John Alex Elefteriades, MD

William W.L. Glenn Professor of Surgery (Section of Cardiac Surgery)

Departments & Organizations

Cancer Center, Yale

Heart & Vascular Center, Yale-New Haven Hospital

Office of Student Research

Surgery: Cardiac Surgery: Thoracic Aortic Disease, Yale Center for

Yale Medical Group

Biography

Dr. John Elefteriades is the William W.L. Glenn Professor of Cardiothoracic Surgery and Director of the Aortic Institute at Yale University and Yale New-Haven Hospital. He served as Chief of Cardiac Surgery from 1995 to 2011, when he became Founding Director of the Aortic Institute at Yale-New Haven. He is among the most clinically active academic surgeons in the country.

Dr. Elefteriades graduated magna cum laude with a triple major in Physics, French and Psychology from Yale University. He received his MD degree from the Yale University School of Medicine. He trained at Yale in both general surgery and cardiothoracic surgery. After completing his training, he joined the faculty at the Yale University School of Medicine.

He performs all aspects of adult cardiac and thoracic surgery. He is a recognized authority in interventions for the failing left ventricle, including coronary artery bypass grafting, left ventricular aneurysmectomy, and artificial heart implantation. Dr. Elefteriades directs the Aortic Institute at Yale-New Haven Hospital, one of the nation's largest facilities for treatment of the dilated thoracic aorta. He conducts laboratory research in new techniques of heart transplantation. Among his research projects, he is working with Celera Diagnostics to identify the genetic mutations responsible for thoracic aortic aneurysms. Dr. Elefteriades research work into brain and spinal cord protection via hypothermia has been supported by grants from the National Science Foundation.

At his Aortic Institute, Dr. Elefteriades and his team have achieved many milestones in the understanding and treatment of aortic diseases, including: recognition of the genetic nature of thoracic aortic aneurysm, characterization of the natural history of thoracic aortic aneurysm, determination that physical and emotional stress can precipitate aortic dissection, identification of the role of MMPs in the pathogenesis of thoracic aortic aneurysms, determination of the appropriate size for surgical resection, and identification of the correspondence of mechanical deterioration of the aortic wall with clinical behavior. His team has also developed an “RNA Signature” blood test for aneurysm disease.

Dr. Elefteriades serves on multiple scientific advisory and editorial boards. He is a past President of the Connecticut Chapter of the American College of Cardiology and member of the national Board of Governors of the College. Dr. Elefteriades is also past President of the International College of Angiology. He serves on the editorial board of the American Journal of Cardiology, the Journal of Cardiac Surgery, and Cardiology. He is a member of the Thoracic Surgery Director's Association and has been named consistently in The Best Doctors in America. He is a frequently requested international lecturer, visiting professor and guest surgeon. He is the author of over 300 scientific publications on a wide range of cardiac and thoracic topics. He was selected as one of the ten best doctors in America by Men’s Health magazine. He has been featured in many dozens of print, radio, and television presentations. He has been awarded the Walter Bleifeld Memorial Award for Distinguished Contribution in Clinical Research in Cardiology, and the John B. Chang Research Achievement Award. In 2005 he was selected to deliver a lecture for the Leadership in Biomedicine Series at the Yale University School of Medicine. In 2006, he received the Socrates Award from the Thoracic Residents Association, Thoracic Surgery Directors' Association, and the Society of Thoracic Surgeons, recognizing exceptional achievement in teaching and mentorship of residents. In 2008 he was honored by the International Academy of Cardiology with a Distinguished Fellow Award. In 2011, he received the AHEPA award for Achievements in Medicine. In 2012, he was selected as one of six “Stars” to lecture at the Reunion of his Yale University undergraduate class.

Dr. Elefteriades was named the William W.L. Glenn Professor of Cardiothoracic Surgery in 2006. This endowed chair honors the memory of Dr. Elefteriades’ mentor, Dr. Glenn. Dr. Elefteriades is the author of the books House Officer Guide to ICU Care (1st, 2nd, and 3rd Editions), Advanced Treatment Options for the Failing Left Ventricle, Diseases of the Aorta, Your Heart: The Owner's Guide, The Woman’s Heart Book, and Acute Aortic Disease, and Controversies in Diseases of the Aorta. Dr. Elefteriades recently published his first fiction work, the medical mystery/ethics thriller Transplant, which was a finalist in the Next Generation Indie Book Awards as a best first novel. Dr. Elefteriades was featured in a documentary of the BBC Horizons television program for his innovative techniques applying deep hypothermia to surgery of the aortic arch. His hypothermia work has also been featured on the Italian RAI channel. His is featured again for hypothermia in a recently aired segment of the Science Channel’s acclaimed program Through the Wormhole with Morgan Freeman.

Education & Training

MD Yale University (1976)
Chief Resident Yale-New Haven Hospital
Resident Yale-New Haven Hospital
Chief Resident Yale-New Haven Hospital
Resident Yale-New Haven Hospital
Fellow Yale-New Haven Hospital, New Haven, CT
Board Certification AB of Thoracic Surgery (1985)

Honors & Recognition

  • Socrates Award Thoracic Residents Association, Thoracic Surgery Directors' Association, and Society of Thoracic Surgeons (Chicago, IL), recognizing exceptional achievement in teaching and mentorship of residents. (2006)

  • Most Outstanding Invited Faculty Presentation- "The Aneurysmatic Patient: From Large to Multifocal."6th International Advances in Understanding Aortic Diseases Meeting (2005)

  • Selected to give “Leadership in Biomedicine” lectureYale University School of Medicine (2005)

  • Professor John B. Chang Achievement AwardInternational College of Angiology (2004)

  • Walter Bleifeld Memorial Award for Distinguished Contribution in Clinical Research in CardiologyInternational Academy of Cardiology (2003)

International Activity

  • Invited faculty, “Thoracic aortic aneurysm: Reading the enemy’s playbook” 32nd Meeting of the Japanese Vascular Society Tokyo, Japan (2004)

    Invited faculty, “Thoracic aortic aneurysm: Reading the enemy’s playbook” 32nd Meeting of the Japanese Vascular Society

  • Invited lectures, “When surgery has to be advised?” & “Alternative surgical approaches for left ventricle assist devices implantation,” Instituto Clinico Humanitas’ 4th International Symposium: From Risk Factors to Heart Failure Milan, Italy (2003)

    Invited lectures, “When surgery has to be advised?” & “Alternative surgical approaches for left ventricle assist devices implantation,” Instituto Clinico Humanitas’ 4th International Symposium: From Risk Factors to Heart Failure

  • Invited faculty, 3rd Vienna Interdisciplinary Symposium on Aortic Repair (VISAR) “Natural history of aortic aneurysms” & Chair “ Surgery for Type B Dissection” Vienna, Austria (2003 - 2003)

    Invited faculty, 3rd Vienna Interdisciplinary Symposium on Aortic Repair (VISAR) “Natural history of aortic aneurysms” & Chair “ Surgery for Type B Dissection”

  • Invited Lecture, “Thoracic aortic aneurysm – a genetic disease,” 18th International Meeting on Clinical Cardiology Athens, Greece (2003 - 2003)

    Invited Lecture, “Thoracic aortic aneurysm – a genetic disease,” 18th International Meeting on Clinical Cardiology

  • Invited Lecture, International Vascular Meeting, “The natural history of aortic dissection” Paris, France (2002)

    Invited Lecture, International Vascular Meeting, “The natural history of aortic dissection”

  • Invited Faculty, Surgery for Aortic Dissection Symposium Paris, France (2002 - 2002)

    Invited Faculty, Surgery for Aortic Dissection Symposium

  • Invited Lectures: “Who should have traditional cardiac surgery?” & “CABG better than PTCA?” 3rd International Symposium: Current Issues in Heart Failure Management Milan, Italy (2002 - 2002)

    Invited Lectures: “Who should have traditional cardiac surgery?” & “CABG better than PTCA?” 3rd International Symposium: Current Issues in Heart Failure Management

  • Chairman, Valvular Heart Disease Session, 8th World Congress on Heart Failure – Mechanisms and Management Washington, United States (2002 - 2002)

    Chairman, Valvular Heart Disease Session, 8th World Congress on Heart Failure – Mechanisms and Management

  • Chairman, Awards Committee, 8 World Congress on Heart Failure – Mechanisms and Management Washington DC, United States (2002 - 2002)

    Chairman, Awards Committee, 8 World Congress on Heart Failure – Mechanisms and Management

  • Invited faculty,17th International Meeting on Clinical Cardiology Athens, Greece (2002 - 2002)

    Invited faculty,17th International Meeting on Clinical Cardiology

  • Elected as Secretary of the International College of Angiology (2002)

    Elected as Secretary of the International College of Angiology

  • Chairman Washington, United States (2002 - 2002)

    Section of Cardiovascular Surgery, 8th World Congress on Heart Failure – Mechanisms and Management

  • Invited Lecture, “ New Insights into the behavior and treatment of the thoracic aorta,” 16th International Meeting on Clinical Cardiology Athens, Greece (2001 - 2001)

    Invited Lecture, “ New Insights into the behavior and treatment of the thoracic aorta,” 16th International Meeting on Clinical Cardiology

  • Scientific Executive Committee, International Society of Heart Failure (2001)

    Scientific Executive Committee, International Society of Heart Failure

  • Invited Lecture, “Neither extreme LV dilation nor lack of ischemia on stress testing should contradict CABG for advanced ischemic cardiomyopathy,” 3rd International Congress on Coronary Artery Disease- From Prevention to Intervention Lyons, France (2000 - 2000)

    Invited Lecture, “Neither extreme LV dilation nor lack of ischemia on stress testing should contradict CABG for advanced ischemic cardiomyopathy,” 3rd International Congress on Coronary Artery Disease- From Prevention to Intervention

  • Chairperson, 3rd International Congress on Coronary Artery Disease: From Prevention to Intervention Lyon, France (2000 - 2000)

    Chairperson, 3rd International Congress on Coronary Artery Disease: From Prevention to Intervention

  • Presentation- “Conventional Cardiac Operations as Alternatives to Heart Transplantations – Long-term Results,” 7th World Congress on Heart Failure – Mechanisms and Management Vancouver, Canada (2000 - 2000)

    Presentation- “Conventional Cardiac Operations as Alternatives to Heart Transplantations – Long-term Results,” 7th World Congress on Heart Failure – Mechanisms and Management

  • Session Chair, Surgical Approaches to the Treatment of Heart Failure, 7th World Congress on Heart Failure – Mechanisms and Management Vancouver, Canada (2000 - 2000)

    Session Chair, Surgical Approaches to the Treatment of Heart Failure, 7th World Congress on Heart Failure – Mechanisms and Management

  • Invited Lecture, “Yale Perspectives on the Thoracic Aorta,” 15th International Meeting on Clinical Cardiology Athens, Greece (2000 - 2000)

    Invited Lecture, “Yale Perspectives on the Thoracic Aorta,” 15th International Meeting on Clinical Cardiology

  • Scientific Executive Committee, 7th World Congress on Heart Failure- Mechanisms & Management (2000)

    Scientific Executive Committee, 7th World Congress on Heart Failure- Mechanisms & Management

  • International Scientific Committee, 2nd International Meeting of the Onassis Surgery Center Athens, Greece (2000)

    International Scientific Committee, 2nd International Meeting of the Onassis Surgery Center

  • Abstract Review Committee, International Society of Heart Failure Vancouver, Canada (2000)

    Abstract Review Committee, International Society of Heart Failure

  • Professor Amsterdam, Netherlands (2000)

    Professor

  • Session Chair: Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles, Spinal Cord Injury Center Hamburg, Germany (1999 - 1999)

    Session Chair: Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles, Spinal Cord Injury Center

  • Invited Lecturer, “The Yale Experience.” Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles, Spinal Cord Injury Center Hamburg, Germany (1999 - 1999)

    Invited Lecturer, “The Yale Experience.” Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles, Spinal Cord Injury Center

  • Opening Ceremony Speaker, Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles. Spinal Cord Injury Center Hamburg, Germany (1999 - 1999)

    Opening Ceremony Speaker, Workshop: Functional Electrical Stimulation in Paralyzed Respiratory Muscles. Spinal Cord Injury Center

  • Scientific Executive Committee Washington, United States (1999)

    1st International Congress on Heart Disease, International Academy of Cardiology

  • Visiting Professor Amsterdam, Netherlands (1999)

    Visiting Professor

  • Invited Lecturer Washington, United States (1999 - 1999)

    1st International Congress on Heart – New Trends in Research, Diagnosis and Treatment

  • Session Chair Washington, United States (1999 - 1999)

    New Approaches to Surgical Revascularization, 1st International Congress on Heart Disease – New Trends in Research, Diagnosis and Treatment

  • Session Chair Washington, United States (1999 - 1999)

    Plenary Session, Mechanical Support, Left Ventricular Assist Devices, International Academy of Cardiology, 1st International Congress on Heart Disease – New Trends in Research, Diagnosis and Treatment

  • Invited Lecture, “Ten Year Experience with Coronary Artery Bypass Grafting in Advanced Left Ventricular Dysfunction,” 2nd International Congress on Coronary Artery Disease- From Prevention to Intervention Florence, Italy (1998 - 1998)

    Invited Lecture, “Ten Year Experience with Coronary Artery Bypass Grafting in Advanced Left Ventricular Dysfunction,” 2nd International Congress on Coronary Artery Disease- From Prevention to Intervention

  • Session Chair: Newer Surgical Techniques, 6th World Congress on Heart Failure - Mechanisms and Management Geneva, Switzerland (1998 - 1998)

    Session Chair: Newer Surgical Techniques, 6th World Congress on Heart Failure - Mechanisms and Management

  • 6th World Congress on Heart Failure, Geneva, Switzerland, Scientific Executive Committee Geneva, Switzerland (1998)

    6th World Congress on Heart Failure, Geneva, Switzerland, Scientific Executive Committee

  • Honorary Lecturer, Japanese Society for Cardiovascular Surgery Japan (1998)

    Honorary Lecturer, Japanese Society for Cardiovascular Surgery

  • Presentation- "Thoracic Aortic Surgery," 28th Annual Meeting of the Japanese Society of Cardiovascular Surgery Tokyo, Japan (1998)

    Presentation- "Thoracic Aortic Surgery," 28th Annual Meeting of the Japanese Society of Cardiovascular Surgery

  • Presentation- “Conventional Surgery as an Alternative to Transplantation for the Failing Left Ventricle.” 6th World Congress on Heart Failure - Mechanisms and Management Geneva, Switzerland (1998)

    Presentation- “Conventional Surgery as an Alternative to Transplantation for the Failing Left Ventricle.” 6th World Congress on Heart Failure - Mechanisms and Management

  • Presentation- "Advances in the Surgical Management of Thoracic Aortic Aneurysms," 2nd Panhellenic Congress of Thoracic and Cardiovascular Surgery Thessaloniki, Greece (1997 - 1997)

    Presentation- "Advances in the Surgical Management of Thoracic Aortic Aneurysms," 2nd Panhellenic Congress of Thoracic and Cardiovascular Surgery

  • Course Director: Mini-CABG Training Course Tokyo, Japan (1997)

    Course Director: Mini-CABG Training Course

  • Invited Lecture, "Should Non-Diseased Vein Grafts Be Replaced at the Time of Redo CABG," Cardiac Surgery Update '97 Athens, Greece (1997 - 1997)

    Invited Lecture, "Should Non-Diseased Vein Grafts Be Replaced at the Time of Redo CABG," Cardiac Surgery Update '97

  • Invited Lecture, "Application of Conventional Cardiac Surgical Procedures to the Patient with Left Ventricular Failure," Cardiac Surgery Update '97 Athens, Greece (1997 - 1997)

    Invited Lecture, "Application of Conventional Cardiac Surgical Procedures to the Patient with Left Ventricular Failure," Cardiac Surgery Update '97

  • Invited Lecture, "Left Ventricular Remodeling: Aneurysmectomy and Batista," Cardiac Surgery Update '97 Athens, Greece (1997 - 1997)

    Invited Lecture, "Left Ventricular Remodeling: Aneurysmectomy and Batista," Cardiac Surgery Update '97

  • Co-Chairman of Program, International Congress of Thorax Surgery, Cardiac Surgery Update '97 Athens, Greece (1997 - 1997)

    Co-Chairman of Program, International Congress of Thorax Surgery, Cardiac Surgery Update '97

  • Co-Chairman, Cardiac Surgery I Session, 39th Annual World Congress of International College of Angiology Istanbul, Turkey (1997)

    Co-Chairman, Cardiac Surgery I Session, 39th Annual World Congress of International College of Angiology

  • Chairman, "Cardiac Surgery: News and Views Session," 5th Alpe Adria Congress of Cardiology Graz, Austria (1997)

    Chairman, "Cardiac Surgery: News and Views Session," 5th Alpe Adria Congress of Cardiology

  • Scientific Executive Committee, International Academy of Cardiology, Inc. (1997)

    Scientific Executive Committee, International Academy of Cardiology, Inc.

  • Visiting Professor Cairo, Egypt (1997)

    Visiting Professor

  • Honorary Lecturer, Alpe Adria Congress of Cardiology (1997)

    Honorary Lecturer, Alpe Adria Congress of Cardiology

  • Co-President, Cardiac Surgery for the Next Millennium Athens, Greece (1997)

    Co-President, Cardiac Surgery for the Next Millennium

  • Visiting Professor Cardiff, United Kingdom (1997)

    Visiting Professor

  • Visiting Professor Tokyo, Japan (1997)

    Visiting Professor

  • Visiting Professor Fuji, Japan (1997)

    Visiting Professor

  • Visiting Professor Yokohama, Japan (1997)

    Visiting Professor

  • Invited Lecture Washington, United States (1997)

    “Advanced Surgical Modalities for LV Failure: Transplant, Cardiomyoplasty or Reduction Ventriculoplasty." International Society of Heart Failure, 5th World Congress

  • Presentation- "LV-Remodeling: Aneurysmectomy with Batista Procedures." 5th Alpe Adria Congress of Cardiology Graz, Austria (1997)

    Presentation- "LV-Remodeling: Aneurysmectomy with Batista Procedures." 5th Alpe Adria Congress of Cardiology

  • Invited Lecture Cardiff, United Kingdom (1997)

    "Left Ventricular Remodeling"

  • Presentation- "Minimally Invasive Cardiac Surgery" (1997)

    Presentation- "Minimally Invasive Cardiac Surgery"

  • Presentation- "Minimally Invasive Cardiac Surgery - Live Demonstration" Japan (1997)

    Presentation- "Minimally Invasive Cardiac Surgery - Live Demonstration"

  • Presentation- "LV Remodeling and Batista Procedure" Japan (1997)

    Presentation- "LV Remodeling and Batista Procedure"

  • Presentation- "Should Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo CABG," First International Congress on Coronary Artery Disease - From Prevention to Intervention Prague, Czech Republic (1997)

    Presentation- "Should Disease-Free Saphenous Vein Grafts Be Replaced at the Time of Redo CABG," First International Congress on Coronary Artery Disease - From Prevention to Intervention

  • Chairman Washington, United States (1997)

    "New Surgical Approaches to the Failing Heart Session," International Society of Heart Failure, 5th World Congress

  • Presentation- "Application of Conventional Operations (CABG, Valve Replacement and Left Ventricular Aneurysmectomy) to the Failing Left Ventricle," 4th World Congress on Heart Failure Jerusalem, Israel (1996 - 1996)

    Presentation- "Application of Conventional Operations (CABG, Valve Replacement and Left Ventricular Aneurysmectomy) to the Failing Left Ventricle," 4th World Congress on Heart Failure

  • Moderator of session, "Surgical Aspects, Transplantation," 4th World Congress on Heart Failure” Jerusalem, Israel (1996 - 1996)

    Moderator of session, "Surgical Aspects, Transplantation," 4th World Congress on Heart Failure”

  • Scientific Advisory Board Member for 4th World Congress on Heart Failure -Mechanisms and Management Jerusalem, Israel (1996)

    Scientific Advisory Board Member for 4th World Congress on Heart Failure -Mechanisms and Management

  • 4th World Congress on Heart Failure - Mechanisms and Management, Scientific Advisory Board Member Jerusalem, Israel (1996)

    4th World Congress on Heart Failure - Mechanisms and Management, Scientific Advisory Board Member

  • Presentation Birmingham, United Kingdom (1996 - 1996)

    "Deep Hypothermia and Circulatory Arrest Preserves Brain Morphology in Humans," Birmingham Aortic Surgery Symposium

  • Presentation Birmingham, United Kingdom (1996 - 1996)

    "What is the Appropriate Size Criterion for Resection of Thoracic Aortic Aneurysms?," Birmingham Aortic Surgery Symposium

  • Co-Moderator Cologne, Germany (1996 - 1996)

    Cardiac Surgery Session 38th Annual World Congress of the International College of Angiology

  • International College of Angiology, Co-Chairman of the Scientific Council (1995)

    International College of Angiology, Co-Chairman of the Scientific Council

  • Visiting Professor of Surgery Athens, Greece (1991)

    Visiting Professor of Surgery

  • Presentation- "Skeletal muscle for cardiac assistance" Athens, Greece (1991)

    Presentation- "Skeletal muscle for cardiac assistance"

  • Presentation- "Surgical treatment for ventricular arrhythmias" Athens, Greece (1991)

    Presentation- "Surgical treatment for ventricular arrhythmias"

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Contact Info

John Alex Elefteriades, MD
Patient Care Location
Yale Cardiac SurgeryYale Physicians Building
800 Howard Avenue, Ste 2nd Floor

New Haven, CT 06519
Mailing Address
Yale SurgeryPO Box 208039
New Haven, CT 06520-8062

Curriculum Vitae

Aortic Institute at Yale