Research Grants (Therapeutic Radiology PI)

2010- CURRENT


Bindra, Ranjit
AgencyGrant NameAgency Number
Alex's Lemonade Stand Foundation for Childhood Cancer (ALSF)Small-molecule Screening for Novel Pediatric Glioma Radiosensitizers
YCCI Just-in time Small Pilot Grants Utilizing Core Technologies
Development of Novel Methods to Assess DNA Repair Status in Primary Cell Culture Using Next Generation Sequencing

Joanna McAfee Childhood Cancer FoundationCreation of Inducible PAX3/7- FOXO1 Cell Lines for Synthetic Lethal Screening Studies
YCC PilotHigh-throughput Screening for K-ras Mutant Cell Tumor Radiosensitizers
YCCC T-TAREDNA Damage Response: The Achilles Heel of HPV-associated HNSCC
The Cure Starts Now/DIPG Collaborative    Pre-clinical Development of Novel DIPG Radiosensitizers
Matthew Larson FoundationCreation of Isogenic Pediatric Glioma Cell Lines for High-Throughput Drug Screening Campaigns

Brash, Douglas
AgencyGrant NameAgency Number

DOD

UVL, ROS, Pigmentation, Genetic Predisposition, and Epigenetic Gene Silencing in MelanomaW81XWH-10-1-0629
NIH    Yale SPORE in Skin Cancer2 P50 CA121674-07

Carlson, David
AgencyGrant NameAgency Number
YCCCNon-invasive Imaging of Tumor Hypoxia in Non-small Cell Lung Cancer Patients Undergoing Stereotactic Body Radiotherapy
American Cancer Society
Modeling Relative Biological Effectiveness and Oxygen Effects in X-ray, Proton, and Carbon Ion RadiotherapyIRG-58-012-52
Biomedical Advanced Research and Development (BARDA) within the U.S. Department of Health and Human ServicesIn Vivo Biodosimetry using Electron Paramagnetic Resonance (EPR) Spectroscopy                                        
HHSO100201100024C

Chen, Zhe
AgencyGrant NameAgency Number
NCIProstate Edema in Permanent Interstitial Brachytherapy5 R01 CA134627-03

Contessa, Joseph
AgencyGrant NameAgency Number
ASTROTargeting N-Linked Glycosylation to Radiosensitive Malignant Gliomas
YCCIEGFT: Therapeutic Target and Biomarker in NSCLC5 UL1 RR024139-05
NIHA Bioluminescent Screen for Inhibitors of N-linked Glycosylation5 R03 DA033178-02
American Cancer Society Institutional GrantTargeting N-linked Glycosylation in Non-Small Cell Lung CancerACS #IRG-58-012-56
American Cancer Society Research Scholar GrantTargeting N-linked Glycosylation in Non-Small Cell Lung Cancer
NIH                
Targeted N-linked Glycosylation to Advance Radiation Therapy    1 R01 CA172391-01A1

Decker, Roy
AgencyGrant NameAgency Number
MerckEvaluation of Vorinostat in Combination with Palliative Radiotherapy for Patients with Stage IV Non-small Cell Lung Cancer1 35468

RTOG-Clinical Study


Radiation Therapy Oncology Group


1 U10-CA21661


SciClone Pharmaceuticals, Inc.A Phase 2b, Multi-center, Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of Three Different Doses of SCV 07

Glazer, Peter
AgencyGrant NameAgency Number
NIHHypoxia, Genetic Instability and DNA Mismatch Repair5 R01-ES 005775-20
NIH (YCC Core)Cancer Center Core Grant3 P30 CA16359-32 
NIHCisplatin Damage Response and Cell-to-cell communication5 R01-CA113344-05
NIHResearch Training: Radiation Therapy, Biology, Physics5-T32-CA009259-25 
NIHDNA Repair in Cancer Biology and Therapy5 P01-CA129186-05
NIHDNA Repair in Cancer-Administrative CORE5 P01-CA129186-05
NIHGlobin-Targeted Correction of the Human Beta Globin Gene5 R01 HL082655-04
NIHEpigenetic Regulation in Hypoxic Cancer Cells5 R01CA148996-03
Doris Duke Charitable FoundationNanoparticle-Mediated Correction of Sickle Cell Disease Mutation2011102
NIHNovel Triplex-Engineered BRCA1-mutated Cell Lines for Research1 R21 ES020538-01A1
Women's Health Research at Yale (WHRY)A Novel Antibody to Treat BRCA-deficient Cancers
YCCC T-TARENovel BRCA1-deficient Cell Lines for shRNA Synthetic Lethal Screen
YCCC T-TAREComprehensive Approaches for Understanding and Treating Melanoma Brain Metastases
NIHCell-Penetrating Anti-DNA Antibody for Radiosensitization and Cancer Therapy1 R01 CA168733-01A1
YCCC T-TARETargeting miR-155 with next generation peptide nucleic acids
NIHYale SPORE in Skin Cancer2 P50 CA121974-07

Hansen, James
AgencyGrant NameAgency Number
Radiological Society of North America (RSNA)Targeting Cancer with Cell Penetrating Anti-DNA AntibodyRR1108
American Cancer Society Institutional GrantInvestigating Lupus Autoantibody-based Cancer TherapyACS-IRG #58-012-55
RSNA -Research Scholar GrantTargeting Glioblastoma with a Lupus Autoantibody    

Jensen, Ryan
AgencyGrant NameAgency Number
American Cancer Society Institutional GrantBiochemical and Genetic Characterization of BRCA2 Sequence Variants
ACS-IRG #58-012-55
Breast Cancer Alliance, INC. (BCA)Biochemical and Genetic Characterization of BRCA2 Sequence Variants
Women's Health Research at Yale (WHRY)Biochemical Identification of "BRCAness" in Breast Cancer
Ovarian Cancer Research FundA "Cellular Switch" to Modulate BRCA2-Mediated Tumor Progression

Kidane, Dawit
AgencyGrant NameAgency Number
NIHDNA Polymerase Beta and Gastric Cancer5 K01 CA154854-02



Low, Brooks
AgencyGrant NameAgency Number
Aviex Technologies, LLCDevelopment of an Attenuated Salmonella Vaccine for Avian Flu

Nath, Ravinder
AgencyGrant NameAgency Number
NIH (YCC Core)Cancer Center Core Grant3-P30-CA16359-32

Nemec, Antonia
AgencyGrant NameAgency Number
NIHTargeting Multiple DNA Repair Pathways to Increase Drug Sensitivity1 F32 CA156843-01

Patel, Abhijit
AgencyGrant NameAgency Number
ASTROUltrasensitive Measurement of Tumor DNA in Blood as a Biomarker of Radiation ResponseJF2011-2
YCCICirculating Tumor-Derived DNA as a Biomarker for Cancer Treatment Response5 UL RR024139-05
Brozman FoundationNext-Generation Sequencing for Early Detection of Ovarian Tumor DNA in Blood
American Cancer SocietyAssessing Cancer Treatment Response by Measurement of Circulating Tumor-Derived DNA
YCCTumor-Derived Circulating Mutant K-ras DNA as a Biomarker for Radiation Response: A Novel Deep Sequencing Approach
YCCI TARETumor DNA in Blood as a Biomarker for Early Detection and Monitoring of Lung Cancer
YCCI Just-in time Small Pilot Grants Utilizing Core TechnologiesTumor DNA in Blood as a Biomarker for Early Detection and Monitoring of Lung Cancer


Rockwell, Sara
AgencyGrant NameAgency Number
NIHDNA Repair in Cancer5 P01-CA129186-05
NIHDNA Repair in Cancer-STIMULUS FUNDS3 P01-CA129186-04S2
NIH/NCCRClinical and Translational Science Award (YCCI)UL1 RR 023423

Rogers, Faye
AgencyGrant NameAgency Number
NIHAltered Helical Structures:  Repair and Induction of Genomic Instability5-K22-CA120049-03
NIHAltered Helical Structures:  Repair STIMULUS FUNDS3-K22-CA120049-03S1
Breast Cancer Alliance, INC. (BCA)Gene Targeted Apoptosis as a Therapeutic Strategy for HER2-Positive Breast Cancer278479
YCCC PilotNovel Therapeutic Strategy for the Treatment of Herceptin Resistant Breast Cancers

Sweasy, Joann
AgencyGrant NameAgency Number
NIH-CORE BDiMaio-DNA Polymerase B & Cellular Transformation3-P01-CA16038-36
NIHCharacterization of a DNA Polymerase beta deficient mouse5 R01-CA116753-05
NIHDNA Polymerase Beta and Breast Cancer1 R21 CA127097-02
NIHDNA Repair in Cancer1 P01-CA129186-05
Subcontract-USCDNA Polymerase Fidelity Mechanisms: Theory and Experiment5 U19-CA10501-08
NIHDNA Polymerase Beta And Mutagenesis-Fidelity5 R01-CA080830-16
Women's Health Res at YaleModeling Breast Cancer Treatment in Humanized Mice
YCCModeling Breast Cancer Treatment in Humanized Mice
NIHDNA Polymerase Beta Variants and Cancer5 R01-ES019179-03
NIH-UVMStructure and Function of DNA Repair Enzymes5 P01CA098993-07
YCCI-TAREThe DNA Repair Landscape of Breast Cancer
NIHCharacterization of a DNA Polymerase Beta Deficient Mouse2 R01 CA116753-06A1
NIHBase-Excision Repair and Autoimmunity1 R21 AI097756-01
YCCI-SPIRIT
Uncoverin the DNA Repair Landscape in Colon Cancer
NIHYale SPORE in Skin Cancer2 P50 CA121974-07

Weidhaas, Joanne
AgencyGrant NameAgency Number
NIH/NCILet-7 microRNAs in Lung Cancer: Altering Growth and Radioresistance5 R01 CA131301-04
NIH/NCIDefining the Genetic Basis of the Radioresponse Using a C. elegans Tissue Model1 K08 CA124484-05
Mary Kay AsheThe Role of the KRAS-Variant in Cancer
YCCI TAREThe DNA Repair Landscape of Breast Cancer3 P30 CA16359-32
NIHMicroRNAs to Understand cause and outcome in Breast Cancer1 R01 CA157749-01A1
Subcontract-MD Anderson RSNAMicroRNA a a Prognostic Marker in Cervical Cancer Patients after Chemoradiation Analysis of Tissues from RTOG 90-01 and and Institutional Prospective Trial    12052689/98089247
LUNGevityTargeting KRAS Mutations in Lung Cancer

Wilson, Lynn
AgencyGrant NameAgency Number
NCIRacial Disparities in Clinical Outcomes and the Therapeutic Use of Radiotherapy for Patients with Cutaneous Lymphoma1 R03 CA151153-01
Stanford ContractA Multicancer, Open-Label, Radomized, Phase I/II Study Evaluating the Safety and Efficacy of Low-Dose (12Gy)Total Skin Electron Beam Therapy (TSEBT) Combined with Verinostat versus Low Dose TSEBT Monotherapy in Mycosis Fungodes (MF)27136490-50891-B

Yu, James
AgencyGrant NameAgency Number
American Cancer Society Institutional Research GrantThe PICK Pilot trial: Prostate Intensity Modulated Radiation Therapy versus Cyberknife Health Related Quality of Life (HRQoL) TrialIRG-58-012-52
YCCI Scholar AwardStereotactic Radiosurgery for Older Cancer Patients with Early Stage Non-small Cell Lung Cancer: National Patterns of Care and Comparison with Surgery
21st Century OncologyResearch Gift

Yun, Zhong
AgencyGrant NameAgency Number
NIHRole of Hypoxia in the Regulation of Cancer Cell Differentiation5 R01 CA125021-05
NIHEpigenetic Regulation in Hypoxic Cancer Cells1 R01 CA148996-02
YCCI-TAREStromal Microenvironment and Regulation of Clonal Expansion of Breast Cancer
AHAAdiposed Signaling and Cardiomyopathy11GRNT7970029
State of CT-STEM Cell Research GrantHypoxia and Maintenance of Human Cancer Stem Cells
YCC PilotA Genetic Oxygen-Sensing Mouse Model
NIHMalignant and Radioresistant Nature of Hypoxic Tumor Cells1 R01 CA178254-01A1