Prazosin for Treatment of Patients With Alcohol Dependence (AD) and Post Traumatic Stress Disorder (PTSD).
What is the purpose of this trial?
Prazosin is an alpha-1 adrenergic receptor antagonist that has been used successfully in the treatment of trauma nightmares and sleep disturbance in combat veterans with PTSD, and alcohol dependence.
The objective of this study is to evaluate the efficacy of prazosin (16mg) versus placebo in reducing alcohol consumption and decreasing symptoms of PTSD in patients with comorbid AD and PTSD.
- 21 Years - 65 Years
- Elizabeth Ralevski
- January 2009
- Last Updated:
- January 26, 2012
- Study HIC#:
Clinicaltrials.gov ID: NCT00744055