The purpose of this study is to test the effects of cannabinoids on pain response using a variety of human experimental pain models. The study has two phases, Phase 1 (in which THC is administered after capsaicin in healthy subjects), and Phase 2 (separate sub-studies in which chronic cannabis smokers are enrolled and the capsaicin is administered after rather than before THC).

 

Upon completion of all study visits and related procedures, participants will be compensated $650 for their time and effort.