ASA Triad (Samter's Triad)

What is ASA Triad (Samter’s Triad) ?

A percentage of asthma patients also have an adverse reaction to aspirin. In fact, ASA stands for acetylsalicylic acid, which is aspirin. However, patients can also react to NSAIDs (non-steroidal anti-inflammatory drugs) such as ibuprofen. A patient with ASA triad tends also to develop chronic rhinosinusitis, nasal polyps, and severe bronchial asthma. 

At the Yale Sinus and Allergy Program, we successfully treat patients with ASA Triad.

Symptoms of ASA Triad (Samter’s Triad)

The most common symptoms of ASA triad is rhinitis, or inflammation or irritation of the inner lining of the nose. Rhinitis is symptomized by sneezing, runny nose, or congestion. Asthma, nasal polyps, and aspirin sensitivity generally follow as the disorder progresses. 

A reaction to aspirin or NSAIDs (such as ibuprofen) can include severe asthma attacks and other reactions that may leave the patient unable to breathe. Alcohol may induce the same reaction.

This information should be used as a guideline. Not every symptom is included. If you have one or more of these symptoms, it does not mean that you have ASA Triad. Please contact your doctor if you think you may have this disorder.

Risk Factors of ASA Triad (Samter's Triad)

Having asthma, nasal problems, and nasal polyps may put you at a greater risk for developing ASA Triad. 

Anything that increases your chance of getting a disease is called a risk factor. Having a risk factor does not mean that you will get ASA Triad; not having risk factors does not mean that you will not get ASA Triad. If you think you may be at risk, you should talk to your doctor. 

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New Haven, CT 06510)

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