: Gerard Sanacora, MD PhD
Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS)
Disease/Condition: Polycystic Ovarian Syndrome
Principal Investigator: Lubna Pal, MBBS MRCOG MSc
Enhancing a High School Based Smoking Cessation Program
Disease/Condition: Nicotine Dependence
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
Epidemiology and Genetics of Early Onset Basal Cell Carcinoma
Disease/Condition: Basal Cell Carcinoma
Principal Investigator: Susan T Mayne
Evaluation of Trastuzumab In Patients With HER2 Positive Persistent Or Recurrent Vulvar Paget's Disease
Disease/Condition: Paget's Disease of the Vulva
Principal Investigator: Thomas J. Rutherford, MD, PhD
Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse
Disease/Condition: Domestic Violence | Parenting | Substance Abuse
Principal Investigator: Carla S Stover, Ph.D.
FMRI of Stress and Addictive Disorders
Disease/Condition: Adolescents | Alcoholism | Cocaine Dependence | Opioid Dependence | Pathological Gamblers
Principal Investigator: Rajita Sinha, PhD
Fostering Mothers' Emotionally Responsive Parenting
Disease/Condition: Child Abuse | Maternal Substance Use
Principal Investigator: Suchman, Nancy E
GABA-glutamate Interactions and Psychosis
Disease/Condition: Cognitive Dysfunction
Principal Investigator: Gunduz-Bruce, Handan
Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse
Disease/Condition: Cocaine Dependence
Principal Investigator: Kathleen M Carroll, Ph.D.
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer
Disease/Condition: Distal Urethral Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Proximal Urethral Cancer | Recurrent Bladder Cancer | Recurrent Prostate Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Urethral Cancer | Stage IV Bladder Cancer | Stage IV Prostate Cancer | Transitional Cell Carcinoma of the Bladder | Urethral Cancer Associated With Invasive Bladder Cancer
Principal Investigator: Hari A. Deshpande
Genetics of Inflammatory Bowel Disease
Disease/Condition:  Ulcerative colitis | Crohn's disease | Inflammatory Bowel Disease
Principal Investigator: Judy H Cho
Guanfacine for Children with Tic Disorders
Disease/Condition: Chronic Motor Tic Disorder | Chronic Vocal Tic Disorder | Tourette Syndrome
Principal Investigator: Lawrence D Scahill
HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer
Disease/Condition: Advanced Breast Cancer
Principal Investigator: Abu-Khalaf, Maysa Mahmoud
Her2, c-kit EGFR and akt1 Expression in Carcinosarcomas of Female Genital Tract: Prognostic Factors or Potential Markers for Targeted Therapies
Disease/Condition: Gynecological Cancers
Principal Investigator: Ozlen Saglam
Hormones and Physical Exercise Study
Disease/Condition: Cancer
Principal Investigator: Melinda Liggett Irwin
Imaging the Effects of R-CHOP and other Anthracycline containing Chemotherapy on Cognitive Function in Patients with high-grade lymphoma
Disease/Condition: Lymphoma
Principal Investigator: Herta H Chao
Immune Function in T-Cell Lymphoma
Disease/Condition: Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral
Principal Investigator: Francine M Foss
Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation
Disease/Condition: Kidney Transplant
Principal Investigator: Richard Formica, Jr., MD
Immunology and Pathobiology of Plasma Cell Disorders
Disease/Condition: Plasma cell disorder
Principal Investigator: Madhav V. Dhodapkar
Impact of Exercise on Ovarian Cancer Prognosis
Disease/Condition: Ovarian Cancer
Principal Investigator: Melinda Liggett Irwin
Insulin Resistance Intervention After Stroke Trial
Disease/Condition: Diabetes | Myocardial Infarction | Stroke
Principal Investigator: Kernan, Walter Newberry
Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD)
Disease/Condition: Attention Deficit Hyperactivity Disorder (ADHD)
Principal Investigator: James Leckman, MD
Internet Treatment for Weight Loss in Primary Care
Disease/Condition: Obese | Overweight
Principal Investigator: Rachel Barnes, Ph.D.
Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers
Disease/Condition: Obesity | Overweight | Smoking Cessation
Principal Investigator: Marney A White, PhD, MS
Intravenous (IV) Nicotine Self Administration: Dose Ranging and Sex Differences in Smokers
Disease/Condition: Nicotine Addiction
Principal Investigator: Mehmet Sofuoglu, M.D,Ph.D.
Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism
Disease/Condition: Alcoholism
Principal Investigator: Ismene Leonida Petrakis
Intravenous Immunoglobulin for PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections)
Disease/Condition: Anxiety Disorder | Autoimmune Disease | Children | Obsessive-Complusive Disorder | PANDAS
Principal Investigator: James Frederick Leckman
Investigation Into Effects Upon Counterregulatory Responses to Hypoglycemia During Intensive Treatment of T1DM
Disease/Condition: Hypoglycemia | Type 1 Diabetes
Principal Investigator: Sherwin, Robert Stanley
Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma
Disease/Condition: Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma
Principal Investigator: Nina Kadan-Lottick
Kappa-PET Imaging and Naltrexone in Alcohol Drinking Behaviors
Disease/Condition: Alcohol Drinking
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
Ketamine for Depression and Alcohol Dependence
Disease/Condition: Alcohol Dependence | Depression
Principal Investigator: Ismene Leonida Petrakis
Ketamine/Placebo Family History Positive Study
Disease/Condition: Alcoholism
Principal Investigator: Petrakis, Ismene Leonida
Large Abdominal Hernia Repair With SurgiMend 3.0 (LAHRS 3.0)
Disease/Condition: Hernia
Principal Investigator: Kimberly A. Davis, M.D.
Longitudinal Assessment and Functional Outcomes in Patients with Hematologic Malignancies and Related Disorders
Disease/Condition: Hematologic Malignancies
Principal Investigator: Stephanie Halene
Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies
Disease/Condition: Brain and Central Nervous System Tumors | Chronic Myeloproliferative Disorders | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Lymphoma | Lymphoproliferative Disorder | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic Syndromes | Myelodysplastic/Myeloproliferative Neoplasms | Precancerous Condition | Unspecified Childhood Solid Tumor, Protocol Specific
Principal Investigator: Gary Kupfer
Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates
Disease/Condition: Parenteral Nutrition-Associated Cholestasis
Principal Investigator: Richard A Ehrenkranz, MD
Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Kupfer, Gary
Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma
Disease/Condition: Brain and Central Nervous System Tumors
Principal Investigator: Gary Kupfer
Maintenance Therapy with Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia
Disease/Condition: Chronic Lymphocytic Leukemia
Principal Investigator: Terri Lynn Parker
Mammosite Breast Brachytherapy Optimization in the Treatment of Breast Carcinoma
Disease/Condition: Breast Neoplasms
Principal Investigator: Weidhaas, Joanne Barnes
Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis
Disease/Condition: Cystic Fibrosis
Principal Investigator: Barbara I Kazmierczak, MD PhD
Minding the Baby Home Visiting: Program Evaluation
Disease/Condition: Attachment | Child Maltreatment | Infant Health | Maternal Sensitivity
Principal Investigator: Lois S Sadler, PhD
Modafinil, Sleep Architecture and Cocaine Relapse
Disease/Condition: Cocaine Dependence
Principal Investigator: Peter Morgan, MD, PhD
Modeling Stress-precipitated Smoking Behavior for Medication Development
Disease/Condition: Smoking
Principal Investigator: McKee, Sherry
N-acetylcysteine (NAC) for Children With Tourette Syndrome
Disease/Condition: Tic | Tourettes Syndrome
Principal Investigator: Michael H. Bloch, MD, MS
N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder
Disease/Condition: Obsessive-Compulsive Disorder
Principal Investigator: Michael H. Bloch, MD, MS
N-acetylcysteine in Intra-amniotic Infection/Inflammation
Disease/Condition: Chorioamnionitis | Infection | Inflammation | Labor, Premature | Preterm Premature Rupture of the Membranes
Principal Investigator: Buhimschi, Catalin Sorin
Naltrexone and Memantine Effects on Alcohol Drinking Behaviors
Disease/Condition: Alcohol Drinking
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
Natural History Study of the Development of Type 1 Diabetes
Disease/Condition: Diabetes Mellitus, Type 1
Principal Investigator: Herold, Kevan
Neural Correlates of Cognitive Rehabilitation in PTSD
Disease/Condition: Posttraumatic Stress Disorder | Traumatic Brain Injury
Principal Investigator: Brian Schweinsburg, Ph.D.
Neurofeedback of Activity in the Supplementary Motor Area for Tourette Syndrome
Disease/Condition: Chronic Tic Disorder | Tourette Syndrome
Principal Investigator: Michelle Hampson
Neuropsychological and Behavioral Testing in Young Patients With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET)
Disease/Condition: Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity | Cognitive/Functional Effects | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment | Radiation Toxicity | Therapy-related Toxicity
Principal Investigator: Gary Kupfer
Neurosurgery Patient Outcomes in Treating Spinal Disorders
Disease/Condition: Symptomatic Grade I Lumbar Spondylolisthesis | Symptomatic Lumbar Disc Herniation
Principal Investigator: Khalid M Abbed, MD
Ofatumumab vs. Rituximab Salvage Chemoimmunotherapy followed by ASCT in Relapsed or Refractory DLBCL (ORCHARDD Trial/ Phase III)
Disease/Condition: Diffuse Large B Cell Lymphoma
Principal Investigator: Stuart Evan Seropian
Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus
Disease/Condition: Diabetes Mellitus, Type 1
Principal Investigator: Herold, Kevan
Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed Persistent or Recurrent Uterine or Ovarian Cancer
Disease/Condition: Ovarian Cancer | Sarcoma
Principal Investigator: Dan-Arin Silasi
Parent-Adolescent Interactions and Adolescent Development
Disease/Condition: Substance Abuse
Principal Investigator: Tara Chaplin, Ph.D.
PET Imaging of the Kappa Opioid Receptor in Humans
Disease/Condition: Healthy Subjects
Principal Investigator: Yiyun Henry Huang
PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma
Disease/Condition: Limited-stage Diffuse Large B-Cell Lymphoma
Principal Investigator: Daniel O. Persky
Pharmacogenetics of Cannabinoid Response
Disease/Condition: COMT Gene Polymorphism
Principal Investigator: D'Souza, Deepak C.
Pharmacotherapy & CM for Opioid and Cocaine Dependence
Disease/Condition: Improve Memory | Impulse Control | Lower Cocaine Use | Treatment for Cocaine Addiction
Principal Investigator: James Poling, Ph.D.
Phase II Study of FOLFIRINOX for Advanced Pancreatic Cancer
Disease/Condition: Advanced Pancreatic Cancer | Metastatic Pancreatic Cancer | Pancreatic Cancer
Principal Investigator: Jill Lacy, MD
Phase III, Multi-Center, Randomized, Controlled Study to Assess the Efficacy and Safety of ON 01910.Na Administered in a 72-Hour Continuous IV Every Other Week in Myelodysplastic Syndrome Patients with Excess Blasts Relapsing After, or Refractory to, or Intolerant to Azacitidine or Decitabine.
Disease/Condition: Myelodysplastic Syndromes
Principal Investigator: Nikolai Alexandrovich Podoltsev
Pilot Study of a Raltegravir Based NRTI Sparing Regimen
Disease/Condition: Acquired Immune Deficiency Syndrome | AIDS | HIV Infections | Human Immunodeficiency Virus
Principal Investigator: Michael J Kozal, MD
Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients with Advanced Breast and Gastrointestinal Tumors
Disease/Condition: Gastrointestinal Tumors | Metastatic Breast Cancer
Principal Investigator: Gina G Chung
Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
Disease/Condition: Alcohol Dependence | Stress Disorders, Post-Traumatic
Principal Investigator: Petrakis, Ismene Leonida
Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse
Disease/Condition: Alcohol Dependence
Principal Investigator: Sinha, Rajita
Prevalence of Carbohydrate Intolerance in Lean and Obese Children
Disease/Condition: Acanthosis Nigricans | Diabetes | Glucose Intolerance | Obesity
Principal Investigator: Caprio, Sonia
Prevention of Type 2 Diabetes in Children With a Family-based Healthy Lifestyle Program
Disease/Condition: Impaired Glucose Tolerance
Principal Investigator: Robert S. Sherwin, MD
Prospective Multicenter Human Randomized Controlled Evaluation of NOTES® Cholecystectomy
Disease/Condition: Gall Bladder Diseases
Principal Investigator: Kurt Roberts, MD
Radiation Therapy in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Weidhaas, Joanne Barnes
Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer
Disease/Condition: Head and Neck Cancer
Principal Investigator: Daniel Morgensztern
Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer
Disease/Condition: Adenocarcinoma of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Stage IB Esophageal Cancer | Stage IIA Esophageal Cancer | Stage IIB Esophageal Cancer | Stage IIIA Esophageal Cancer | Stage IIIB Esophageal Cancer
Principal Investigator: Bryan William Chang
Randomized Double-Blind, Phase III Study of TAS-102 plus Best Supportive Care (BSC) Versus Placebo Plus Best Supportive Care in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapies
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Randomized, double-blind, Phase II Study of FOLFOX/Bevacizumab with MetMAb versus Placebo as First-Line Treatment for Patients with Metastatic Colorectal Cancer
Disease/Condition: Colorectal Cancer
Principal Investigator: Howard S Hochster
Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI)
Disease/Condition: Angina Pectoris | Coronary Artery Disease
Principal Investigator: Alexandra Lansky, MD
Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy
Disease/Condition: Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Neera K Dahl, MD, PhD
Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Gary Kupfer
Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia
Disease/Condition: Leukemia
Principal Investigator: Nina Kadan-Lottick
Safety and Pharmacokinetic Study of Oral Morphine Sulfate in Pediatric Subjects
Disease/Condition: Pain
Principal Investigator: Haleh Saadat, MD
Safety of Sports for Patients With Implantable Cardioverter-Defibrillators
Disease/Condition: Heart Arrhythmias
Principal Investigator: Lampert, Rachel J.
Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids
Disease/Condition: Pain
Principal Investigator: Haleh Saadat
Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With Ribavirin
Disease/Condition: Hepatitis C
Principal Investigator: Robert Douglas Bruce
Screening to Augment Referral to Treatment- Project START
Disease/Condition: Alcohol Abuse | Marijuana Abuse | Substance-Related Disorders | Tobacco Use Disorder
Principal Investigator: Kimberly A Yonkers, MD
Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD
Disease/Condition: Graft Versus Host Disease | Leukemia | Myelodysplastic Syndromes
Principal Investigator: Warren Shlomchik, MD
Sensitivity to Intravenous Nicotine: Genetic Moderators
Disease/Condition: Influence of OPRM1 A118G Status on Subjective Responses to IV Nicotine.
Principal Investigator: Mehmet Sofuoglu, M.D,Ph.D.
Sex Hormones and Orthostatic Tolerance
Disease/Condition: Orthostatic Intolerance
Principal Investigator: Nina Stachenfeld, PhD
Skeletal Muscle Metabolism in Young and Older Men & Women
Disease/Condition: Aging
Principal Investigator: Douglas E Befroy
Smoking Cessation Treatment for Head and Neck Cancer Patients
Disease/Condition: Smoking Cessation
Principal Investigator: Benjamin Toll, Ph.D.
Social Cognitive Training for Psychosis: Treatment Development
Disease/Condition: Psychosis | Schizophrenia
Principal Investigator: Joanna M Fiszdon
SOLX Gold Shunt for Refractory Glaucoma
Disease/Condition: Glaucoma | Glaucoma, Open Angle
Principal Investigator: James C Tsai, MD
Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer
Disease/Condition: Adult Primary Hepatocellular Carcinoma | Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer
Principal Investigator: Stacey M Stein
Specialized Treatment Early in Psychosis (STEP)
Disease/Condition: Schizophrenia and Disorders With Psychotic Features
Principal Investigator: Srihari, Vinod H.
Strategic Timing of Antiretroviral Treatment
Disease/Condition: HIV Infection
Principal Investigator: Gerald H Friedland, MD
Stress Management Among Latinos With Type 2 Diabetes
Disease/Condition: Diabetes Mellitus, Type 2
Principal Investigator: Rafael Pérez-Escamilla, Ph.D.
Stress Reactivity in Veterans Receiving Pharmacological Treatment for Post-traumatic Stress Disorder (PTSD) and Alcohol Dependence
Disease/Condition: Alcohol Dependence | Post-traumatic Stress Disorder
Principal Investigator: Elizabeth Ralevski, Ph.D.
Stress Reduction Program to Reduce Abnormal Heart Rhythms Treated With Implantable Cardioverter Defibrillators (The RISTA Study)
Disease/Condition: Arrhythmias, Cardiac
Principal Investigator: Matthew M. Burg
Study of Blood Samples From Newborns With Down Syndrome
Disease/Condition: Down Syndrome | Leukemia
Principal Investigator: Nina Kadan-Lottick
Study of Kidney Tumors in Young Patients
Disease/Condition: Kidney Cancer | Nonneoplastic Condition
Principal Investigator: Gary Kupfer
Study of Late-Occurring Complications in Childhood Cancer Survivors
Disease/Condition: Cancer
Principal Investigator: Kupfer, Gary
Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth
Disease/Condition: Beta-cell Function | Childhood Obesity | Impaired Glucose Tolerance | Metabolic Syndrome | Pre-diabetes
Principal Investigator: Caprio, Sonia
T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs
Disease/Condition: Type 1 Diabetes Mellitus
Principal Investigator: Kevan Herold
Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Erin Wysong Hofstatter
Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma
Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Previously Untreated Childhood Rhabdomyosarcoma | Stage IV Adult Soft Tissue Sarcoma
Principal Investigator: Nina Kadan-Lottick
Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk"
Disease/Condition: Autoantibody Positive | High Risk | Impaired Glucose Tolerance | Non-diabetic Relatives at Risk for Type 1 Diabetes
Principal Investigator: Kevan Herold, MD
Testing the Feasibility of a Nurse Patient Navigation Intervention in Lung Cancer
Disease/Condition: Lung Cancer
Principal Investigator: Ruth McCorkle
The CHIPS Trial (Control of Hypertension In Pregnancy Study)
Disease/Condition: Gestational Hypertension
Principal Investigator: Anna Katerina Sfakianaki
The Effects of ?-9-THC and Naloxone in Humans
Disease/Condition: Healthy
Principal Investigator: Deepak Cyril D''Souza
The Effects of Cannabidiol and ?-9-THC in Humans
Disease/Condition: Healthy
Principal Investigator: Mohini Ranganathan, M.D
The MagnaSafe Registry: Determining the Risks of Magnetic Resonance Imaging (MRI) in the Presence of Pacemakers and Implantable Cardioverter Defibrillators (ICDs)
Disease/Condition: Implantable Cardioverter Defibrillator Implanted | Need for MRI Imaging With Pacemaker or
Principal Investigator: Rachel Lampert, MD
The PhenoGenetic Project - Yale University
Disease/Condition: Healthy Subjects
Principal Investigator: Stephanie C Eisenbarth
The Role of Stress in Self-Control, Coping, and Emotion Regulation
Disease/Condition: Chronic Stress.
Principal Investigator: Rajita Sinha, PhD
The Testosterone Trial in Older Men
Disease/Condition: Andropause
Principal Investigator: Thomas Gill, M.D.
The Use of Propranolol to Block Memory Reconsolidation in PTSD
Disease/Condition: Posttraumatic Stress Disorders
Principal Investigator: Aikins, Deane
Tobacco Approach Avoidance Training for Adolescent Smokers-2
Disease/Condition: Tobacco Use Disorder
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
TODAY Genetics Study
Disease/Condition: Type 2 Diabetes
Principal Investigator: Sonia Caprio, MD
Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD)
Disease/Condition: Obsessive-Compulsive Disorder
Transitions: Linkages From Jail To Community
Disease/Condition: HIV | HIV Infections | Substance Abuse
Principal Investigator: Frederick Altice, MD
Treatment of Binge Eating in Obese Patients in Primary Care
Disease/Condition: Binge Eating | Obesity
Principal Investigator: Grilo, Carlos M
Treatment of Refractory Schizophrenia With Riluzole
Disease/Condition: Schizoaffective | Schizophrenia
Principal Investigator: Zimolo, Zoran
Treatment Study of Sleep Apnea Among Patients With Transient Ischemic Attack and Minor Stroke
Disease/Condition: Stroke | Transient Ischemic Attack
Principal Investigator: Christine Won
Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients
Disease/Condition: Alcoholism
Principal Investigator: Petrakis, Ismene Leonida
Understanding and Treating Disorders of Female Sexual Dysfunction
Disease/Condition: Female Sexual Dysfunction
Principal Investigator: Marsha Kathleen Guess
Varenicline on Reward Responses and Cognition in Adolescent Smokers
Disease/Condition: Tobacco Use Disorders
Principal Investigator: Suchitra Krishnan-Sarin, Ph.D.
Varenicline Treatment of Alcohol Dependence in Smokers
Disease/Condition: Alcohol Abuse | Alcohol Dependence | Smoking
Principal Investigator: Stephanie Samples O''Malley
Ventavis® Registry Protocol
Disease/Condition: Pulmonary Arterial Hypertension
Principal Investigator: Terence Keith Trow
Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor
Disease/Condition: Kidney Cancer
Principal Investigator: Kupfer, Gary
Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma
Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Mixed Childhood Rhabdomyosarcoma | Pleomorphic Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Childhood Rhabdomyosarcoma
Principal Investigator: Nina Kadan-Lottick
Web Based Renal Transplant Patient Medication Education
Disease/Condition: Renal Transplant Recipients
Web-based CBT4CBT for Alcohol
Disease/Condition: Alcohol Abuse or Dependence
Principal Investigator: Kathleen Carroll, PhD
Women With Cancer: An Exercise Study to Promote Health
Disease/Condition: Bone Loss | Cancer
Principal Investigator: M. Tish Knobf, PhD
Women's Experience with Triple Negative Breast Cancer
Disease/Condition: Breast Cancer
Principal Investigator: Yasemin Turkman
Yoga for Pain and Opioid Dependence
Disease/Condition: Chronic Pain | Opioid Addiction
Principal Investigator: Declan T Barry, Ph.D.
Zenith(R) Low Profile AAA Endovascular Graft Clinical Study
Disease/Condition: Abdominal Aortic Aneurysms | Aorto-iliac Aneurysms | Iliac Aneurysms
Principal Investigator: Muhs, Bart Edward
Ziprasidone in the Psychosis Prodrome
Disease/Condition: Psychosis Prodrome
Principal Investigator: Woods, Scott W