Clinical Trials Listing
What You Will Learn
- How to pull information from the clinical trials system
- How to use this information to create an organized listing of clinical trials to your page
Quick Steps
- Create Clinical Trial Listing component; enter the correct Organization ID and Faculty Directory Link component.
- Insert Clinical Trial Listing component onto page as "Clinical Trial Listing" template
- Create another page and insert Clinical Trial Listing component as "Clinical Trial" template
Rather than adding new clinical trials to your site adhoc, using the Clinical Trials component will pull in information from the Clinical Trials System, a function much like the News Listing and PubMed Feed.
I. Identify the Correct Organization in the Faculty Profile System
- Go to profile.yale.edu. Click on "Edit a Profile" and enter your log-in information.
- Click on Organizations at the top of the page. In the search field, enter the name of your parent and/or child organization. Once you've located the correct organization, click on the organization's page and look at the URL in the address bar of your browser. There will be a six digit organization ID number listed in the URL, record that ID for future use in Tridion. For example, I may be looking at the URL http://profile.yale.edu/organization/organization.asp?orgID=113722. The organization ID I want to record is 113722.
II. Creating the Clinical Trials Listing Page in Tridion
Like Faculty Profile and News Listing pages, the Clinical Trials Listing requires you to build multiple components and pages. Follow these instructions closely.
- In your Building Blocks folder, create a Clinical Trials folder. In this new folder, first create a new component and select the "Faculty Directory" schema.
- The only two fields that are important are "Name" and "Organization ID." Enter the Organization ID you previously recorded in the field.
- Save & Close.
- In the same folder, create a new component and select "Link" from the schema menu.
- Name: To help indicate that this is your link component, insert a title like "Clinical Trials Link."
- Componentlink: Click on the yellow folder with the magnifying glass and select the Faculty Directory component you just created.
- Save & Close.
- Name: To help indicate that this is your link component, insert a title like "Clinical Trials Link."
- With your Faculty Directory and Link components made, create another component and select the "Clinical Trial Listing" schema.
- Name: Provide a name that clearly indicates what the component is, e.g. "Active Cancer Trials Listing"
- Title: This is the title that will display above the Clinical Trial table.
- Title Filter: Insert keywords to filter trials returned by the system based on words in the clinical trial's title.
- Investigator Filter: Filters listings based on trial investigator's name.
- Condition Filter: Filters based on the trial conditions, e.g., Cancer, Diabetes.
- Category Filter: Filters based on trial categories. Please refer to the table below.
- OrgID Filter: Filters based on the Organization's ID from the Faculty Profile System and will return all trials tagged with that organization.
- Show Child Organizations: Only used when an OrgID filter is used, if set to "yes" it would show all clinical trials belonging to the organization's first level child organizations.
- Number of items to display in widget: If you opt to add a widget on your page using this very same component, this field specifies the number of trials to show in the widget.
- trialDisplayLink: Click on the yellow folder with the magnifying glass. Select the Link component you created above.
- Save & Close once finished.
- Name: Provide a name that clearly indicates what the component is, e.g. "Active Cancer Trials Listing"
- With your components created, go into the Root Folder of your publication and create a Clinical Trials Structure Group. Insert a name and directory that would best suit your site's navigation.
- Now you will create the first of two new pages. Start with Listing page.
- General Tab-
- Name: 000_Clinical Trials
- File Name: Index
- Page Template and Metadata Schema: Leave as is.
- Component Presentations Tab-
- Insert the Clinical Trials Listing component you just created in step 3 and select "Clinical Trials Listing" from the Component Template menu.
- Save & Close.
- In the same Structure Group, you are going to create a "Details" page.
- General Tab-
- Name: Details (NO NUMBERS)
- File Name: Trial
- Page Template and Metadata Schema: Leave as is.
- Component Presentations Tab-
- Insert the Link component created in step 2 and select the "Clinical Trial" component template.
- Save & Close.
- Publish your Details page first, then your Listing page.
Active Cancer Trials Example
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| 19F-MRS (Magnetic Resonance Spectroscopy) Studies of in-vivo 5-Fluorouracil Pharmacokinetics with and without Bevacizumab in Patients with Liver Metastases from Adenocarcinoma of the colon Disease/Condition: Colon Cancer Principal Investigator: Howard S Hochster |
| A Couple-Based Relationship Strengthening HIV Intervention for Young Parents Disease/Condition: HIV Principal Investigator: Trace S Kershaw, PhD |
| A Double-Blind Study to Determine if Intraduodenal Indomethacin Can Decrease the Incidence of Post-ERCP Pancreatitis Disease/Condition: Pancreatitis Principal Investigator: Jamidar, Priya Arvind |
| A Multicenter, Open Label, Phase II Study of Bendamustine and Rituximab followed by 90-yttrium (Y) Ibritumomab Tiuxetan for Untreated Follicular Lymphoma (Fol-BRITe) Disease/Condition: Follicular Lymphoma Principal Investigator: Dennis L. Cooper |
| A Multi-Center, Phase 3, Double-Blind, Randomized, and Controlled Trial of KD019 vs Erlotinib in Subjects With Stage IIIB/IV Non-Small Cell Lung Cancer Who Have Progressed After First- or Second-Line Chemotherapy Disease/Condition: Non Small Cell Lung Cancer Principal Investigator: Daniel Morgensztern |
| A Multi-center, Placebo-controlled, randomized pilot study of the effect of Sorafenib on Portal Pressure in Patients with Cirrhosis, Significant Portal Hypertension and Hepatocellular Carcinoma Treated with Ablative Therapy and/or Transarterial Chemoembolization Disease/Condition: Hepatocellular Carcinoma Principal Investigator: Guadalupe Garcia-Tsao |
| A Multicenter, Randomized, Double-Blind, Phase 3 Study of Ramucirumab (IMC-1121B) Drug Product and Best Supportive Care (BSC) Versus Placebo as Second-Line Treatment in Patients With Hepatocellular Carcinoma Following First-Line Therapy With Sorafenib Disease/Condition: Hepatocellular Carcinoma | Liver Cancer Principal Investigator: Stacey M Stein |
| A Phase 1, Open-Label, Multicentre Study to Assess the Safety, Tolerability, Pharmacokinetics and Preliminary Anti-tumor Activity of Ascending Doses of AZD4547 in Patients with Advanced Solid Tumor Malignancies Disease/Condition: Advanced Solid Cancers Principal Investigator: Howard S Hochster |
| A Phase 1/2 Study of the Oral ALK/EGFR Inhibitor AP26113 Disease/Condition: Advanced Malignancies | Anaplastic Large Cell Lymphoma | Carcinoma, Non-Small-Cell Lung | Diffuse Large Cell Lymphoma | Inflammatory Myofibroblastic Tumors Principal Investigator: Scott Nicholas Gettinger |
| A Phase 2 Biomarker Study of Elotuzumab (Humanized anti-CS1 Monoclonal IgG1 Antibody) Monotherapy to Assess the Association Between NK Cell Status and Efficacy in High Risk Smoldering Myeloma Disease/Condition: Smoldering Myeloma Principal Investigator: Madhav V. Dhodapkar |
| A Phase 3 Multi-center Study to Assess PET Imaging of Flurpiridaz F 18 Injection in Patients With CAD. Disease/Condition: Coronary Artery Disease Principal Investigator: Albert Sinusas, M.D. |
| A Phase 3 Open-label Safety Study of Cobicistat-containing Highly Active Antiretroviral Regimens in HIV-1 Infected Patients With Mild to Moderate Renal Impairment Disease/Condition: HIV Principal Investigator: Michael J Kozal |
| A Phase 3, Randomized, Double-Blind Trial of Weekly Paclitaxel Plus AMG 386 or Placebo in Women With Recurrent Partially Platinum Sensitive or Resistant Epithelial Ovarian, Primary Peritoneal or Fallopian Tube Cancers Disease/Condition: Recurrent Ovarian Cancer Principal Investigator: Thomas Rutherford |
| A Phase 3, Randomized, Open Label Trial of Lenalidomide/Dexamethasone With or Without Elotuzumab in Subjects with Previously Untreated Multiple Myeloma (CA204006) Disease/Condition: Multiple Myeloma Principal Investigator: Dhodapkar, Madhav |
| A Phase I/II Trial of Vorinostat (SAHA) (NSC-701852) in Combination with Rituximab-CHOP in Patients with Newly Diagnosed Advanced Stage Diffuse Large B-Cell Lymphoma (DLBCL) Disease/Condition: Advanced Stage Diffuse Large B-Cell Lymphoma Principal Investigator: Daniel O. Persky |
| A Phase I/IIa, First Time in human, open-label dose-escalation study of GSK2636771 in subjects with advanced solid tumors with PTEN deficiency Disease/Condition: Breast Cancer (ER, PR, and HER2 negative) | Colorectal Cancer | Endometrial Cancer | Gastric Adenocarcinoma | Glioblastoma Multiforme | Head/ Neck Squamous Cell Carcinoma | Melanoma | Non-Small Cell Lung Cancer (NSCLC) | Ovarian Cancer | Prostate Cancer Principal Investigator: Roy Herbst |
| A Phase II Study of Cixutumumab (IMC-A12; IND# 100947) in Combination with Temsirolimus (IND# 61010) in Pediatric Patients with Recurrent or Refractory Solid Tumors (ADVL1221) Disease/Condition: Recurrent or Refractory Solid Tumors Principal Investigator: Nina Kadan-Lottick |
| A Phase II Trial of Response-Adapted Therapy of Stage III-IV Hodgkin Lymphoma Using Early Interim FDG-PET Imaging Disease/Condition: Hodgkin Lymphoma Principal Investigator: Stuart Evan Seropian |
| A Phase III Randomized Trial of Chemotherapy with or without Bevacizumab in Patients with Recurrent or Metastatic Head and Neck Cancer (ECOG E1305) Disease/Condition: Head and Neck Cancer Principal Investigator: Hari Anant Deshpande |
| A Phase III Study to Demonstrate the Antiviral Activity and Safety of Dolutegravir in HIV-1 Infected Adult Subjects With Treatment Failure on an Integrase Inhibitor Containing Regimen. Disease/Condition: HIV Principal Investigator: Michael J Kozal |
| A Pilot Pre-Operative Window Trial of Black Cohosh in Women with Ductal Carcinoma in situ Disease/Condition: Breast Ductal Carcinoma In Situ (DCIS) Principal Investigator: Erin Wysong Hofstatter |
| A Pilot Study of Sorafenib Examining Biomarkers in Refractory or Relapsed T-cell Lymphoma Patients Disease/Condition: Anaplastic Large Cell Lymphoma (ALCL) | Angioimmunoblastic lymphadenopathy with dysproteinemia (AILD) | Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral | other transformed T-cell lymphomas Principal Investigator: Francine M Foss |
| A Placebo-Controlled, Double-Blind Study to Confirm the Reversal of Hepatorenal Syndrome Type 1 With Terlipressin Disease/Condition: Hepatorenal Syndrome Type 1 Principal Investigator: Sukru H Emre, MD, FACS |
| A Prospective Study for the Assessment of Recurrence Risk in Stage II Colon Cancer Patients using ColoPrint Disease/Condition: Colon Cancer Principal Investigator: Vikram Reddy |
| A Randomized Controlled Trial of Routine Shave Margins Versus Standard Partial Mastectomy in Breast Cancer Patients Disease/Condition: Breast Cancer Principal Investigator: Anees B. Chagpar |
| A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer Disease/Condition: Breast Cancer Principal Investigator: Erin Wysong Hofstatter |
| A RANDOMIZED, MULTICENTER, ADAPTIVE PHASE II/III STUDY TO EVALUATE THE EFFICACY AND SAFETY OF TRASTUZUMAB EMTANSINE (T-DM1) VERSUS TAXANE (DOCETAXEL OR PACLITAXEL) IN PATIENTS WITH PREVIOUSLY TREATED LOCALLY ADVANCED OR METASTATIC HER2-POSITIVE GASTRIC CANCER, INCLUDING ADENOCARCINOMA OF THE GASTROESOPHAGEAL JUNCTION Disease/Condition: Adenocarcinoma of the Gastroesophageal Junction | Gastric Cancer Principal Investigator: Howard S Hochster |
| A Randomized, Phase II, Multicenter, Double-Blind, Placebo-Controlled Study Evaluating The Efficacy And Safety Of Onartuzumab (MetMAb) In Combination With 5-Fluorouracil, Folinic Acid, And Oxaliplatin (mFOLFOX6) In Patients With Metastatic HER2-Negative Gastroesophageal Cancer Disease/Condition: Gastroesophageal Cancer Principal Investigator: Jill Lacy |
| A Randomized, Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC) Disease/Condition: Non Small Cell Lung Cancer Principal Investigator: Roy Herbst |
| A Single-arm, Multicenter, Proof-of-Concept Study of Denosumab in the Treatment of Hypercalcemia of Malignancy in Subjects with Elevated Serum Calcium Despite Recent Treatment with IV Bisphosphonates Disease/Condition: Hypercalcemia Principal Investigator: Karl L. Insogna |
| A Smoking Cessation Treatment for Adult Women Disease/Condition: Nicotine Dependence Principal Investigator: Andrea H. Weinberger, Ph.D. |
| A Study of CCCTC-binding Factor (CTCF) in Infantile Hemangiomas Disease/Condition: Hemangioma Principal Investigator: Deepak Narayan, MD |
| A Study to Examine the Human Gastrointestinal Tract Using the Confocal Endomicroscope Disease/Condition: Digestive System Diseases Principal Investigator: Michael Nathanson, MD, PhD |
| ACRIN 6690: A Prospective, Multicenter Comparison of Multiphase Contrast-Enhanced CT and Multiphase Contrast-Enhanced MRI for Diagnosis of Hepatocellular Carcinoma and Liver Transplant Allocation Disease/Condition: Liver Cancer Principal Investigator: Jeffrey C. Weinreb |
| Alcohol Pharmacotherapy for HIV+ Prisoners Disease/Condition: AIDS | Alcohol Dependence | Hazardous Drinking | Human Immunodeficiency Virus | Problem Drinking Principal Investigator: Frederick L Altice, MD |
| Alzheimer's Disease Neuroimaging Initiative 2 Disease/Condition: Alzheimer's Disease | Mild Cognitive Impairment (MCI) Principal Investigator: Christopher van Dyck, MD |
| Amyloid imaging in subjects with and at risk for Alzheimer’s disease:- a positron emission tomography (PET) study Disease/Condition: Alzheimer's Disease Principal Investigator: Christopher H Van Dyck |
| An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The “ACT IV” Study) Disease/Condition: Glioblastoma Principal Investigator: Kevin Patrick Becker |
| An Intervention to Improve Outcomes in Patients With Advanced Cancer Disease/Condition: Cancer Principal Investigator: Ruth McCorkle, RN, PhD |
| An Open Label Assessment of Safety and Efficacy of Ruxolitinib (INCB018424) in Subjects with Primary Myelofibrosis, Post Essential Thromboythemia Myelofibrosis and Post Polycythemia Vera Myelofibrosis Who Have Platelet Counts of 50x109 /L to 100 x 109/L Disease/Condition: Post Essential Thromboythemia Myelofibrosis | Post Polycythemia Vera Myelofibrosis | Primary Myelofibrosis Principal Investigator: Nikolai Alexandrovich Podoltsev |
| Anti-TNF Agents for the Treatment of Rheumatoid Arthritis Disease/Condition: Rheumatoid Arthritis Principal Investigator: Insoo Kang, MD |
| Assessment Tool for Older Patients With Cancer Disease/Condition: Cognitive/Functional Effects | Psychosocial Effects of Cancer and Its Treatment | Unspecified Adult Solid Tumor, Protocol Specific Principal Investigator: Gross, Cary P |
| BATTLE-2 Program: A Biomarker-Integrated Targeted Therapy Study in Previously Treated Patients With Advanced Non-Small Cell Lung Cancer Disease/Condition: Non Small Cell Lung Cancer Principal Investigator: Roy Herbst |
| Biological Clock Dysfunction in Optic Nerve Hypoplasia Disease/Condition: Biological Clock Dysfunction | Optic Nerve Hypoplasia Principal Investigator: Rivkees, Scott A |
| Biomarkers in Tumor Tissue Samples From Patients With Newly Diagnosed Neuroblastoma or Ganglioneuroblastoma Disease/Condition: Neuroblastoma Principal Investigator: Kupfer, Gary |
| Bortezomib and Combination Chemotherapy in Treating Young Patients With Relapsed Acute Lymphoblastic Leukemia or Lymphoblastic Lymphoma Disease/Condition: Leukemia | Lymphoma Principal Investigator: Gary Kupfer |
| Brain Function in Young Patients Receiving Methotrexate for Acute Lymphoblastic Leukemia Disease/Condition: Cognitive/Functional Effects | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment Principal Investigator: Gary Kupfer |
| Bronchial Thermoplasty in Severe Persistent Asthma Disease/Condition: Severe Asthma Principal Investigator: Geoffrey Chupp, MD |
| Calcitonin for Treating X-linked Hypophosphatemia Disease/Condition: Hypophosphatemic Rickets, X Linked Dominant Principal Investigator: Karl L Insogna, MD |
| Cannabidiol Treatment of Cognitive Dysfunction in Schizophrenia Disease/Condition: Schizoaffective Disorder | Schizophrenia Principal Investigator: Ranganathan, Mohini |
| Cannabinoid Modulation of Pain Disease/Condition: Pain Principal Investigator: Richard A Sewell, M.D. |
| Cannabinoid Receptor Function & Alcoholism Disease/Condition: Alcoholism Principal Investigator: D'Souza, Deepak C. |
| Cannabinoids, Neural Synchrony, and Information Processing Disease/Condition: Cannabis | Psychotic Disorders Principal Investigator: D'Souza, Deepak C. |
| Carboplatin and Paclitaxel With or Without Cisplatin and Radiation Therapy in Treating Patients With Stage I, Stage II, Stage III, or Stage IVA Endometrial Cancer Disease/Condition: Endometrial Cancer Principal Investigator: Masoud Azodi |
| Cardiovascular Risk Assessment in Women with Early Breast Cancer Disease/Condition: Breast Cancer Principal Investigator: Jessica Marie Coviello |
| Caspofungin Acetate or Fluconazole in Preventing Invasive Fungal Infections in Patients With Acute Myeloid Leukemia Who Are Undergoing Chemotherapy Disease/Condition: Fungal Infection | Leukemia | Neutropenia Principal Investigator: Nina Kadan-Lottick |
| Cetuximab and Radiation Therapy in Head and Neck Cancer Disease/Condition: Head and Neck Cancer Principal Investigator: Roy Decker |
| Changing Lifestyles for Better Health Disease/Condition: Type 2 Diabetes Mellitus Principal Investigator: Tamborlane, William V |
| Characterization of Tumor Cells in the Arterial and Venous Circulations of Non Small Cell Lung Cancer Patients Disease/Condition: Non Small Cell Lung Cancer Principal Investigator: Daniel J. Boffa |
| Chemotherapy and Radiation Therapy in Treating Young Patients With Newly Diagnosed, Previously Untreated, High-Risk Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Chemotherapy Toxicity On Quality of Life in Older Patients With Stage I, Stage II, Stage III, or Stage IV Ovarian Epithelial, Primary Peritoneal Cavity, or Fallopian Tube Cancer Disease/Condition: Fallopian Tube Cancer | Ovarian Cancer | Primary Peritoneal Cavity Cancer Principal Investigator: Thomas J. Rutherford |
| Chemotherapy With or Without Bevacizumab in Treating Patients With Stage IB, Stage II, or Stage IIIA Non-Small Lung Cancer That Was Removed By Surgery Disease/Condition: Stage IB Non-small Cell Lung Cancer | Stage IIA Non-small Cell Lung Cancer | Stage IIB Non-small Cell Lung Cancer | Stage IIIA Non-small Cell Lung Cancer Principal Investigator: Scott Nicholas Gettinger |
| Chronic Alcohol and Brain Stress Circuit Response Disease/Condition: Alcoholism | Stress Principal Investigator: Rajita Sinha, PhD |
| Chronic Pain and Opioid Dependence Assessment and Treatment Disease/Condition: Chronic Pain | Opioid Dependency Principal Investigator: Barry, Declan |
| Clinical Trial of Integrated Treatment for Pain and Opioid Dependence Disease/Condition: Chronic Pain | Opiate Dependence Principal Investigator: Schottenfeld, Richard S |
| Clot Lysis: Evaluating Accelerated Resolution of Intraventricular Hemorrhage Phase III Disease/Condition: Intraventricular Hemorrhage Principal Investigator: David M Greer |
| Cognitive Effects of Atomoxetine in Humans: Genetic Moderators Disease/Condition: Addiction Principal Investigator: Mehmet Sofuoglu, M.D., Ph.D. |
| Cognitive Enhancement as a Target for Cocaine Pharmacotherapy Disease/Condition: Addiction Principal Investigator: Mehmet Sofuoglu, M.D., Ph.D. |
| Cognitive Remediation and Work Therapy in the Initial Phase of Substance Abuse Treatment Disease/Condition: Cognitive Impairment | Substance Abuse | Substance Dependence Principal Investigator: Morris D Bell, Ph.D. |
| Cognitive Training to Enhance VA Work Program Outcomes Disease/Condition: Bipolar Disorder | Depression | Mental Illness | PTSD | Schizophrenia Principal Investigator: Morris D Bell, PhD |
| Cognitive-Behavioral Therapy for Irritability in Adolescents With High Functioning Autism Spectrum Disorder Disease/Condition: Asperger's Disorder | Autism | Autism Spectrum Disorder (ASD | Pervasive Developmental Disorder (PDD-NOS) Principal Investigator: Denis Sukhodolsky, Ph.D. |
| Collecting and Storing Samples of Blood and Tumor Tissue From Patients With Osteosarcoma Disease/Condition: Sarcoma Principal Investigator: Gary Kupfer |
| Collecting and Storing Tissue, Blood, and Bone Marrow Samples From Patients With Rhabdomyosarcoma or Other Soft Tissue Sarcoma Disease/Condition: Chordoma | Desmoid Tumor | Sarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy and Radiation Therapy in Treating Patients With Newly Diagnosed Rhabdomyosarcoma Disease/Condition: Rhabdomyosarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy in Treating Patients With Non-Metastatic Extracranial Ewing Sarcoma Disease/Condition: Brain and Central Nervous System Tumors | Kidney Cancer | Sarcoma Principal Investigator: Gary Kupfer |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed Liver Cancer Disease/Condition: Liver Cancer Principal Investigator: Nina Kadan-Lottick |
| Combination Chemotherapy in Treating Young Patients With Newly Diagnosed T-Cell Acute Lymphoblastic Leukemia or T-cell Lymphoblastic Lymphoma Disease/Condition: Contiguous Stage II Adult Lymphoblastic Lymphoma | Noncontiguous Stage II Adult Lymphoblastic Lymphoma | Stage II Adult T-cell Leukemia/Lymphoma | Stage II Childhood Lymphoblastic Lymphoma | Stage III Adult Lymphoblastic Lymphoma | Stage III Adult T-cell Leukemia/Lymphoma | Stage III Childhood Lymphoblastic Lymphoma | Stage IV Adult Lymphoblastic Lymphoma | Stage IV Adult T-cell Leukemia/Lymphoma | Stage IV Childhood Lymphoblastic Lymphoma | T-cell Adult Acute Lymphoblastic Leukemia | T-cell Childhood Acute Lymphoblastic Leukemia | Untreated Adult Acute Lymphoblastic Leukemia | Untreated Childhood Acute Lymphoblastic Leukemia Principal Investigator: Gary Kupfer |
| Combination Therapy With Ursodeoxycholic Acid (UDCA) and All-Trans Retinoic Acid (ATRA) for Treatment of Primary Sclerosing Cholangitis Disease/Condition: Cholangitis, Sclerosing Principal Investigator: James L Boyer, MD |
| Comparison of Radiation Therapy Regimens in Combination With Chemotherapy in Treating Young Patients With Newly Diagnosed Standard-Risk Medulloblastoma Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Compromised Microcirculation in Women With Polycystic Ovary Syndrome Disease/Condition: Polycystic Ovary Syndrome Principal Investigator: Stachenfeld, Nina S |
| Computer Based Training in Cognitive Behavioral Therapy Web-based Disease/Condition: Substance Abuse Principal Investigator: Kathleen Carroll, PhD |
| Computer-based Cognitive Behavioral Therapy for Risky Behaviors in Opioid Dependent Patients Disease/Condition: Hepatitis | HIV | Opioid Dependence Principal Investigator: Kathleen M Carroll, PhD |
| Continuous Versus Intermittent Dosing Regimens for Pomalidomide in Relapsed/Refractory Multiple Myeloma Disease/Condition: Multiple Myeloma Principal Investigator: Madhav Dhodapkar, M.D. |
| Defibrotide for Patients with Hepatic Veno-Occlusive Disease (VOD): A Treatment IND Study (UNDER CFR 312.34) Disease/Condition: Hepatic Veno-Occlusive Disease Principal Investigator: Stuart Evan Seropian |
| Defibrotide for Patients With Hepatic Veno-occlusive Disease: A Treatment IND Study Disease/Condition: Hepatic Veno-Occlusive Disease Principal Investigator: Stuart Evan Seropian |
| Detecting Heart Disease Using First Pass Imaging With Gated SPECT Perfusion Disease/Condition: Ischemic Heart Disease Principal Investigator: Albert J Sinusas, MD |
| Do Treatments for Smoking Cessation Affect Alcohol Drinking? Study 2: Do Varenicline (Chantix) and Bupropion (Zyban) Change Alcohol Drinking? Disease/Condition: Alcohol Drinking Principal Investigator: McKee, Sherry |
| Dose Ranging Study of Pegylated Interferon Lambda in Patients With Hepatitis B and Positive for the Hepatitis B e Antigen Disease/Condition: Hepatitis B Virus Principal Investigator: Joseph K Lim |
| Dose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant Melanoma Disease/Condition: Malignant Melanoma Principal Investigator: Mario Sznol |
| Duloxetine for the Treatment of Postpartum Depression Disease/Condition: Major Depressive Disorder | Postpartum Depression Principal Investigator: Yonkers, Kimberly Ann |
| Eculizumab Therapy for Chronic Complement-Mediated Injury in Kidney Transplantation Disease/Condition: Kidney; Complications, Allograft Principal Investigator: Sanjay Kulkarni, MD |
| Effect of a Medium Chain Triglyceride Supplemented Diet on Cognitive Function and Brain Activation in Type 1 Diabetes. Disease/Condition: Hypo-unawareness | Type 1 Diabetes. Principal Investigator: Robert Sherwin, MD |
| Effect of Formoterol on the Counterregulatory Hormonal Response to Hypoglycemia in Type 1 Diabetes. Disease/Condition: Type 1 Diabetes Principal Investigator: Robert Sherwin, MD |
| Effect of Naltrexone on Counterregulatory Mechanisms in Hypoglycemia Disease/Condition: Hypoglycemia Principal Investigator: Robert Sherwin, MD |
| Effect of Varenicline on Fixed-Dose Alcohol Administration in Participants With Alcohol Use Disorders Disease/Condition: Alcohol Reactivity Principal Investigator: Sherry A McKee, PhD |
| Effectiveness and Cost Effectiveness of Peer Mentors in Reducing Hospital Use Disease/Condition: Serious Mental Illness Principal Investigator: Larry Davidson, PhD |
| Effectiveness of Integrating Prenatal Care in Reducing HIV/STDs Among Young Pregnant Women Disease/Condition: HIV Infections | Pregnancy | Sexually Transmitted Diseases Principal Investigator: Ickovics, Jeannette R |
| Effects of Delta-9-THC and Iomazenil in Healthy Humans Disease/Condition: Mental Disorders | Psychotic Disorders | Schizophrenia Principal Investigator: Deepak C D'Souza, M.D |
| Effects of Salvinorin A in Healthy Controls Disease/Condition: Healthy Principal Investigator: Ranganathan, Mohini |
| Efficacy and Tolerability of Riluzole in Treatment Resistant Depression Disease/Condition: Depression Principal Investigator: Gerard Sanacora, MD PhD |
| Endometrial Effects of Metformin Action in Women With Polycystic Ovarian Syndrome (PCOS) Disease/Condition: Polycystic Ovarian Syndrome Principal Investigator: Lubna Pal, MBBS MRCOG MSc |
| Enhancing a High School Based Smoking Cessation Program Disease/Condition: Nicotine Dependence Principal Investigator: Suchitra Krishnan-Sarin, Ph.D. |
| Epidemiology and Genetics of Early Onset Basal Cell Carcinoma Disease/Condition: Basal Cell Carcinoma Principal Investigator: Susan T Mayne |
| Evaluation of Trastuzumab In Patients With HER2 Positive Persistent Or Recurrent Vulvar Paget's Disease Disease/Condition: Paget's Disease of the Vulva Principal Investigator: Thomas J. Rutherford, MD, PhD |
| Fathers for Change for Men With Co-occurring Domestic Violence and Substance Abuse Disease/Condition: Domestic Violence | Parenting | Substance Abuse Principal Investigator: Carla S Stover, Ph.D. |
| FMRI of Stress and Addictive Disorders Disease/Condition: Adolescents | Alcoholism | Cocaine Dependence | Opioid Dependence | Pathological Gamblers Principal Investigator: Rajita Sinha, PhD |
| Fostering Mothers' Emotionally Responsive Parenting Disease/Condition: Child Abuse | Maternal Substance Use Principal Investigator: Suchman, Nancy E |
| GABA-glutamate Interactions and Psychosis Disease/Condition: Cognitive Dysfunction Principal Investigator: Gunduz-Bruce, Handan |
| Galantamine to Enhance Cognitive Behavioral Therapy for Cocaine Abuse Disease/Condition: Cocaine Dependence Principal Investigator: Kathleen M Carroll, Ph.D. |
| Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer Disease/Condition: Distal Urethral Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Proximal Urethral Cancer | Recurrent Bladder Cancer | Recurrent Prostate Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Urethral Cancer | Stage IV Bladder Cancer | Stage IV Prostate Cancer | Transitional Cell Carcinoma of the Bladder | Urethral Cancer Associated With Invasive Bladder Cancer Principal Investigator: Hari A. Deshpande |
| Genetics of Inflammatory Bowel Disease Disease/Condition: Ulcerative colitis | Crohn's disease | Inflammatory Bowel Disease Principal Investigator: Judy H Cho |
| Guanfacine for Children with Tic Disorders Disease/Condition: Chronic Motor Tic Disorder | Chronic Vocal Tic Disorder | Tourette Syndrome Principal Investigator: Lawrence D Scahill |
| HDAC Inhibitor Vorinostat (SAHA) With Capecitabine (Xeloda) Using a New Weekly Dose Regimen for Advanced Breast Cancer Disease/Condition: Advanced Breast Cancer Principal Investigator: Abu-Khalaf, Maysa Mahmoud |
| Her2, c-kit EGFR and akt1 Expression in Carcinosarcomas of Female Genital Tract: Prognostic Factors or Potential Markers for Targeted Therapies Disease/Condition: Gynecological Cancers Principal Investigator: Ozlen Saglam |
| Hormones and Physical Exercise Study Disease/Condition: Cancer Principal Investigator: Melinda Liggett Irwin |
| Imaging the Effects of R-CHOP and other Anthracycline containing Chemotherapy on Cognitive Function in Patients with high-grade lymphoma Disease/Condition: Lymphoma Principal Investigator: Herta H Chao |
| Immune Function in T-Cell Lymphoma Disease/Condition: Lymphoma, T-Cell, Cutaneous | Lymphoma, T-Cell, Peripheral Principal Investigator: Francine M Foss |
| Immune Monitoring and CNI Withdrawal in Low Risk Recipients of Kidney Transplantation Disease/Condition: Kidney Transplant Principal Investigator: Richard Formica, Jr., MD |
| Immunology and Pathobiology of Plasma Cell Disorders Disease/Condition: Plasma cell disorder Principal Investigator: Madhav V. Dhodapkar |
| Impact of Exercise on Ovarian Cancer Prognosis Disease/Condition: Ovarian Cancer Principal Investigator: Melinda Liggett Irwin |
| Insulin Resistance Intervention After Stroke Trial Disease/Condition: Diabetes | Myocardial Infarction | Stroke Principal Investigator: Kernan, Walter Newberry |
| Integrated Brain, Body and Social Intervention for Attention Deficit Hyperactivity Disorder (ADHD) Disease/Condition: Attention Deficit Hyperactivity Disorder (ADHD) Principal Investigator: James Leckman, MD |
| Internet Treatment for Weight Loss in Primary Care Disease/Condition: Obese | Overweight Principal Investigator: Rachel Barnes, Ph.D. |
| Internet-Administered Smoking Cessation Treatment for Overweight and Obese Smokers Disease/Condition: Obesity | Overweight | Smoking Cessation Principal Investigator: Marney A White, PhD, MS |
| Intravenous (IV) Nicotine Self Administration: Dose Ranging and Sex Differences in Smokers Disease/Condition: Nicotine Addiction Principal Investigator: Mehmet Sofuoglu, M.D,Ph.D. |
| Intravenous Alcohol Administration Using BrAc Method in Healthy Subjects With and Without a Family History of Alcoholism Disease/Condition: Alcoholism Principal Investigator: Ismene Leonida Petrakis |
| Intravenous Immunoglobulin for PANDAS (Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections) Disease/Condition: Anxiety Disorder | Autoimmune Disease | Children | Obsessive-Complusive Disorder | PANDAS Principal Investigator: James Frederick Leckman |
| Investigation Into Effects Upon Counterregulatory Responses to Hypoglycemia During Intensive Treatment of T1DM Disease/Condition: Hypoglycemia | Type 1 Diabetes Principal Investigator: Sherwin, Robert Stanley |
| Irinotecan Hydrochloride and Cetuximab With or Without Ramucirumab in Treating Patients With Advanced Colorectal Cancer With Progressive Disease After Treatment With Bevacizumab-Containing Chemotherapy Disease/Condition: Colorectal Cancer Principal Investigator: Howard S Hochster |
| Isotretinoin With or Without Monoclonal Antibody, Interleukin-2, and Sargramostim Following Stem Cell Transplantation in Treating Patients With Neuroblastoma Disease/Condition: Disseminated Neuroblastoma | Localized Resectable Neuroblastoma | Localized Unresectable Neuroblastoma | Regional Neuroblastoma | Stage 4S Neuroblastoma Principal Investigator: Nina Kadan-Lottick |
| Kappa-PET Imaging and Naltrexone in Alcohol Drinking Behaviors Disease/Condition: Alcohol Drinking Principal Investigator: Suchitra Krishnan-Sarin, Ph.D. |
| Ketamine for Depression and Alcohol Dependence Disease/Condition: Alcohol Dependence | Depression Principal Investigator: Ismene Leonida Petrakis |
| Ketamine/Placebo Family History Positive Study Disease/Condition: Alcoholism Principal Investigator: Petrakis, Ismene Leonida |
| Large Abdominal Hernia Repair With SurgiMend 3.0 (LAHRS 3.0) Disease/Condition: Hernia Principal Investigator: Kimberly A. Davis, M.D. |
| Longitudinal Assessment and Functional Outcomes in Patients with Hematologic Malignancies and Related Disorders Disease/Condition: Hematologic Malignancies Principal Investigator: Stephanie Halene |
| Long-Term Follow-Up of Patients Who Have Participated in Children's Oncology Group Studies Disease/Condition: Brain and Central Nervous System Tumors | Chronic Myeloproliferative Disorders | Leukemia | Long-term Effects Secondary to Cancer Therapy in Children | Lymphoma | Lymphoproliferative Disorder | Multiple Myeloma and Plasma Cell Neoplasm | Myelodysplastic Syndromes | Myelodysplastic/Myeloproliferative Neoplasms | Precancerous Condition | Unspecified Childhood Solid Tumor, Protocol Specific Principal Investigator: Gary Kupfer |
| Low Dose Parenteral Fat for Prevention of Parenteral Nutrition Associated Cholestasis in Preterm Neonates Disease/Condition: Parenteral Nutrition-Associated Cholestasis Principal Investigator: Richard A Ehrenkranz, MD |
| Low-Dose or High-Dose Vincristine and Combination Chemotherapy in Treating Young Patients With Relapsed B-Cell Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Kupfer, Gary |
| Maintenance Chemotherapy or Observation Following Induction Chemotherapy and Radiation Therapy in Treating Younger Patients With Newly Diagnosed Ependymoma Disease/Condition: Brain and Central Nervous System Tumors Principal Investigator: Gary Kupfer |
| Maintenance Therapy with Lenalidomide Following Bendamustine and Rituximab Induction Therapy for Chronic Lymphocytic Leukemia Disease/Condition: Chronic Lymphocytic Leukemia Principal Investigator: Terri Lynn Parker |
| Mammosite Breast Brachytherapy Optimization in the Treatment of Breast Carcinoma Disease/Condition: Breast Neoplasms Principal Investigator: Weidhaas, Joanne Barnes |
| Microbiome Acquisition and Progression of Inflammation and Airway Disease in Infants and Children With Cystic Fibrosis Disease/Condition: Cystic Fibrosis Principal Investigator: Barbara I Kazmierczak, MD PhD |
| Minding the Baby Home Visiting: Program Evaluation Disease/Condition: Attachment | Child Maltreatment | Infant Health | Maternal Sensitivity Principal Investigator: Lois S Sadler, PhD |
| Modafinil, Sleep Architecture and Cocaine Relapse Disease/Condition: Cocaine Dependence Principal Investigator: Peter Morgan, MD, PhD |
| Modeling Stress-precipitated Smoking Behavior for Medication Development Disease/Condition: Smoking Principal Investigator: McKee, Sherry |
| N-acetylcysteine (NAC) for Children With Tourette Syndrome Disease/Condition: Tic | Tourettes Syndrome Principal Investigator: Michael H. Bloch, MD, MS |
| N-acetylcysteine (NAC) for Pediatric Obsessive-Compulsive Disorder Disease/Condition: Obsessive-Compulsive Disorder Principal Investigator: Michael H. Bloch, MD, MS |
| N-acetylcysteine in Intra-amniotic Infection/Inflammation Disease/Condition: Chorioamnionitis | Infection | Inflammation | Labor, Premature | Preterm Premature Rupture of the Membranes Principal Investigator: Buhimschi, Catalin Sorin |
| Naltrexone and Memantine Effects on Alcohol Drinking Behaviors Disease/Condition: Alcohol Drinking Principal Investigator: Suchitra Krishnan-Sarin, Ph.D. |
| Natural History Study of the Development of Type 1 Diabetes Disease/Condition: Diabetes Mellitus, Type 1 Principal Investigator: Herold, Kevan |
| Neural Correlates of Cognitive Rehabilitation in PTSD Disease/Condition: Posttraumatic Stress Disorder | Traumatic Brain Injury Principal Investigator: Brian Schweinsburg, Ph.D. |
| Neurofeedback of Activity in the Supplementary Motor Area for Tourette Syndrome Disease/Condition: Chronic Tic Disorder | Tourette Syndrome Principal Investigator: Michelle Hampson |
| Neuropsychological and Behavioral Testing in Young Patients With Medulloblastoma or Supratentorial Primitive Neuroectodermal Tumor (PNET) Disease/Condition: Brain and Central Nervous System Tumors | Chemotherapeutic Agent Toxicity | Cognitive/Functional Effects | Neurotoxicity | Psychosocial Effects of Cancer and Its Treatment | Radiation Toxicity | Therapy-related Toxicity Principal Investigator: Gary Kupfer |
| Neurosurgery Patient Outcomes in Treating Spinal Disorders Disease/Condition: Symptomatic Grade I Lumbar Spondylolisthesis | Symptomatic Lumbar Disc Herniation Principal Investigator: Khalid M Abbed, MD |
| Ofatumumab vs. Rituximab Salvage Chemoimmunotherapy followed by ASCT in Relapsed or Refractory DLBCL (ORCHARDD Trial/ Phase III) Disease/Condition: Diffuse Large B Cell Lymphoma Principal Investigator: Stuart Evan Seropian |
| Oral Insulin for Prevention of Diabetes in Relatives at Risk for Type 1 Diabetes Mellitus Disease/Condition: Diabetes Mellitus, Type 1 Principal Investigator: Herold, Kevan |
| Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery Disease/Condition: Colorectal Cancer Principal Investigator: Howard S Hochster |
| Paclitaxel and Carboplatin or Ifosfamide in Treating Patients With Newly Diagnosed Persistent or Recurrent Uterine or Ovarian Cancer Disease/Condition: Ovarian Cancer | Sarcoma Principal Investigator: Dan-Arin Silasi |
| Parent-Adolescent Interactions and Adolescent Development Disease/Condition: Substance Abuse Principal Investigator: Tara Chaplin, Ph.D. |
| PET Imaging of the Kappa Opioid Receptor in Humans Disease/Condition: Healthy Subjects Principal Investigator: Yiyun Henry Huang |
| PET-Directed Therapy in Treating Patients With Limited-Stage Diffuse Large B-Cell Lymphoma Disease/Condition: Limited-stage Diffuse Large B-Cell Lymphoma Principal Investigator: Daniel O. Persky |
| Pharmacogenetics of Cannabinoid Response Disease/Condition: COMT Gene Polymorphism Principal Investigator: D'Souza, Deepak C. |
| Pharmacotherapy & CM for Opioid and Cocaine Dependence Disease/Condition: Improve Memory | Impulse Control | Lower Cocaine Use | Treatment for Cocaine Addiction Principal Investigator: James Poling, Ph.D. |
| Phase II Study of FOLFIRINOX for Advanced Pancreatic Cancer Disease/Condition: Advanced Pancreatic Cancer | Metastatic Pancreatic Cancer | Pancreatic Cancer Principal Investigator: Jill Lacy, MD |
| Phase III, Multi-Center, Randomized, Controlled Study to Assess the Efficacy and Safety of ON 01910.Na Administered in a 72-Hour Continuous IV Every Other Week in Myelodysplastic Syndrome Patients with Excess Blasts Relapsing After, or Refractory to, or Intolerant to Azacitidine or Decitabine. Disease/Condition: Myelodysplastic Syndromes Principal Investigator: Nikolai Alexandrovich Podoltsev |
| Pilot Study of a Raltegravir Based NRTI Sparing Regimen Disease/Condition: Acquired Immune Deficiency Syndrome | AIDS | HIV Infections | Human Immunodeficiency Virus Principal Investigator: Michael J Kozal, MD |
| Pilot Study of Sorafenib and Bi-weekly Capecitabine in Patients with Advanced Breast and Gastrointestinal Tumors Disease/Condition: Gastrointestinal Tumors | Metastatic Breast Cancer Principal Investigator: Gina G Chung |
| Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD). Disease/Condition: Alcohol Dependence | Stress Disorders, Post-Traumatic Principal Investigator: Petrakis, Ismene Leonida |
| Prazosin to Reduce Stress-Induced Alcohol/Drug Craving and Relapse Disease/Condition: Alcohol Dependence Principal Investigator: Sinha, Rajita |
| Prevalence of Carbohydrate Intolerance in Lean and Obese Children Disease/Condition: Acanthosis Nigricans | Diabetes | Glucose Intolerance | Obesity Principal Investigator: Caprio, Sonia |
| Prevention of Type 2 Diabetes in Children With a Family-based Healthy Lifestyle Program Disease/Condition: Impaired Glucose Tolerance Principal Investigator: Robert S. Sherwin, MD |
| Prospective Multicenter Human Randomized Controlled Evaluation of NOTES® Cholecystectomy Disease/Condition: Gall Bladder Diseases Principal Investigator: Kurt Roberts, MD |
| Radiation Therapy in Treating Women Who Have Undergone Surgery For Ductal Carcinoma In Situ or Stage I or Stage II Breast Cancer Disease/Condition: Breast Cancer Principal Investigator: Weidhaas, Joanne Barnes |
| Radiation Therapy With or Without Cetuximab in Treating Patients Who Have Undergone Surgery for Locally Advanced Head and Neck Cancer Disease/Condition: Head and Neck Cancer Principal Investigator: Daniel Morgensztern |
| Radiation Therapy, Paclitaxel, and Carboplatin With or Without Trastuzumab in Treating Patients With Esophageal Cancer Disease/Condition: Adenocarcinoma of the Esophagus | Adenocarcinoma of the Gastroesophageal Junction | Stage IB Esophageal Cancer | Stage IIA Esophageal Cancer | Stage IIB Esophageal Cancer | Stage IIIA Esophageal Cancer | Stage IIIB Esophageal Cancer Principal Investigator: Bryan William Chang |
| Randomized Double-Blind, Phase III Study of TAS-102 plus Best Supportive Care (BSC) Versus Placebo Plus Best Supportive Care in Patients with Metastatic Colorectal Cancer Refractory to Standard Chemotherapies Disease/Condition: Colorectal Cancer Principal Investigator: Howard S Hochster |
| Randomized, double-blind, Phase II Study of FOLFOX/Bevacizumab with MetMAb versus Placebo as First-Line Treatment for Patients with Metastatic Colorectal Cancer Disease/Condition: Colorectal Cancer Principal Investigator: Howard S Hochster |
| Ranolazine for Incomplete Vessel Revascularization Post-Percutaneous Coronary Intervention (PCI) Disease/Condition: Angina Pectoris | Coronary Artery Disease Principal Investigator: Alexandra Lansky, MD |
| Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy Disease/Condition: Autosomal Dominant Polycystic Kidney Disease Principal Investigator: Neera K Dahl, MD, PhD |
| Risk-Adapted Chemotherapy in Younger Patients With Newly Diagnosed Standard-Risk Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Gary Kupfer |
| Risk-Based Classification System of Patients With Newly Diagnosed Acute Lymphoblastic Leukemia Disease/Condition: Leukemia Principal Investigator: Nina Kadan-Lottick |
| Safety and Pharmacokinetic Study of Oral Morphine Sulfate in Pediatric Subjects Disease/Condition: Pain Principal Investigator: Haleh Saadat, MD |
| Safety of Sports for Patients With Implantable Cardioverter-Defibrillators Disease/Condition: Heart Arrhythmias Principal Investigator: Lampert, Rachel J. |
| Safety of Twice Daily Oxycodone Hydrochloride Controlled-release Tablets in Children With Moderate to Severe Malignant and/ or Nonmalignant Pain Requiring Opioids Disease/Condition: Pain Principal Investigator: Haleh Saadat |
| Safety Study of Pegylated Interferon Lambda Plus Single or 2 Direct Antiviral Agents With Ribavirin Disease/Condition: Hepatitis C Principal Investigator: Robert Douglas Bruce |
| Screening to Augment Referral to Treatment- Project START Disease/Condition: Alcohol Abuse | Marijuana Abuse | Substance-Related Disorders | Tobacco Use Disorder Principal Investigator: Kimberly A Yonkers, MD |
| Selective Depletion of CD45RA+T Cells From Allogeneic Peripheral Blood Stem Cell Grafts for the Prevention of GVHD Disease/Condition: Graft Versus Host Disease | Leukemia | Myelodysplastic Syndromes Principal Investigator: Warren Shlomchik, MD |
| Sensitivity to Intravenous Nicotine: Genetic Moderators Disease/Condition: Influence of OPRM1 A118G Status on Subjective Responses to IV Nicotine. Principal Investigator: Mehmet Sofuoglu, M.D,Ph.D. |
| Sex Hormones and Orthostatic Tolerance Disease/Condition: Orthostatic Intolerance Principal Investigator: Nina Stachenfeld, PhD |
| Skeletal Muscle Metabolism in Young and Older Men & Women Disease/Condition: Aging Principal Investigator: Douglas E Befroy |
| Smoking Cessation Treatment for Head and Neck Cancer Patients Disease/Condition: Smoking Cessation Principal Investigator: Benjamin Toll, Ph.D. |
| Social Cognitive Training for Psychosis: Treatment Development Disease/Condition: Psychosis | Schizophrenia Principal Investigator: Joanna M Fiszdon |
| SOLX Gold Shunt for Refractory Glaucoma Disease/Condition: Glaucoma | Glaucoma, Open Angle Principal Investigator: James C Tsai, MD |
| Sorafenib Tosylate With or Without Doxorubicin Hydrochloride in Treating Patients With Locally Advanced or Metastatic Liver Cancer Disease/Condition: Adult Primary Hepatocellular Carcinoma | Advanced Adult Primary Liver Cancer | Localized Unresectable Adult Primary Liver Cancer | Recurrent Adult Primary Liver Cancer Principal Investigator: Stacey M Stein |
| Specialized Treatment Early in Psychosis (STEP) Disease/Condition: Schizophrenia and Disorders With Psychotic Features Principal Investigator: Srihari, Vinod H. |
| Strategic Timing of Antiretroviral Treatment Disease/Condition: HIV Infection Principal Investigator: Gerald H Friedland, MD |
| Stress Management Among Latinos With Type 2 Diabetes Disease/Condition: Diabetes Mellitus, Type 2 Principal Investigator: Rafael Pérez-Escamilla, Ph.D. |
| Stress Reactivity in Veterans Receiving Pharmacological Treatment for Post-traumatic Stress Disorder (PTSD) and Alcohol Dependence Disease/Condition: Alcohol Dependence | Post-traumatic Stress Disorder Principal Investigator: Elizabeth Ralevski, Ph.D. |
| Stress Reduction Program to Reduce Abnormal Heart Rhythms Treated With Implantable Cardioverter Defibrillators (The RISTA Study) Disease/Condition: Arrhythmias, Cardiac Principal Investigator: Matthew M. Burg |
| Study of Blood Samples From Newborns With Down Syndrome Disease/Condition: Down Syndrome | Leukemia Principal Investigator: Nina Kadan-Lottick |
| Study of Kidney Tumors in Young Patients Disease/Condition: Kidney Cancer | Nonneoplastic Condition Principal Investigator: Gary Kupfer |
| Study of Late-Occurring Complications in Childhood Cancer Survivors Disease/Condition: Cancer Principal Investigator: Kupfer, Gary |
| Study to Investigate the Pathophysiology of Type 2 Diabetes in Youth Disease/Condition: Beta-cell Function | Childhood Obesity | Impaired Glucose Tolerance | Metabolic Syndrome | Pre-diabetes Principal Investigator: Caprio, Sonia |
| T1DM Immunotherapy Using CD4+CD127lo/-CD25+ Polyclonal Tregs Disease/Condition: Type 1 Diabetes Mellitus Principal Investigator: Kevan Herold |
| Tamoxifen Citrate in Treating Patients With Metastatic or Recurrent Breast Cancer Disease/Condition: Breast Cancer Principal Investigator: Erin Wysong Hofstatter |
| Temozolomide, Cixutumumab, and Combination Chemotherapy in Treating Patients With Metastatic Rhabdomyosarcoma Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Embryonal Childhood Rhabdomyosarcoma | Metastatic Childhood Soft Tissue Sarcoma | Previously Untreated Childhood Rhabdomyosarcoma | Stage IV Adult Soft Tissue Sarcoma Principal Investigator: Nina Kadan-Lottick |
| Teplizumab for Prevention of Type 1 Diabetes In Relatives "At-Risk" Disease/Condition: Autoantibody Positive | High Risk | Impaired Glucose Tolerance | Non-diabetic Relatives at Risk for Type 1 Diabetes Principal Investigator: Kevan Herold, MD |
| Testing the Feasibility of a Nurse Patient Navigation Intervention in Lung Cancer Disease/Condition: Lung Cancer Principal Investigator: Ruth McCorkle |
| The CHIPS Trial (Control of Hypertension In Pregnancy Study) Disease/Condition: Gestational Hypertension Principal Investigator: Anna Katerina Sfakianaki |
| The Effects of ?-9-THC and Naloxone in Humans Disease/Condition: Healthy Principal Investigator: Deepak Cyril D''Souza |
| The Effects of Cannabidiol and ?-9-THC in Humans Disease/Condition: Healthy Principal Investigator: Mohini Ranganathan, M.D |
| The MagnaSafe Registry: Determining the Risks of Magnetic Resonance Imaging (MRI) in the Presence of Pacemakers and Implantable Cardioverter Defibrillators (ICDs) Disease/Condition: Implantable Cardioverter Defibrillator Implanted | Need for MRI Imaging With Pacemaker or Principal Investigator: Rachel Lampert, MD |
| The PhenoGenetic Project - Yale University Disease/Condition: Healthy Subjects Principal Investigator: Stephanie C Eisenbarth |
| The Role of Stress in Self-Control, Coping, and Emotion Regulation Disease/Condition: Chronic Stress. Principal Investigator: Rajita Sinha, PhD |
| The Testosterone Trial in Older Men Disease/Condition: Andropause Principal Investigator: Thomas Gill, M.D. |
| The Use of Propranolol to Block Memory Reconsolidation in PTSD Disease/Condition: Posttraumatic Stress Disorders Principal Investigator: Aikins, Deane |
| Tobacco Approach Avoidance Training for Adolescent Smokers-2 Disease/Condition: Tobacco Use Disorder Principal Investigator: Suchitra Krishnan-Sarin, Ph.D. |
| TODAY Genetics Study Disease/Condition: Type 2 Diabetes Principal Investigator: Sonia Caprio, MD |
| Transcranial Magnetic Stimulation (TMS) and Obsessive Compulsive Disorder (OCD) Disease/Condition: Obsessive-Compulsive Disorder |
| Transitions: Linkages From Jail To Community Disease/Condition: HIV | HIV Infections | Substance Abuse Principal Investigator: Frederick Altice, MD |
| Treatment of Binge Eating in Obese Patients in Primary Care Disease/Condition: Binge Eating | Obesity Principal Investigator: Grilo, Carlos M |
| Treatment of Refractory Schizophrenia With Riluzole Disease/Condition: Schizoaffective | Schizophrenia Principal Investigator: Zimolo, Zoran |
| Treatment Study of Sleep Apnea Among Patients With Transient Ischemic Attack and Minor Stroke Disease/Condition: Stroke | Transient Ischemic Attack Principal Investigator: Christine Won |
| Treatment With Mecamylamine in Smoking and Non-smoking Alcohol Dependent Patients Disease/Condition: Alcoholism Principal Investigator: Petrakis, Ismene Leonida |
| Understanding and Treating Disorders of Female Sexual Dysfunction Disease/Condition: Female Sexual Dysfunction Principal Investigator: Marsha Kathleen Guess |
| Varenicline on Reward Responses and Cognition in Adolescent Smokers Disease/Condition: Tobacco Use Disorders Principal Investigator: Suchitra Krishnan-Sarin, Ph.D. |
| Varenicline Treatment of Alcohol Dependence in Smokers Disease/Condition: Alcohol Abuse | Alcohol Dependence | Smoking Principal Investigator: Stephanie Samples O''Malley |
| Ventavis® Registry Protocol Disease/Condition: Pulmonary Arterial Hypertension Principal Investigator: Terence Keith Trow |
| Vincristine, Dactinomycin, and Doxorubicin With or Without Radiation Therapy or Observation Only in Treating Younger Patients Who Are Undergoing Surgery for Newly Diagnosed Stage I, Stage II, or Stage III Wilms Tumor Disease/Condition: Kidney Cancer Principal Investigator: Kupfer, Gary |
| Vinorelbine Tartrate and Cyclophosphamide in Combination With Bevacizumab or Temsirolimus in Treating Patients With Recurrent or Refractory Rhabdomyosarcoma Disease/Condition: Adult Rhabdomyosarcoma | Alveolar Childhood Rhabdomyosarcoma | Mixed Childhood Rhabdomyosarcoma | Pleomorphic Childhood Rhabdomyosarcoma | Previously Treated Childhood Rhabdomyosarcoma | Recurrent Adult Soft Tissue Sarcoma | Recurrent Childhood Rhabdomyosarcoma Principal Investigator: Nina Kadan-Lottick |
| Web Based Renal Transplant Patient Medication Education Disease/Condition: Renal Transplant Recipients |
| Web-based CBT4CBT for Alcohol Disease/Condition: Alcohol Abuse or Dependence Principal Investigator: Kathleen Carroll, PhD |
| Women With Cancer: An Exercise Study to Promote Health Disease/Condition: Bone Loss | Cancer Principal Investigator: M. Tish Knobf, PhD |
| Women's Experience with Triple Negative Breast Cancer Disease/Condition: Breast Cancer Principal Investigator: Yasemin Turkman |
| Yoga for Pain and Opioid Dependence Disease/Condition: Chronic Pain | Opioid Addiction Principal Investigator: Declan T Barry, Ph.D. |
| Zenith(R) Low Profile AAA Endovascular Graft Clinical Study Disease/Condition: Abdominal Aortic Aneurysms | Aorto-iliac Aneurysms | Iliac Aneurysms Principal Investigator: Muhs, Bart Edward |
| Ziprasidone in the Psychosis Prodrome Disease/Condition: Psychosis Prodrome Principal Investigator: Woods, Scott W |
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