Rapamycin as Treatment for Autosomal Dominant Polycystic Kidney Disease (ADPKD): The Role of Biomarkers in Predicting a Response to Therapy
Conditions
Autosomal Dominant Polycystic Kidney Disease
What is the purpose of this trial?
Currently the only approved use for rapamycin (sirolimus) is for immunosuppression after renal transplantation.
This trial is designed to determine whether rapamycin is safe and effective treatment for patients with polycystic kidney disease (ADPKD). Patients will be followed by volumetric magnetic resonance imaging (MRI) to observe for change in kidney (and cyst) size. Blood and urine samples will also be collected to evaluate for change in biomarkers with treatment.
Participation Guidelines
- Age:
- 18 Years - 70 Years
- Gender:
- Both
Click here for detailed information about who can participate in this trial.
- Sponsor:
- Yale University
- Dates:
- June 2009
- Last Updated:
- June 28, 2010
- Study HIC#:
- 0903004934
Clinicaltrials.gov ID: NCT00920309
