Charles N Walker, MD

Assistant Professor of Urology

Research Organizations

Cancer Center, Yale

Urology

Research Summary

High-risk prostate cancer, erectile dysfunction and cardiovascular disease, geriatrics, health disparity, and the vascular biology of erectile function. Dr. Walker has held a grant from the American Geriatrics Society and is principal investigator for a high risk prostate cancer clinical trials and co -investigator on an erectile dysfunction study at the VA Healthcare System in West Haven, Connecticut.

Extensive Research Description

Novel imaging modalities in the evaluation of renal masses high-risk localized prostate cancer

“A Multicenter Clinical Study Of the Sonablate 500 for the Treatment of Locally Recurrent Prostate Caner with HIFU (STAR Trial).” Investigators: Uchio E, Walker C. Sponsor: Focus Surgery, US HIFU. VA Connecticut Healthcare System. Surgical Service. West Haven, CT. (04/10-present).

“A Randomized Phase III Study of Neoadjuvant Docetaxel and Androgen Deprivation Prior to Androgen Deprivation Versus Immediate Radical Prostatectomy in Patients With High-Risk, Clinically Localized Prostate Cancer.” Investigators: Uchio E, Rose M, Rome L, Deshpande H, Gettinger S, Lee J, Aggarwal S, Choromanska O, Walker C. Sponsor: CALGB. VA Connecticut Healthcare System. Surgical Service. West Haven, CT. (12/06-present).

“Chemotherapy After Prostatectomy (CAP) For High Risk Prostate Carcinoma: A Phase III Randomized Study.” Investigators: Uchio E, Rose M, Rome L, Deshpande H, Gettinger S, Lee J, Aggarwal S, Choromanska O, Walker C. Sponsor: VA Cooperative Studies Program. VA Connecticut Healthcare System. Surgical Service. West Haven, CT. (4/06-present).

“A Randomized Double Blind, Placebo Controlled Phase III Study of Early Versus Standard Zoledronic Acid to Prevent Skeletal Related Events in Men With Prostate Cancer Metastatic to Bone.” Investigators: Rose M, Rome L, Deshpande H, Gettinger S, Lee J, Uchio E, Aggarwal S, Choromanska O, Walker C. Sponsor: CALGB. VA Connecticut Healthcare System. Cancer Center. West Haven, CT. (3/06-present).

“The effect of Acute Inflammation on Guinea Pig Bladder Mucin Expression.” Advisor: Robert Weiss M.D. Yale University School of Medicine, Department of Surgery, Section of Urology. (7/02-12/02).

Selected Publications

  • The Link Between Vasculogenic Erectile Dysfunction, Coronary Artery Disease, and Peripheral Artery Disease: Role of Metabolic Factors and Endovascular Therapy Stephanie M. Meller, BA1, Erik Stilp, MD2, Charles N. Walker, MD1, Carlos Mena-Hurtado, MD2 J I
  • Rivera AD, Walker CN, Bleustein C, Choi B, Poppas DP, Felsen D. Enhanced adenoviral vector mediated gene transfer using human albumin solder. Lasers Surg Med. 2002, 30(4): 313-19.
  • Bleustein CB, Walker CN, Felsen D, Poppas DP. Semi-solid albumin solder improved mechanical properties for laser tissue welding. Lasers Surg Med. 2000, 27(2): 140-46.
  • Ghidini A, Spong CY, Grier RE, Walker CN, Pezzullo JC. Is maternal serum triple screening a better predictor of Down Syndrome in female than in male fetuses? Prenatal Diagn. 1998, 18(2): 123-26.
  • CY, Ghidini A, Ossandon M, Walker CN, Pezzullo JC. Are the cytokines interleukin-6 and angiogenin stable in frozen amniotic fluid? Am J Obstet Gynecol. 1998, 178(4): 783-86.
  • Spong CY, Ghidini A, Walker CN, Ossandon M, Pezzullo JC. Elevated maternal serum midtrimester alpha-fetoprotein levels are associated with fetoplacental ischemia. Am J Obstet Gynecol. 1997, 177(5):1085-87.

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Contact Info

Charles N Walker, MD
Patient Care Locations
Yale Urology Smilow Cancer Hospital at Yale - New Haven
35 Park Street, Ste 4th Floor Multispecialty Care Center

New Haven, CT 06511
Cardiovascular and Sexual Health ClinicYale-New Haven Shoreline Medical Center
111 Goose Lane, Ste 2400

Guilford, CT 06437
Yale Urology330 Orchard Street, Ste 164
New Haven, CT 06511
VA Connecticut Healthcare
950 Campbell Avenue

West Haven, CT 06516
Mailing Address
PO Box 208058
New Haven, CT 06520-8058

Curriculum Vitae