Research Grants (Therapeutic Radiology PI)

2010- CURRENT


Bindra, Ranjit
Agency Grant Name Agency Number
Alex's Lemonade Stand Foundation for Childhood Cancer (ALSF) Small-molecule Screening for Novel Pediatric Glioma Radiosensitizers
YCCI Just-in time Small Pilot Grants Utilizing Core Technologies Development of Novel Methods to Assess DNA Repair Status in Primary Cell Culture Using Next Generation Sequencing
Joanna McAfee Childhood Cancer Foundation Creation of Inducible PAX3/7- FOXO1 Cell Lines for Synthetic Lethal Screening Studies
YCC Pilot High-throughput Screening for K-ras Mutant Cell Tumor Radiosensitizers
YCCC T-TARE DNA Damage Response: The Achilles Heel of HPV-associated HNSCC
The Cure Starts Now/DIPG Collaborative Pre-clinical Development of Novel DIPG Radiosensitizers
Matthew Larson Foundation Creation of Isogenic Pediatric Glioma Cell Lines for High-Throughput Drug Screening Campaigns
NIH/NCI Development of a Novel Assay to Measure DSB Repair at Endogenous Loci in Cells 1 R03 CA194967-01
Yale SPORE in Lung Cancer High-throughput screening for K-Ras mutant tumor cell radiosensitizers
American Cancer Society-Research Scholar Grant Pre-clinical Development of Mibefradil as a Novel Glioma Radiosensitizer 128352-RSG-15-197-01-TBG
Yale Cancer Center Nanoparticle-Encapsulated Radiosensitizers for the Treatment of Glioblastoma Multiforme
Musella Foundation Nanoparticle-Encapsulated Radiosensitizers for the Treatment of Glioblastoma Multiforme
The Pablove Foundation Small Molecule Screening for Novel Rhabdoid Tumor Inhibitors

Brash, Douglas
Agency Grant Name Agency Number
DOD UVL, ROS, Pigmentation, Genetic Predisposition, and Epigenetic Gene Silencing in Melanoma W81XWH-10-1-0629
NIH Yale SPORE in Skin Cancer 2 P50 CA121674-07
L'Oreal Controlling Chemiexcitation in the Skin: Exploration of Dark CPD Production in Skin
Leo Foundation Chemiexcitation in Human Disease

Carlson, David
Agency Grant Name Agency Number
YCCC Non-invasive Imaging of Tumor Hypoxia in Non-small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy
American Cancer Society Modeling Relative Biological Effectiveness and Oxygen Effects in X-ray, Proton, and Carbon Ion Radiotherapy IRG-58-012-52
Biomedical Advanced Research and Development (BARDA) within the U.S. Department of Health and Human Services In Vivo Biodosimetry using Electron Paramagnetic Resonance (EPR) Spectroscopy HHSO100201100024C

Chen, Zhe
Agency Grant Name Agency Number
NCI Prostate Edema in Permanent Interstitial Brachytherapy 5 R01 CA134627-03

Contessa, Joseph
Agency Grant Name Agency Number
ASTRO Targeting N-Linked Glycosylation to Radiosensitive Malignant Gliomas
YCCI EGFT: Therapeutic Target and Biomarker in NSCLC 5 UL1 RR024139-05
NIH A Bioluminescent Screen for Inhibitors of N-linked Glycosylation 5 R03 DA033178-02
American Cancer Society Institutional Grant Targeting N-linked Glycosylation in Non-Small Cell Lung Cancer ACS #IRG-58-012-56
American Cancer Society Research Scholar Grant Targeting N-linked Glycosylation in Non-Small Cell Lung Cancer
NIH Targeted N-linked Glycosylation to Advance Radiation Therapy 1 R01 CA172391-01A1
NIH Validation of Quantitative 11C-Erlotinib PET for Imaging EGFR-Mutant Lung Cancer 1 R01 CA195493-01




Decker, Roy
Agency Grant Name Agency Number
Merck Evaluation of Vorinostat in Combination with Palliative Radiotherapy for Patients with Stage IV Non-small Cell Lung Cancer 1 35468
RTOG-Clinical Study Radiation Therapy Oncology Group 1 U10-CA21661
SciClone Pharmaceuticals, Inc. A Phase 2b, Multi-center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV 07
Deng, Jun
Agency Grant Name Agency Number
NIH/NIBIB Tracking Organ Doses for Patient Safety in Radiation Therapy 1 R01 EB022589-01



Glazer, Peter
Agency Grant Name Agency Number
NIH Hypoxia, Genetic Instability and DNA Mismatch Repair 5 R01 ES 005775-20
NIH (YCC Core) Cancer Center Core Grant 3 P30 CA16359-32
NIH Cisplatin Damage Response and Cell-to-cell communication 5 R01 CA113344-05
NIH Research Training: Radiation Therapy, Biology, Physics 5 T32 CA009259-25
NIH DNA Repair in Cancer Biology and Therapy 5 P01 CA129186-05
NIH DNA Repair in Cancer-Administrative CORE 5 P01 CA129186-05
NIH Globin-Targeted Correction of the Human Beta Globin Gene 5 R01 HL082655-04
NIH Epigenetic Regulation in Hypoxic Cancer Cells 5 R01 CA148996-03
Doris Duke Charitable Foundation Nanoparticle-Mediated Correction of Sickle Cell Disease Mutation 2011102
NIH Novel Triplex-Engineered BRCA1-mutated Cell Lines for Research 1 R21 ES020538-01A1
Women's Health Research at Yale (WHRY) A Novel Antibody to Treat BRCA-deficient Cancers
YCCC T-TARE Novel BRCA1-deficient Cell Lines for shRNA Synthetic Lethal Screen
YCCC T-TARE Comprehensive Approaches for Understanding and Treating Melanoma Brain Metastases
NIH Cell-Penetrating Anti-DNA Antibody for Radiosensitization and Cancer Therapy 1 R01 CA168733-01A1
YCCC T-TARE Targeting miR-155 with next generation peptide nucleic acids
NIH Yale SPORE in Skin Cancer 2 P50 CA121974-07
NIH Bifunctional Antibodies for Melanoma Therapy 1 R01 CA177719-01A1

Hansen, James
Agency Grant Name Agency Number
Radiological Society of North America (RSNA) Targeting Cancer with Cell Penetrating Anti-DNA Antibody RR1108
American Cancer Society Institutional Grant Investigating Lupus Autoantibody-based Cancer Therapy ACS-IRG #58-012-55
RSNA -Research Scholar Grant Targeting Glioblastoma with a Lupus Autoantibody
YCC 2014 Pilot Targeting KRAS Mutant Cancer Cells with a Lupus Anti-guanosine Antibody
YCCI 2014 Scholar Grant Targeting Cancer with a Lupus Autoantibody
Patrys Limited Deoxymab for Cancer Therapy

Jensen, Ryan
Agency Grant Name Agency Number
American Cancer Society Institutional Grant Biochemical and Genetic Characterization of BRCA2 Sequence Variants ACS-IRG #58-012-55
Breast Cancer Alliance, INC. (BCA) Biochemical and Genetic Characterization of BRCA2 Sequence Variants
Women's Health Research at Yale (WHRY) Biochemical Identification of "BRCAness" in Breast Cancer
Ovarian Cancer Research Fund A "Cellular Switch" to Modulate BRCA2-Mediated Tumor Progression
Liu, Wu
Agency Grant Name Agency Number
The Elsa U. Pardee Foundation Radiotherapy: Monte Carlo Dosimetry Modeling
Yale Cancer Center Tumor-Targeted Delivery of Theranostic Gadolinium Nanoparticles

Low, Brooks
Agency Grant Name Agency Number
Aviex Technologies, LLC Development of an Attenuated Salmonella Vaccine for Avian Flu

Nath, Ravinder
Agency Grant Name Agency Number
NIH (YCC Core) Cancer Center Core Grant 3 P30-CA16359-32

Patel, Abhijit
Agency Grant Name Agency Number
ASTRO Ultrasensitive Measurement of Tumor DNA in Blood as a Biomarker of Radiation Response JF2011-2
YCCI Circulating Tumor-Derived DNA as a Biomarker for Cancer Treatment Response 5 UL RR024139-05
Brozman Foundation Next-Generation Sequencing for Early Detection of Ovarian Tumor DNA in Blood
American Cancer Society Assessing Cancer Treatment Response by Measurement of Circulating Tumor-Derived DNA
YCC Tumor-Derived Circulating Mutant K-ras DNA as a Biomarker for Radiation Response: A Novel Deep Sequencing Approach
YCCI TARE Tumor DNA in Blood as a Biomarker for Early Detection and Monitoring of Lung Cancer
YCCI Just-in time Small Pilot Grants Utilizing Core Technologies Tumor DNA in Blood as a Biomarker for Early Detection and Monitoring of Lung Cancer
YCC Pilot Early Detection of New or Recurrent Ovarian Cancer Using Mutant Tumor DNA in Blood
LUNGevity Detection of Early-Stage Lung Cancers via Tumor DNA in Blood
Yale SPORE in Lung Cancer Non-invasive monitoring of mutations in lung cancer via circulating tumor DNA
NIH/NCI Circulating DNA as a Marker of Treatment Efficacy and Failure in Lung Cancer 1 R01 CA197486-01A1

Rockwell, Sara
Agency Grant Name Agency Number
NIH DNA Repair in Cancer 5 P01 CA129186-05
NIH DNA Repair in Cancer-STIMULUS FUNDS 3 P01 CA129186-04S2
NIH/NCCR Clinical and Translational Science Award (YCCI) UL1 RR 023423

Rogers, Faye
Agency Grant Name Agency Number
NIH Altered Helical Structures: Repair and Induction of Genomic Instability 5 K22 CA120049-03
NIH Altered Helical Structures: Repair STIMULUS FUNDS 3 K22 CA120049-03S1
Breast Cancer Alliance, INC. (BCA) Gene Targeted Apoptosis as a Therapeutic Strategy for HER2-Positive Breast Cancer 278479
YCCC Pilot Novel Therapeutic Strategy for the Treatment of Herceptin Resistant Breast Cancers
NIH/NCI Gene-Targeted Apoptosis as a Treatment for HER2- Positive Breast Cancer 1 R21 CA185192-01A1

Sweasy, Joann
Agency Grant Name Agency Number
NIH-CORE B DiMaio-DNA Polymerase B & Cellular Transformation 3 P01 CA16038-36
NIH Characterization of a DNA Polymerase beta deficient mouse 5 R01 CA116753-05
NIH DNA Polymerase Beta and Breast Cancer 1 R21 CA127097-02
NIH DNA Repair in Cancer 1 P01 CA129186-05
Subcontract-USC DNA Polymerase Fidelity Mechanisms: Theory and Experiment 5 U19 CA10501-08
NIH DNA Polymerase Beta And Mutagenesis-Fidelity 5 R01 CA080830-16
Women's Health Res at Yale Modeling Breast Cancer Treatment in Humanized Mice
YCC Modeling Breast Cancer Treatment in Humanized Mice
NIH DNA Polymerase Beta Variants and Cancer 5 R01 ES019179-03
NIH-UVM Structure and Function of DNA Repair Enzymes 5 P01 CA098993-07
YCCI-TARE The DNA Repair Landscape of Breast Cancer
NIH Characterization of a DNA Polymerase Beta Deficient Mouse 2 R01 CA116753-06A1
NIH Base-Excision Repair and Autoimmunity 1 R21 AI097756-01
YCCI-SPIRIT Uncovering the DNA Repair Landscape in Colon Cancer
NIH Yale SPORE in Skin Cancer 2 P50 CA121974-07
NIH/NIAID The Role of a PARP1 Genetic Variant in Development of Lupus 1 R21 AI124055-01

Wilson, Lynn
Agency Grant Name Agency Number
NCI Racial Disparities in Clinical Outcomes and the Therapeutic Use of Radiotherapy for Patients with Cutaneous Lymphoma 1 R03 CA151153-01
Stanford Contract A Multicancer, Open-Label, Radomized, Phase I/II Study Evaluating the Safety and Efficacy of Low-Dose (12Gy)Total Skin Electron Beam Therapy (TSEBT) Combined with Verinostat versus Low Dose TSEBT Monotherapy in Mycosis Fungodes (MF) 27136490-50891-B

Yu, James
Agency Grant Name Agency Number
American Cancer Society Institutional Research Grant The PICK Pilot trial: Prostate Intensity Modulated Radiation Therapy versus Cyberknife Health Related Quality of Life (HRQoL) Trial IRG-58-012-52
YCCI Scholar Award Stereotactic Radiosurgery for Older Cancer Patients with Early Stage Non-small Cell Lung Cancer: National Patterns of Care and Comparison with Surgery
21st Century Oncology Research Gift
PhRMA Foundation Quantifying the Benefit of Modern Cancer Therapy for Elderly Patients: A Population Level Measurement
Yale Cancer Center Reanalyzing the TARGIT-A Trial: A Novel Data Sharing Collaboration

Yun, Zhong
Agency Grant Name Agency Number
NIH Role of Hypoxia in the Regulation of Cancer Cell Differentiation 5 R01 CA125021-05
NIH Epigenetic Regulation in Hypoxic Cancer Cells 1 R01 CA148996-02
YCCI-TARE Stromal Microenvironment and Regulation of Clonal Expansion of Breast Cancer
AHA Adiposed Signaling and Cardiomyopathy 11GRNT7970029
State of CT-STEM Cell Research Grant Hypoxia and Maintenance of Human Cancer Stem Cells
YCC Pilot A Genetic Oxygen-Sensing Mouse Model
NIH Malignant and Radioresistant Nature of Hypoxic Tumor Cells 1 R01 CA178254-01A1