Clinical Trials

Bladder Cancer

10
(Novartis Signature) Modular phase II study to link targeted therapy to patients with pathway activated tumors: Module 4 - LGX818 for patients with BRAFV600 mutated tumors
Disease/Condition: Bladder | Brain and Nervous System | Breast - Female | Esophagus | Eye and Orbit | Kidney | Larynx | Lip, Oral Cavity and Pharynx | Liver | Lung | Melanoma, skin | Other Skin | Ovary | Pancreas | Prostate | Rectum | Small Intestine | Soft Tissue | Stomach
Principal Investigator: Joseph Paul Eder
A Phase I Study of the Safety and Pharmacokinetics of Escalating Doses of AGS15E Given as Monotherapy in Subjects with Metastatic Urothelial Cancer
Disease/Condition: Bladder
Principal Investigator: Daniel Petrylak
A Phase I, Open-label, dose-escalation study of the safety and pharmacokinetics of MPDL3280A administered intravenously as a single agent to patients with locally advanced or metastatic solid tumors or hematologic malignancies
Disease/Condition: Bladder | Brain and Nervous System | Breast - Female | Colon | Esophagus | Kidney | Larynx | Lip, Oral Cavity and Pharynx | Liver | Lung | Melanoma, skin | Multiple Myeloma | Non-Hodgkin's Lymphoma | Other Male Genital | Pancreas | Prostate | Rectum | Soft Tissue | Stomach | Thyroid
Principal Investigator: Roy Herbst
A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Disease/Condition: Bladder
Principal Investigator: Daniel Petrylak
A Randomized, Phase 2, Open-Label Study Evaluating DN24-02 as Adjuvant Therapy in Subjects with High Risk HER2+ Urothelial Carcinoma
Disease/Condition: Bladder | Cancer
Principal Investigator: Hari Deshpande

Kidney Cancer

Prostate Cancer

Kidney & Urinary Tract

10
A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor
Disease/Condition: Kidney Transplantation Cytomegalovirus (CMV) Negative Recipients
Principal Investigator: Peter Yoo
Assessment of worldwide acute kidney injury, renal angina and epidemiology (The AWARE Study)
Disease/Condition: Acute Kidney Injury
Principal Investigator: E. Vincent Faustino
Evaluation of the Benefits and Risks in Maintenance Renal Transplant Recipients Following Conversion to Nulojix (belatacept)-based Immunosuppression
Disease/Condition: Kidney Transplant
Principal Investigator: Sanjay Kulkarni
Open-Label Tolvaptan Study in Subjects With ADPKD (TEMPO 4/4)
Disease/Condition: Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Neera Dahl
SYNERGY: A Randomized, Double-Bind, Parallel-Group, Placebo- and Active-Controlled, Multi-Center Study to Evaluate the Efficacy, Safety and Tolerability of Combinations of Solifenacin Succinate and Mirabegron Compared to Solifenacin Succinate and Mirabegron Monotherapy in the Treatment of Overactive Bladder Protocol for Phase 3 Study of Solifenacin Succinate and Mirabegron (EB178)
Disease/Condition: Overactive Bladder
Principal Investigator: Harris Foster
The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue
Disease/Condition: Brown Adipose Tissue
Principal Investigator: Robert Sherwin

Men's Health

10
A Phase 3, Open Label, Non-Randomized, Clinical Trial to Evaluate the Efficacy and Safety of FE999303 Testosterone Gel in Adult Hypogonadal Males
Disease/Condition: Adult Male Hypogonadism
Principal Investigator: Stanton Honig
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Disease/Condition: Cannabis Dependence | Family History of Alcoholism | Prodromal for Psychotic Illness | Schizophrenia
Principal Investigator: D. D'Souza

Women's Health

10
A Trial of Cranberry Capsules for Urinary Tract Infection Prevention in Nursing Home Residents
Disease/Condition: Bacteriuria
Principal Investigator: Manisha Juthani-Mehta
Compromised Microcirculation in Women With Polycystic Ovary Syndrome
Disease/Condition: Polycystic Ovary Syndrome
Principal Investigator: Nina Stachenfeld
Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
Disease/Condition: Child Abuse and Neglect | Maternal Substance Abuse
Principal Investigator: Nancy Suchman
Study of the Elevate Anterior and Apical Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
Disease/Condition: Anterior Pelvic Organ Prolapse | Apical Pelvic Organ Prolapse
Principal Investigator: Richard Bercik
Study of the Elevate Apical and Posterior Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
Disease/Condition: Posterior and Apical Pelvic Organ Prolapse | Posterior Pelvic Organ Prolapse
Principal Investigator: Richard Bercik
Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents
Disease/Condition: Insulin Resistance | Obesity
Principal Investigator: Romy Kursawe
Understanding and Treating Disorders of Female Sexual Dysfunction
Disease/Condition: Female Sexual Dysfunction
Principal Investigator: Marsha Kathleen Guess