Research

Key to our mission is innovative research in three areas of expertise at Yale:

  1. Vascular cell signal transduction leading to inflammation, angiogenesis and vascular remodeling;
  2. Design and implementation of cell based, engineered blood vessels and tissues; and
  3. Genetic and translational insights into vascular diseases.
Vascular Development, image courtesy of Wang Min, PhDOne of the major interests in VBT is to understand the mechanisms for vascular development and remodeling. Image shown above is a normal mouse embryo at embryonic day 13.5 linked with placenta and yolk sac by blood vessels (red). Image on the right is a mutant mouse embryo with delayed vascular development. Corresponding mouse retina blood vessels on postnatal day 4 are shown on the top. Image courtesy of Wang Min, PhD. 

One of the major interests in VBT is to understand the mechanisms for vascular development and remodeling. Image shown above is a normal mouse embryo at embryonic day 13.5 linked with placenta and yolk sac by blood vessels (red). Image on the right is a mutant mouse embryo with delayed vascular development. Corresponding mouse retina blood vessels on postnatal day 4 are shown on the top. Image courtesy of Wang Min, PhD.