Clinical Trials

Bladder Cancer

10
(Novartis Signature) Modular phase II study to link targeted therapy to patients with pathway activated tumors: Module 4 - LGX818 for patients with BRAFV600 mutated tumors
Disease/Condition: Bladder | Brain and Nervous System | Breast - Female | Esophagus | Eye and Orbit | Kidney | Larynx | Lip, Oral Cavity and Pharynx | Liver | Lung | Melanoma, skin | Other Skin | Ovary | Pancreas | Prostate | Rectum | Small Intestine | Soft Tissue | Stomach
Principal Investigator: Joseph Paul Eder
A Phase I Study of the Safety and Pharmacokinetics of Escalating Doses of AGS15E Given as Monotherapy in Subjects with Metastatic Urothelial Cancer
Disease/Condition: Bladder
Principal Investigator: Daniel Petrylak
A Phase I, Open-label, dose-escalation study of the safety and pharmacokinetics of MPDL3280A administered intravenously as a single agent to patients with locally advanced or metastatic solid tumors or hematologic malignancies
Disease/Condition: Bladder | Brain and Nervous System | Breast - Female | Colon | Esophagus | Kidney | Larynx | Lip, Oral Cavity and Pharynx | Liver | Lung | Melanoma, skin | Multiple Myeloma | Non-Hodgkin's Lymphoma | Other Male Genital | Pancreas | Prostate | Rectum | Soft Tissue | Stomach | Thyroid
Principal Investigator: Roy Herbst
A Phase II, Multicenter, Single-Arm Study of MPDL3280A in Patients With Locally Advanced or Metastatic Urothelial Bladder Cancer
Disease/Condition: Bladder
Principal Investigator: Daniel Petrylak
A Randomized, Phase 2, Open-Label Study Evaluating DN24-02 as Adjuvant Therapy in Subjects with High Risk HER2+ Urothelial Carcinoma
Disease/Condition: Bladder | Cancer
Principal Investigator: Hari Deshpande
Gemcitabine Hydrochloride and Cisplatin With or Without Bevacizumab in Treating Patients With Advanced Urinary Tract Cancer
Disease/Condition: Bladder | Distal Urethral Cancer | Metastatic Transitional Cell Cancer of the Renal Pelvis and Ureter | Proximal Urethral Cancer | Recurrent Bladder Cancer | Recurrent Prostate Cancer | Recurrent Transitional Cell Cancer of the Renal Pelvis and Ureter | Recurrent Urethral Cancer | Stage IV Bladder Cancer | Stage IV Prostate Cancer | Transitional Cell Carcinoma of the Bladder | Urethral Cancer Associated With Invasive Bladder Cancer
Principal Investigator: Hari Deshpande

Kidney Cancer

Prostate Cancer

Kidney & Urinary Tract

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A Study to Evaluate the Efficacy and Safety of a Vaccine, ASP0113, in Cytomegalovirus (CMV)-Seronegative Kidney Transplant Recipients Receiving an Organ From a CMV-Seropositive Donor
Disease/Condition: Kidney Transplantation Cytomegalovirus (CMV) Negative Recipients
Principal Investigator: Peter Yoo
Assessment of worldwide acute kidney injury, renal angina and epidemiology (The AWARE Study)
Disease/Condition: Acute Kidney Injury
Principal Investigator: E. Vincent Faustino
Evaluation of the Benefits and Risks in Maintenance Renal Transplant Recipients Following Conversion to Nulojix (belatacept)-based Immunosuppression
Disease/Condition: Kidney Transplant
Principal Investigator: Sanjay Kulkarni
Open-Label Tolvaptan Study in Subjects With ADPKD (TEMPO 4/4)
Disease/Condition: Autosomal Dominant Polycystic Kidney Disease
Principal Investigator: Neera Dahl
The Norepinephrine Transporter: A Novel Target for Imaging Brown Adipose Tissue
Disease/Condition: Brown Adipose Tissue
Principal Investigator: Robert Sherwin

Men's Health

10
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Disease/Condition: Cannabis Dependence | Family History of Alcoholism | Prodromal for Psychotic Illness | Schizophrenia
Principal Investigator: D. D'Souza

Women's Health

10
A Trial of Cranberry Capsules for Urinary Tract Infection Prevention in Nursing Home Residents
Disease/Condition: Bacteriuria
Principal Investigator: Manisha Juthani-Mehta
Compromised Microcirculation in Women With Polycystic Ovary Syndrome
Disease/Condition: Polycystic Ovary Syndrome
Principal Investigator: Nina Stachenfeld
Stage I Randomized Trial of Mentalization-Based Therapy for Substance Using Mothers of Infants and Toddlers
Disease/Condition: Child Abuse and Neglect | Maternal Substance Abuse
Principal Investigator: Nancy Suchman
Study of the Elevate Anterior and Apical Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
Disease/Condition: Anterior Pelvic Organ Prolapse | Apical Pelvic Organ Prolapse
Principal Investigator: Richard Bercik
Study of the Elevate Apical and Posterior Prolapse Repair System Compared to Native Tissue Repair for Pelvic Organ Prolapse
Disease/Condition: Posterior and Apical Pelvic Organ Prolapse | Posterior Pelvic Organ Prolapse
Principal Investigator: Richard Bercik
Study to Investigate Benefits of Weight Loss in Young Adults and Adolescents
Disease/Condition: Insulin Resistance | Obesity
Principal Investigator: Romy Kursawe
Understanding and Treating Disorders of Female Sexual Dysfunction
Disease/Condition: Female Sexual Dysfunction
Principal Investigator: Marsha Kathleen Guess