Richard A Flavell PhD, FRS
Sterling Professor of Immunobiology; Investigator, Howard Hughes Medical Institute; Department Chair, Immunobiology
Dr. Flavell is Sterling Professor of Immunobiology at Yale University School of Medicine, and an Investigator of the Howard Hughes Medical Institute. He received his B.Sc. (Honors) in 1967 and Ph.D. in 1970 in biochemistry from the University of Hull, England, and performed postdoctoral work in Amsterdam (1970-72) with Piet Borst and in Zurich (1972-73) with Charles Weissmann. Before accepting his current position in 1988, Dr. Flavell was first Assistant Professor (equivalent) at the University of Amsterdam (1974-79); then Head of the Laboratory of Gene Structure and Expression at the National Institute for Medical Research, Mill Hill, London (1979-82); and subsequently President and Chief Scientific Officer of Biogen Research Corporation, Cambridge, Massachusetts (1982-88). Dr. Flavell is a fellow of the Royal Society, a member of the National Academy of Sciences as well as the Institute of Medicine. Richard Flavell uses transgenic and gene-targeted mice to study Innate and Adaptive immunity, T cell tolerance and activation in immunity and autoimmunity,apoptosis, and regulation of T cell differentiation.
- Mouse Model to Evaluate Attenuated Vaccine Candidates
The primary objective of this proposal is to generate a humanized mouse model in which critical components of the human immune system replace the homologous regions of the mouse.
Education & Training
- Hull University (1970)
- Postdoctoral Fellow with Professor Piet Borst
- University of Amsterdam, in the European Programme of the Royal Society of Great Britain (1970 - 1972)
- EMBO Postdoctoral Fellow with Prof. C. Weissmann
- Universitat Zurich, Institut fur Molekularbiologie (1972 - 1973)
Honors & Recognition
- The Vilcek Prize in Biomedical Science
Vilcek Foundatioin (2013)
- The William B. Coley Award for Distinguished Research in Basic and Tumor Immunology
Cancer Research Institute (2012)