Clinical Research and Clinical Trials

Our clinical research programs are enhanced by the interdisciplinary collaboration that has developed in our Vascular Center. Access to clinical trials enables patients treated by our physicians to have access to the newest therapies to treat a variety of vascular diseases. Our faculty are leaders in moving forward the practice and art of vascular surgery. Active studies and clinical trials include the following:

  • Acute DVT - SONIC I Study. This trial evaluates the minimally invasive ability of an ultrasonic medical device to remove thrombus and protect patients from the late term effects of DVT, including post-thrombotic syndrome.
  • Abdominal aortic aneurysm – OVER VA Cooperative Trial – This multi-institution randomized trial compares open AAA repair to endovascular AAA repair.
  • Limb salvage – This study evaluates the impact of diabetes (and its control) on vascular disease (and its treatment) using a multidisciplinary approach to complex diabetic foot wounds.
  • Limb salvage – This trial evaluates the use of stem cells in saving threatened extremities that do not have any endovascular or surgical options.
  • Acute arterial thorombosis -Sonic II Study. This study evaluates the minimally invasive ability of an ultrasonic medical device to restore blood flow to occluded arteries and bypass grafts in an effort to achieve limb salvage.
  • Abdominal aortic aneurysm – PYTHAGORAS Study. This study evaluates a new endovascular aortic stentgraft to treat abdominal aortic aneurysm in patients who would otherwise require an open surgery.
  • Thoracic aortic dissection – This study evaluates the use or thoracic stentgrafts to repair acute aortic dissections or tears that can occur in the descending thoracic aorta.
  • Abdominal aortic aneurysm – This trial uses magnetic resonance imaging to evaluate the effect of placing aortic stentgrafts for the treatment of abdominal aortic aneurysms. Information from this trial will allow for the design and development of improved stentgrafts with better patient outcomes.
  • Abdominal aortic aneurysm – This institutional study evaluates prognostic factors that can be used to improve patient outcomes following open and endovascular abdominal aortic aneurysm repair.
  • Abdominal aortic aneurysm – This institutional study evaluates the decision making process and role of informed consent when considering AAA repair via an open or endovascular approach.
  • Carotid artery disease – This institutional study evaluates the effect of carotid artery surgery, either endovascular or traditional, on cognition.
  • Surgical education – This study evaluates the influence of the surgical clerkship in student choices on surgical careers.
  • Surgical education – This study evaluates the influence of the surgical clerkship in student choices on surgical careers.