Christopher Kane Breuer, MD

Associate Professor of Surgery (Pediatrics) and of Pediatrics; Director of Tissue Engineering

Departments & Organizations

Yale Medical Group

Stem Cell Center, Yale

Cancer Center, Yale: Pediatric Hematology & Oncology Program: Pediatric Surgery

Vascular Biology and Therapeutics Program

Pediatrics: Pediatric Thyroid Center | Pediatric Specialty Center | Pediatric Cardiovascular Surgery | Pediatric Surgery

Surgery: Pediatric Surgery


Research Interests

Cardiovascular tissue engineering to develop neo-tissue for reconstructive surgical applications; Director of Tissue Engineering, particularly cardiovascular tissue engineering to develop neo-tissue for reconstructive surgical applications more...


Education

  • B.A., College of the Holy Cross, 1986
  • M.D., Brown-Dartmouth Medical Program, 1990

Selected Publications

  • Roh JD, Sawh-Martinez R, Brennan MP, Jay SM, Devine L, Rao DA, Yi T, Mirensky TL, Nalbandian A, Udelsman B, Hibino N, Shinoka T, Saltzman WM, Snyder E, Kyriakides TR, Pober JS, Breuer CK. Tissue-engineered vascular grafts transform into mature blood vessels via an inflammation-mediated process of vascular remodeling. Proc Natl Acad Sci U S A. 2010. 107(10):4669-74.
  • Hibino N, Villalona G, Pietris N, Duncan DR, Schoffner A, Roh JD, Dobrucki LW, Mejias D, Sawh-Martinez R, Harrington JK, Sinusas A, Krause DS, Kyriakides T, Saltzman WM, Pober JS, Shinoka T, Breuer CK. Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. FASEB J. 2011. 20(8):2731-9.
  • Hibino N, Yi T, Duncan DR, Rathore A, Dean E, Naito Y, Dardik A, Kyriakides T, Madri J, Pober JS, Shinoka T, Breuer Ck. A critical role for macrophages in neovessel formation and the development of stenosis in tissue-engineered vascular grafts. FASEB J. 2011 [epub ahead of print]

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